CA2584777A1 - Methods for heterologous expression of secondary metabolites - Google Patents

Methods for heterologous expression of secondary metabolites Download PDF

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Publication number
CA2584777A1
CA2584777A1 CA002584777A CA2584777A CA2584777A1 CA 2584777 A1 CA2584777 A1 CA 2584777A1 CA 002584777 A CA002584777 A CA 002584777A CA 2584777 A CA2584777 A CA 2584777A CA 2584777 A1 CA2584777 A1 CA 2584777A1
Authority
CA
Canada
Prior art keywords
host cell
genes
vector
biosynthetic pathway
gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002584777A
Other languages
English (en)
French (fr)
Inventor
Youming Zhang
Rolf Muller
Francis Stewart
Frank Gross
Silke C. Wenzel
Jun Fu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gene Bridges GmbH
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2584777A1 publication Critical patent/CA2584777A1/en
Abandoned legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/14Nitrogen or oxygen as hetero atom and at least one other diverse hetero ring atom in the same ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
CA002584777A 2004-10-26 2005-10-26 Methods for heterologous expression of secondary metabolites Abandoned CA2584777A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0423755.8A GB0423755D0 (en) 2004-10-26 2004-10-26 Methods for heterologus expression of secondary metabolites
GB0423755.8 2004-10-26
PCT/IB2005/003650 WO2006046152A2 (en) 2004-10-26 2005-10-26 Methods for heterologous expression of secondary metabolites

Publications (1)

Publication Number Publication Date
CA2584777A1 true CA2584777A1 (en) 2006-05-04

Family

ID=33485231

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002584777A Abandoned CA2584777A1 (en) 2004-10-26 2005-10-26 Methods for heterologous expression of secondary metabolites

Country Status (9)

Country Link
US (1) US20090298117A1 (enExample)
EP (1) EP1809749B1 (enExample)
JP (1) JP5566577B2 (enExample)
AT (1) ATE422547T1 (enExample)
AU (1) AU2005298341B2 (enExample)
CA (1) CA2584777A1 (enExample)
DE (1) DE602005012718D1 (enExample)
GB (1) GB0423755D0 (enExample)
WO (1) WO2006046152A2 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0605166A (pt) * 2006-11-03 2008-07-01 Inst Fleury método de determinação de ácido metilmalÈnico baseado na extração alquilativa associada à cromatografia lìquida acoplada à espectrometria de massas
GB0922108D0 (en) 2009-12-17 2010-02-03 Gene Bridges Gmbh Heterologous hosts
EP3027754B1 (en) 2013-08-02 2022-03-02 enEvolv, Inc. Processes and host cells for genome, pathway, and biomolecular engineering
WO2017151059A1 (en) * 2016-02-29 2017-09-08 Agency For Science, Technology And Research Multiplexable activation of silent biosynthetic clusters in native actinomycete hosts for natural product discovery
EP3938518A4 (en) 2019-03-12 2023-01-11 Terra Bioworks, Inc. EXPRESSION VECTOR

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1291420B1 (en) * 1997-12-05 2009-11-25 Europäisches Laboratorium Für Molekularbiologie (Embl) Novel DNA cloning method relying on the E.coli RECE/RECT recombination system
US6355412B1 (en) * 1999-07-09 2002-03-12 The European Molecular Biology Laboratory Methods and compositions for directed cloning and subcloning using homologous recombination
JP2004508810A (ja) * 2000-04-28 2004-03-25 コーサン バイオサイエンシーズ, インコーポレイテッド ポリケチドの生成
WO2003044186A2 (en) * 2001-11-22 2003-05-30 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Novel gene cluster of pederin biosynthesis genes
US20040005672A1 (en) * 2002-02-22 2004-01-08 Santi Daniel V. Heterologous production of polyketides

Also Published As

Publication number Publication date
WO2006046152A2 (en) 2006-05-04
AU2005298341A1 (en) 2006-05-04
JP5566577B2 (ja) 2014-08-06
EP1809749A2 (en) 2007-07-25
EP1809749B1 (en) 2009-02-11
US20090298117A1 (en) 2009-12-03
DE602005012718D1 (de) 2009-03-26
WO2006046152A3 (en) 2006-11-16
AU2005298341B2 (en) 2011-06-23
GB0423755D0 (en) 2004-11-24
JP2008517996A (ja) 2008-05-29
ATE422547T1 (de) 2009-02-15

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued

Effective date: 20131016