CA2582041C - Recombinant human t2 rnase and uses thereof - Google Patents
Recombinant human t2 rnase and uses thereof Download PDFInfo
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- CA2582041C CA2582041C CA2582041A CA2582041A CA2582041C CA 2582041 C CA2582041 C CA 2582041C CA 2582041 A CA2582041 A CA 2582041A CA 2582041 A CA2582041 A CA 2582041A CA 2582041 C CA2582041 C CA 2582041C
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- XLMPPFTZALNBFS-INIZCTEOSA-N vorozole Chemical compound C1([C@@H](C2=CC=C3N=NN(C3=C2)C)N2N=CN=C2)=CC=C(Cl)C=C1 XLMPPFTZALNBFS-INIZCTEOSA-N 0.000 description 1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P27/02—Ophthalmic agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
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- Public Health (AREA)
- Immunology (AREA)
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- Genetics & Genomics (AREA)
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- Cardiology (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Biotechnology (AREA)
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- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Ophthalmology & Optometry (AREA)
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- Urology & Nephrology (AREA)
- Surgery (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61370204P | 2004-09-29 | 2004-09-29 | |
| US60/613,702 | 2004-09-29 | ||
| PCT/IL2005/001041 WO2006035439A2 (en) | 2004-09-29 | 2005-09-28 | Recombinant human t2 rnase and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2582041A1 CA2582041A1 (en) | 2006-04-06 |
| CA2582041C true CA2582041C (en) | 2015-08-04 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2582041A Expired - Fee Related CA2582041C (en) | 2004-09-29 | 2005-09-28 | Recombinant human t2 rnase and uses thereof |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US8039240B2 (enExample) |
| EP (1) | EP1805319B1 (enExample) |
| JP (1) | JP5069562B2 (enExample) |
| AU (1) | AU2005288527B9 (enExample) |
| BR (1) | BRPI0516302A (enExample) |
| CA (1) | CA2582041C (enExample) |
| ES (1) | ES2524601T3 (enExample) |
| WO (1) | WO2006035439A2 (enExample) |
| ZA (1) | ZA200703313B (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4808346B2 (ja) * | 1999-08-30 | 2011-11-02 | イッサム・リサーチ・ディベロップメント・カンパニー・オブ・ザ・ヘブルー・ユニバーシティ・オブ・エルサレム | 哺乳類細胞の増殖を阻害する方法および組成物 |
| US7811981B2 (en) | 1999-08-30 | 2010-10-12 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Methods of and compositions for inhibiting the proliferation of mammalian cells |
| ATE548621T1 (de) * | 2006-08-01 | 2012-03-15 | Jscd Holding L P | Verbessertes trocknungssystem |
| AU2009309277A1 (en) * | 2008-10-30 | 2010-05-06 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Efficient expression of truncated human RNASET2 in E. Coli |
| WO2011084995A2 (en) * | 2010-01-05 | 2011-07-14 | Stratasys, Inc. | Support cleaning system |
| CN110237447B (zh) | 2013-09-27 | 2021-11-02 | 梅维昂医疗系统股份有限公司 | 粒子治疗系统 |
| US10675487B2 (en) | 2013-12-20 | 2020-06-09 | Mevion Medical Systems, Inc. | Energy degrader enabling high-speed energy switching |
| US9962560B2 (en) | 2013-12-20 | 2018-05-08 | Mevion Medical Systems, Inc. | Collimator and energy degrader |
| US20160340659A1 (en) | 2014-01-30 | 2016-11-24 | Yissum Research And Development Company Of The Hebrew University Of Jerusalem Ltd. | Actin binding peptides and compositions comprising same for inhibiting angiogenesis and treating medical conditions associated with same |
| US9661736B2 (en) | 2014-02-20 | 2017-05-23 | Mevion Medical Systems, Inc. | Scanning system for a particle therapy system |
| US10786689B2 (en) | 2015-11-10 | 2020-09-29 | Mevion Medical Systems, Inc. | Adaptive aperture |
| JP7082945B2 (ja) | 2016-03-17 | 2022-06-09 | シーダーズ―シナイ メディカル センター | Ｒｎａｓｅｔ２により炎症性腸疾患を診断する方法 |
| JP7059245B2 (ja) | 2016-07-08 | 2022-04-25 | メビオン・メディカル・システムズ・インコーポレーテッド | 治療計画の決定 |
| US11103730B2 (en) | 2017-02-23 | 2021-08-31 | Mevion Medical Systems, Inc. | Automated treatment in particle therapy |
| EP3645111B1 (en) | 2017-06-30 | 2025-04-23 | Mevion Medical Systems, Inc. | Configurable collimator controlled using linear motors |
| WO2020112890A1 (en) * | 2018-11-29 | 2020-06-04 | Cedars-Sinai Medical Center | Rnaset2 compositions and methods of treatment therewith |
