CA2558426C - Formulations decreasing particle exhalation - Google Patents
Formulations decreasing particle exhalation Download PDFInfo
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- CA2558426C CA2558426C CA2558426A CA2558426A CA2558426C CA 2558426 C CA2558426 C CA 2558426C CA 2558426 A CA2558426 A CA 2558426A CA 2558426 A CA2558426 A CA 2558426A CA 2558426 C CA2558426 C CA 2558426C
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- pulmonary infection
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Classifications
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Pulmonology (AREA)
- Inorganic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Otolaryngology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (13)
| Application Number | Priority Date | Filing Date | Title |
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| US56047004P | 2004-04-07 | 2004-04-07 | |
| US60/560,470 | 2004-04-07 | ||
| US56418904P | 2004-04-21 | 2004-04-21 | |
| US60/564,189 | 2004-04-21 | ||
| US57263104P | 2004-05-19 | 2004-05-19 | |
| US60/572,631 | 2004-05-19 | ||
| US57942504P | 2004-06-14 | 2004-06-14 | |
| US60/579,425 | 2004-06-14 | ||
| US10/990,996 US20050207983A1 (en) | 2004-03-05 | 2004-11-17 | Formulations decreasing particle exhalation |
| US10/990,996 | 2004-11-17 | ||
| PCT/US2005/006903 WO2005084638A2 (en) | 2004-03-05 | 2005-03-03 | Formulations decreasing infectivity of pulmonary diseases |
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| CA2558426A1 CA2558426A1 (en) | 2005-09-15 |
| CA2558426C true CA2558426C (en) | 2011-05-03 |
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| Country | Link |
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| US (4) | US20050207983A1 (enExample) |
| EP (1) | EP1732606A2 (enExample) |
| JP (1) | JP2007527430A (enExample) |
| AU (2) | AU2005219431B2 (enExample) |
| CA (1) | CA2558426C (enExample) |
| WO (1) | WO2005084638A2 (enExample) |
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| CA2483917C (en) * | 2002-05-02 | 2013-07-30 | President And Fellows Of Harvard College | Formulations limiting spread of pulmonary infections |
| US20050207983A1 (en) * | 2004-03-05 | 2005-09-22 | Pulmatrix, Inc. | Formulations decreasing particle exhalation |
| JP2008540680A (ja) | 2005-05-18 | 2008-11-20 | プルマトリックス インコーポレイテッド | 粘膜内壁の生物物理学的な性質を変化させる製剤 |
| EP1834651A1 (en) * | 2006-03-15 | 2007-09-19 | Universiteit Gent | Compositions and methods for veterinary vaccination |
| WO2008055208A1 (en) * | 2006-11-01 | 2008-05-08 | New Jersey Institute Of Technology | Aerogel-based filtration of gas phase systems |
| US20080260863A1 (en) * | 2007-04-20 | 2008-10-23 | Pre Holding, Inc. | Compositions for mucociliary clearance and methods for administering same |
| JP5258892B2 (ja) * | 2007-10-02 | 2013-08-07 | オリン，アナ−キャリン | 呼気粒子の捕集及び測定 |
| ATE538774T1 (de) * | 2009-03-26 | 2012-01-15 | Pulmatrix Inc | Pharmazeutische formulierungen und verfahren zur behandlung von atemwegsinfektionen |
| CA2754684A1 (en) * | 2009-03-26 | 2010-09-30 | Pulmatrix, Inc. | Calcium citrate and calcium lactate formulations for alteration of biophysical properties of mucosal lining |
| EP2410981B2 (en) | 2009-03-26 | 2020-02-26 | Pulmatrix Operating Company, Inc. | Dry powder formulations and methods for treating pulmonary diseases |
| WO2010111640A2 (en) * | 2009-03-26 | 2010-09-30 | Pulmatrix, Inc. | Anti-influenza formulations and methods |
| WO2012012498A2 (en) * | 2010-07-20 | 2012-01-26 | Pulmatrix, Inc. | Use of trp channel agonists to treat infections |
| US9061352B2 (en) | 2010-08-30 | 2015-06-23 | Pulmatrix, Inc. | Dry powder formulations and methods for treating pulmonary diseases |
| WO2012030647A1 (en) | 2010-08-30 | 2012-03-08 | Pulmatrix, Inc. | Treatment of cystic fibrosis using calcium lactate, leucine and sodium chloride in a respiraple dry powder |
