CA2571627C - Substituted aryl-amine derivatives and methods of use - Google Patents

Substituted aryl-amine derivatives and methods of use Download PDF

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Publication number
CA2571627C
CA2571627C CA2571627A CA2571627A CA2571627C CA 2571627 C CA2571627 C CA 2571627C CA 2571627 A CA2571627 A CA 2571627A CA 2571627 A CA2571627 A CA 2571627A CA 2571627 C CA2571627 C CA 2571627C
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Prior art keywords
compound
salt
phenyl
methyl
nitro
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Expired - Fee Related
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CA2571627A
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English (en)
French (fr)
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CA2571627A1 (en
Inventor
Chester Chenguang Yuan
Kevin Yang
Simon Van Der Plas
Babak Riahi
Michele Potashman
Vinod F. Patel
Rana Nomak
Aiwen Li
Qi Huang
Jean-Christophe Harmange
Benny C. Askew, Jr.
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Amgen Inc
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Amgen Inc
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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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  • General Chemical & Material Sciences (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • Diabetes (AREA)
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  • Ophthalmology & Optometry (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Cardiology (AREA)
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CA2571627A 2004-07-22 2005-07-20 Substituted aryl-amine derivatives and methods of use Expired - Fee Related CA2571627C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US59054404P 2004-07-22 2004-07-22
US60/590,544 2004-07-22
US11/185,556 2005-07-19
US11/185,556 US7507748B2 (en) 2004-07-22 2005-07-19 Substituted aryl-amine derivatives and methods of use
PCT/US2005/025800 WO2006012374A1 (en) 2004-07-22 2005-07-20 Substituted aryl-amine derivatives and methods of use

Publications (2)

Publication Number Publication Date
CA2571627A1 CA2571627A1 (en) 2006-02-02
CA2571627C true CA2571627C (en) 2010-02-16

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CA2571627A Expired - Fee Related CA2571627C (en) 2004-07-22 2005-07-20 Substituted aryl-amine derivatives and methods of use

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US (2) US7507748B2 (https=)
EP (1) EP1773817B1 (https=)
JP (1) JP2008507539A (https=)
AT (1) ATE440834T1 (https=)
AU (1) AU2005267161B2 (https=)
CA (1) CA2571627C (https=)
DE (1) DE602005016261D1 (https=)
ES (1) ES2331318T3 (https=)
MX (1) MX2007000672A (https=)
WO (1) WO2006012374A1 (https=)

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US7507748B2 (en) * 2004-07-22 2009-03-24 Amgen Inc. Substituted aryl-amine derivatives and methods of use
US20070212298A1 (en) * 2004-08-25 2007-09-13 Prefix Suffix Use of the combination comprising temozolomide and tnf-alpha for treating glioblastoma
US8586571B2 (en) 2007-10-18 2013-11-19 Takeda Pharmaceutical Company Limited Heterocyclic compound
WO2011161217A2 (en) 2010-06-23 2011-12-29 Palacký University in Olomouc Targeting of vegfr2
EP2630122B1 (en) * 2010-10-18 2016-11-30 RaQualia Pharma Inc Arylamide derivatives as ttx-s blockers
EP2675802A1 (en) * 2011-02-14 2013-12-25 Council of Scientific & Industrial Research 2-anilino nicotinyl linked 2-amino benzothiazole conjugates and process for the preparation thereof
WO2012162291A1 (en) * 2011-05-24 2012-11-29 The Wistar Institute Compositions and methods for modulating the activity of epstein-barr nuclear antigen 1
KR101412794B1 (ko) 2011-07-27 2014-07-01 보령제약 주식회사 혈관생성억제 작용을 갖는 신규한 화합물, 이의 제조방법 및 이를 포함하는 약학적 조성물
UA112897C2 (uk) 2012-05-09 2016-11-10 Байєр Фарма Акцієнгезелльшафт Біциклічно заміщені урацили та їх застосування для лікування і/або профілактики захворювань
WO2014058729A1 (en) * 2012-10-09 2014-04-17 California Institute Of Technology In vivo and in vitro carbene insertion and nitrene transfer reactions catalyzed by heme enzymes
EP2906518A4 (en) 2012-10-09 2016-07-27 California Inst Of Techn CYCLES CATALYZED IN VIVO AND IN VITRO OLEFINCYCLOPROPANATION
KR101652577B1 (ko) * 2013-04-19 2016-08-30 영남대학교 산학협력단 아미도피리딘올 유도체 또는 이의 약제학적 허용가능한 염 및 이를 유효성분으로 함유하는 혈관신생으로 인한 질환의 예방 또는 치료용 약학조성물
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