| JP7311620B2 (ja) | 2019-03-08 | 2023-07-19 | メビオン・メディカル・システムズ・インコーポレーテッド | 粒子線治療システムのためのコリメータおよびエネルギーデグレーダ |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL154600B (nl) | 1971-02-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen. |
| NL154598B (nl) | 1970-11-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking. |
| NL154599B (nl) | 1970-12-28 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen, alsmede testverpakking. |
| US3901654A (en) | 1971-06-21 | 1975-08-26 | Biological Developments | Receptor assays of biologically active compounds employing biologically specific receptors |
| US3853987A (en) | 1971-09-01 | 1974-12-10 | W Dreyer | Immunological reagent and radioimmuno assay |
| US3867517A (en) | 1971-12-21 | 1975-02-18 | Abbott Lab | Direct radioimmunoassay for antigens and their antibodies |
| NL171930C (nl) | 1972-05-11 | 1983-06-01 | Akzo Nv | Werkwijze voor het aantonen en bepalen van haptenen, alsmede testverpakkingen. |
| US3850578A (en) | 1973-03-12 | 1974-11-26 | H Mcconnell | Process for assaying for biologically active molecules |
| US3935074A (en) | 1973-12-17 | 1976-01-27 | Syva Company | Antibody steric hindrance immunoassay with two antibodies |
| US3996345A (en) | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
| US4034074A (en) | 1974-09-19 | 1977-07-05 | The Board Of Trustees Of Leland Stanford Junior University | Universal reagent 2-site immunoradiometric assay using labelled anti (IgG) |
| US3984533A (en) | 1975-11-13 | 1976-10-05 | General Electric Company | Electrophoretic method of detecting antigen-antibody reaction |
| US4098876A (en) | 1976-10-26 | 1978-07-04 | Corning Glass Works | Reverse sandwich immunoassay |
| US4879219A (en) | 1980-09-19 | 1989-11-07 | General Hospital Corporation | Immunoassay utilizing monoclonal high affinity IgM antibodies |
| US5011771A (en) | 1984-04-12 | 1991-04-30 | The General Hospital Corporation | Multiepitopic immunometric assay |
| US5786457A (en) | 1989-02-23 | 1998-07-28 | Colorado State University Research Foundation | Hormone-nuclease compounds and method for regulating hormone related diseases |
| US5281521A (en) | 1992-07-20 | 1994-01-25 | The Trustees Of The University Of Pennsylvania | Modified avidin-biotin technique |
| WO1998039446A2 (en) * | 1997-03-07 | 1998-09-11 | Human Genome Sciences, Inc. | 70 human secreted proteins |
| AU2095299A (en) * | 1997-12-31 | 1999-07-19 | Incyte Pharmaceuticals, Inc. | Human signal peptide-containing proteins |
| JP4808346B2 (ja) | 1999-08-30 | 2011-11-02 | イッサム・リサーチ・ディベロップメント・カンパニー・オブ・ザ・ヘブルー・ユニバーシティ・オブ・エルサレム | 哺乳類細胞の増殖を阻害する方法および組成物 |
| US7811981B2 (en) | 1999-08-30 | 2010-10-12 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Methods of and compositions for inhibiting the proliferation of mammalian cells |
| US7101839B1 (en) | 1999-08-30 | 2006-09-05 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Methods of and compositions for inhibiting the proliferation of mammalian cells |
| KR100677108B1 (ko) | 2003-06-12 | 2007-02-01 | 삼성전자주식회사 | 정보 저장매체 |
-
2005
- 2005-09-28 BR BRPI0516302-1A patent/BRPI0516302A/pt not_active Application Discontinuation
- 2005-09-28 WO PCT/IL2005/001041 patent/WO2006035439A2/en not_active Ceased
- 2005-09-28 CA CA2582041A patent/CA2582041C/en not_active Expired - Fee Related
- 2005-09-28 AU AU2005288527A patent/AU2005288527B9/en not_active Ceased
- 2005-09-28 ES ES05789520.3T patent/ES2524601T3/es active Active
- 2005-09-28 JP JP2007534175A patent/JP5069562B2/ja not_active Expired - Fee Related
- 2005-09-28 EP EP05789520.3A patent/EP1805319B1/en not_active Not-in-force
- 2005-09-28 US US11/664,132 patent/US8039240B2/en not_active Expired - Fee Related
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2007
- 2007-04-23 ZA ZA200703313A patent/ZA200703313B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1805319A4 (en) | 2009-12-16 |
| JP5069562B2 (ja) | 2012-11-07 |
| CA2582041A1 (en) | 2006-04-06 |
| ES2524601T3 (es) | 2014-12-10 |
| WO2006035439A2 (en) | 2006-04-06 |
| EP1805319A2 (en) | 2007-07-11 |
| JP2008514224A (ja) | 2008-05-08 |
| ZA200703313B (en) | 2008-09-25 |
| US20080131419A1 (en) | 2008-06-05 |
| AU2005288527B9 (en) | 2011-07-28 |
| BRPI0516302A (pt) | 2008-09-02 |
| EP1805319B1 (en) | 2014-09-03 |
| AU2005288527B2 (en) | 2011-02-03 |
| AU2005288527A1 (en) | 2006-04-06 |
| HK1100329A1 (en) | 2007-09-14 |
| WO2006035439A3 (en) | 2007-06-28 |
| US8039240B2 (en) | 2011-10-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20200928 |