| CA2812417C (en) | 2010-09-29 | 2019-10-22 | Pulmatrix, Inc. | Cationic dry powders |
| CN107096014B (zh) | 2010-09-29 | 2022-07-15 | 普马特里克斯营业公司 | 吸入用单价金属阳离子干粉剂 |
| KR101211672B1 (ko) | 2010-12-10 | 2012-12-12 | 한국철도기술연구원 | 재채기 모사장치 및 모사방법 |
| CN104487075A (zh) | 2012-02-29 | 2015-04-01 | 普马特里克斯公司 | 可吸入干粉剂 |
| WO2014165303A1 (en) | 2013-04-01 | 2014-10-09 | Pulmatrix, Inc. | Tiotropium dry powders |
| CN107106641B (zh) | 2014-10-31 | 2021-12-21 | 葛兰素史密斯克莱知识产权发展有限公司 | 粉末制剂 |
| MA41124A (fr) * | 2014-12-05 | 2017-10-10 | Sun Pharmaceutical Ind Ltd | Compositions en suspension à libération prolongée à rétention gastrique |
| US12337064B2 (en) | 2018-09-05 | 2025-06-24 | Sensory Cloud, Inc. | Formulations and compositions for ortho- and/or retro-nasal delivery and associated systems, methods and articles |
| US20220000767A1 (en) * | 2020-07-06 | 2022-01-06 | Sensory Cloud, Inc. | Nasal hygiene compositions, antimicrobial treatments, devices, and articles for delivery of same to the nose, trachea and main bronchi |
| US20220051592A1 (en) * | 2020-08-17 | 2022-02-17 | Massachusetts Institute Of Technology | Respiratory system simulator systems and methods |
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| DE3229179C2 (de) | 1982-08-05 | 1986-04-17 | A. Nattermann & Cie GmbH, 5000 Köln | Lungensurfactant |
| US4826844A (en) * | 1987-09-30 | 1989-05-02 | American Home Products Corporation | Substituted 1-(aralkyl-piperazinoalkyl) cycloalkanols |
| US4899914A (en) * | 1988-11-04 | 1990-02-13 | Ciba-Geigy Corporation | Method for producing a sterile preservative-free aerosol saline solution |
| US5230884A (en) * | 1990-09-11 | 1993-07-27 | University Of Wales College Of Cardiff | Aerosol formulations including proteins and peptides solubilized in reverse micelles and process for making the aerosol formulations |
| US5175152A (en) * | 1990-09-28 | 1992-12-29 | Singh Nikhilesh N | Composition containing ephedrine base and alkyl salicylate for the delivery of ephedrine base in vapor form |
| US5211944A (en) | 1990-10-12 | 1993-05-18 | Shaman Pharmaceuticals, Inc. | Proanthocyanidin polymers having antiviral activity and methods of obtaining same |
| US5466680A (en) | 1992-03-26 | 1995-11-14 | Cytologics, Inc. | Method and compositions for enhancing white blood cell functioning on a mucosal or cutaneous surface |
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| AUPM411494A0 (en) * | 1994-02-25 | 1994-03-24 | Central Sydney Area Health Service | Method and device for the provocation of upper or lower airway narrowing and/or the induction of sputum |
| US5633003A (en) | 1994-03-31 | 1997-05-27 | Cantor; Jerome O. | Use of intratracheally administered hyaluronic acid to ameliorate emphysema |
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| US5863563A (en) | 1994-10-20 | 1999-01-26 | Alphagene Inc. | Treatment of pulmonary conditions associated with insufficient secretion of surfactant |
| US5654007A (en) * | 1995-06-07 | 1997-08-05 | Inhale Therapeutic Systems | Methods and system for processing dispersible fine powders |
| US5628984A (en) * | 1995-07-31 | 1997-05-13 | University Of North Carolina At Chapel Hill | Method of detecting lung disease |
| GB9606677D0 (en) | 1996-03-29 | 1996-06-05 | Glaxo Wellcome Inc | Process and device |
| US6083922A (en) * | 1996-04-02 | 2000-07-04 | Pathogenesis, Corp. | Method and a tobramycin aerosol formulation for treatment prevention and containment of tuberculosis |
| USRE37053E1 (en) * | 1996-05-24 | 2001-02-13 | Massachusetts Institute Of Technology | Particles incorporating surfactants for pulmonary drug delivery |
| US5855913A (en) | 1997-01-16 | 1999-01-05 | Massachusetts Instite Of Technology | Particles incorporating surfactants for pulmonary drug delivery |
| US5985309A (en) | 1996-05-24 | 1999-11-16 | Massachusetts Institute Of Technology | Preparation of particles for inhalation |
| US5874064A (en) | 1996-05-24 | 1999-02-23 | Massachusetts Institute Of Technology | Aerodynamically light particles for pulmonary drug delivery |
| DE19653969A1 (de) * | 1996-12-20 | 1998-06-25 | Boehringer Ingelheim Kg | Neue wässrige Arzneimittelzubereitung zur Erzeugung treibgasfreier Aerosole |
| US5883084A (en) | 1998-06-08 | 1999-03-16 | Clarion Pharmaceuticals Inc. | Treatment of respiratory diseases utilizing α-tocopheryl-phosphocholine |
| SE9802073D0 (sv) | 1998-06-11 | 1998-06-11 | Astra Ab | New use |
| FR2780285B1 (fr) | 1998-06-29 | 2001-10-05 | Goemar Lab Sa | Utilisation de solutions salines isoosmotiques, leur procede de preparation et medicaments anti-inflammatoires a base de ces solutions |
| US6926911B1 (en) | 1998-12-22 | 2005-08-09 | The University Of North Carolina At Chapel Hill | Compounds and methods for the treatment of airway diseases and for the delivery of airway drugs |
| US6083933A (en) * | 1999-04-19 | 2000-07-04 | Stellar International Inc. | Treatment of cystitis-like symptoms with chondroitin sulfate following administration of a challenge solution |
| WO2002009574A2 (en) * | 2000-08-01 | 2002-02-07 | Shofner Engineering Associates, Inc. | Generation, delivery, measurement and control of aerosol boli for diagnostics and treatment of the respiratory tract |
| AU2002245181B2 (en) * | 2000-12-21 | 2006-06-29 | Nektar Therapeutics | Pulmonary delivery of polyene antifungal agents |
| US6660249B2 (en) * | 2000-12-27 | 2003-12-09 | Salus Pharma, Inc. | Inhalable dry powder aztreonam for treatment and prevention of pulmonary bacterial infections |
| US20030138403A1 (en) * | 2001-06-29 | 2003-07-24 | Maxygen Aps | Interferon formulations |
| CA2483917C (en) * | 2002-05-02 | 2013-07-30 | President And Fellows Of Harvard College | Formulations limiting spread of pulmonary infections |
| EP1503744A1 (en) * | 2002-05-13 | 2005-02-09 | Alexza Molecular Delivery Corporation | Delivery of drug amines through an inhalation route |
| US20050207983A1 (en) * | 2004-03-05 | 2005-09-22 | Pulmatrix, Inc. | Formulations decreasing particle exhalation |
| US20070275091A1 (en) | 2004-03-30 | 2007-11-29 | Malcolm King | Compositions And Methods For Improved Mucus Function |
| US8627821B2 (en) | 2005-01-10 | 2014-01-14 | Pulmatrix, Inc. | Method and device for decreasing contamination |
| WO2006102438A2 (en) | 2005-03-23 | 2006-09-28 | Ihc Intellectual Asset Management, Llc | Methods and compositions for irrigation of mucosal tissues |
| JP2008540680A (ja) | 2005-05-18 | 2008-11-20 | プルマトリックス インコーポレイテッド | 粘膜内壁の生物物理学的な性質を変化させる製剤 |
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2004
- 2004-11-17 US US10/990,996 patent/US20050207983A1/en not_active Abandoned
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2005
- 2005-03-03 EP EP05757878A patent/EP1732606A2/en not_active Withdrawn
- 2005-03-03 JP JP2007501976A patent/JP2007527430A/ja active Pending
- 2005-03-03 CA CA2558426A patent/CA2558426C/en not_active Expired - Lifetime
- 2005-03-03 AU AU2005219431A patent/AU2005219431B2/en not_active Expired
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2012
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Also Published As
| Publication number | Publication date |
|---|---|
| JP2007527430A (ja) | 2007-09-27 |
| CA2558426A1 (en) | 2005-09-15 |
| AU2005219431B2 (en) | 2009-07-16 |
| US8591866B2 (en) | 2013-11-26 |
| EP1732606A2 (en) | 2006-12-20 |
| AU2009225363A1 (en) | 2009-11-05 |
| US20130078282A1 (en) | 2013-03-28 |
| AU2005219431A8 (en) | 2009-07-02 |
| US20070270502A1 (en) | 2007-11-22 |
| WO2005084638A2 (en) | 2005-09-15 |
| AU2009225363B2 (en) | 2012-02-23 |
| US20050207983A1 (en) | 2005-09-22 |
| AU2005219431A1 (en) | 2005-09-15 |
| US8187637B2 (en) | 2012-05-29 |
| WO2005084638A3 (en) | 2006-06-15 |
| US20150079173A1 (en) | 2015-03-19 |
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