AU2005219431B2 - Formulations decreasing infectivity of pulmonary diseases - Google Patents

Formulations decreasing infectivity of pulmonary diseases Download PDF

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Publication number
AU2005219431B2
AU2005219431B2 AU2005219431A AU2005219431A AU2005219431B2 AU 2005219431 B2 AU2005219431 B2 AU 2005219431B2 AU 2005219431 A AU2005219431 A AU 2005219431A AU 2005219431 A AU2005219431 A AU 2005219431A AU 2005219431 B2 AU2005219431 B2 AU 2005219431B2
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AU
Australia
Prior art keywords
formulation
endogenous
fluid
particles
individual
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU2005219431A
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English (en)
Other versions
AU2005219431A8 (en
AU2005219431A1 (en
Inventor
Robert W. Clarke
David A. Edwards
Jeffrey P. Katstra
Jonathan C. Man
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pulmatrix Inc
Original Assignee
Pulmatrix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pulmatrix Inc filed Critical Pulmatrix Inc
Publication of AU2005219431A1 publication Critical patent/AU2005219431A1/en
Publication of AU2005219431A8 publication Critical patent/AU2005219431A8/en
Application granted granted Critical
Publication of AU2005219431B2 publication Critical patent/AU2005219431B2/en
Priority to AU2009225363A priority Critical patent/AU2009225363B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Pulmonology (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU2005219431A 2004-03-05 2005-03-03 Formulations decreasing infectivity of pulmonary diseases Expired AU2005219431B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2009225363A AU2009225363B2 (en) 2004-03-05 2009-10-14 Formulations for decreasing infectivity of pulmonary disease

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US55060104P 2004-03-05 2004-03-05
US60/550,601 2004-03-05
US56047004P 2004-04-07 2004-04-07
US60/560,470 2004-04-07
US56418904P 2004-04-21 2004-04-21
US60/564,189 2004-04-21
US57263104P 2004-05-19 2004-05-19
US60/572,631 2004-05-19
US57942504P 2004-06-14 2004-06-14
US60/579,425 2004-06-14
US10/990,996 US20050207983A1 (en) 2004-03-05 2004-11-17 Formulations decreasing particle exhalation
US10/990,996 2004-11-17
PCT/US2005/006903 WO2005084638A2 (en) 2004-03-05 2005-03-03 Formulations decreasing infectivity of pulmonary diseases

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2009225363A Division AU2009225363B2 (en) 2004-03-05 2009-10-14 Formulations for decreasing infectivity of pulmonary disease

Publications (3)

Publication Number Publication Date
AU2005219431A1 AU2005219431A1 (en) 2005-09-15
AU2005219431A8 AU2005219431A8 (en) 2009-07-02
AU2005219431B2 true AU2005219431B2 (en) 2009-07-16

Family

ID=34923561

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2005219431A Expired AU2005219431B2 (en) 2004-03-05 2005-03-03 Formulations decreasing infectivity of pulmonary diseases
AU2009225363A Expired AU2009225363B2 (en) 2004-03-05 2009-10-14 Formulations for decreasing infectivity of pulmonary disease

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2009225363A Expired AU2009225363B2 (en) 2004-03-05 2009-10-14 Formulations for decreasing infectivity of pulmonary disease

Country Status (6)

Country Link
US (4) US20050207983A1 (enExample)
EP (1) EP1732606A2 (enExample)
JP (1) JP2007527430A (enExample)
AU (2) AU2005219431B2 (enExample)
CA (1) CA2558426C (enExample)
WO (1) WO2005084638A2 (enExample)

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CA2483917C (en) * 2002-05-02 2013-07-30 President And Fellows Of Harvard College Formulations limiting spread of pulmonary infections
US20050207983A1 (en) * 2004-03-05 2005-09-22 Pulmatrix, Inc. Formulations decreasing particle exhalation
JP2008540680A (ja) 2005-05-18 2008-11-20 プルマトリックス インコーポレイテッド 粘膜内壁の生物物理学的な性質を変化させる製剤
EP1834651A1 (en) * 2006-03-15 2007-09-19 Universiteit Gent Compositions and methods for veterinary vaccination
WO2008055208A1 (en) * 2006-11-01 2008-05-08 New Jersey Institute Of Technology Aerogel-based filtration of gas phase systems
US20080260863A1 (en) * 2007-04-20 2008-10-23 Pre Holding, Inc. Compositions for mucociliary clearance and methods for administering same
JP5258892B2 (ja) * 2007-10-02 2013-08-07 オリン,アナ−キャリン 呼気粒子の捕集及び測定
ATE538774T1 (de) * 2009-03-26 2012-01-15 Pulmatrix Inc Pharmazeutische formulierungen und verfahren zur behandlung von atemwegsinfektionen
CA2754684A1 (en) * 2009-03-26 2010-09-30 Pulmatrix, Inc. Calcium citrate and calcium lactate formulations for alteration of biophysical properties of mucosal lining
EP2410981B2 (en) 2009-03-26 2020-02-26 Pulmatrix Operating Company, Inc. Dry powder formulations and methods for treating pulmonary diseases
WO2010111640A2 (en) * 2009-03-26 2010-09-30 Pulmatrix, Inc. Anti-influenza formulations and methods
WO2012012498A2 (en) * 2010-07-20 2012-01-26 Pulmatrix, Inc. Use of trp channel agonists to treat infections
US9061352B2 (en) 2010-08-30 2015-06-23 Pulmatrix, Inc. Dry powder formulations and methods for treating pulmonary diseases
WO2012030647A1 (en) 2010-08-30 2012-03-08 Pulmatrix, Inc. Treatment of cystic fibrosis using calcium lactate, leucine and sodium chloride in a respiraple dry powder
CA2812417C (en) 2010-09-29 2019-10-22 Pulmatrix, Inc. Cationic dry powders
CN107096014B (zh) 2010-09-29 2022-07-15 普马特里克斯营业公司 吸入用单价金属阳离子干粉剂
KR101211672B1 (ko) 2010-12-10 2012-12-12 한국철도기술연구원 재채기 모사장치 및 모사방법
CN104487075A (zh) 2012-02-29 2015-04-01 普马特里克斯公司 可吸入干粉剂
WO2014165303A1 (en) 2013-04-01 2014-10-09 Pulmatrix, Inc. Tiotropium dry powders
CN107106641B (zh) 2014-10-31 2021-12-21 葛兰素史密斯克莱知识产权发展有限公司 粉末制剂
MA41124A (fr) * 2014-12-05 2017-10-10 Sun Pharmaceutical Ind Ltd Compositions en suspension à libération prolongée à rétention gastrique
US12337064B2 (en) 2018-09-05 2025-06-24 Sensory Cloud, Inc. Formulations and compositions for ortho- and/or retro-nasal delivery and associated systems, methods and articles
US20220000767A1 (en) * 2020-07-06 2022-01-06 Sensory Cloud, Inc. Nasal hygiene compositions, antimicrobial treatments, devices, and articles for delivery of same to the nose, trachea and main bronchi
US20220051592A1 (en) * 2020-08-17 2022-02-17 Massachusetts Institute Of Technology Respiratory system simulator systems and methods

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0367723A2 (en) * 1988-11-04 1990-05-09 Ciba-Geigy Ag Method for producing a sterile preservative-free aerosol solution
US5175152A (en) * 1990-09-28 1992-12-29 Singh Nikhilesh N Composition containing ephedrine base and alkyl salicylate for the delivery of ephedrine base in vapor form
US6083922A (en) * 1996-04-02 2000-07-04 Pathogenesis, Corp. Method and a tobramycin aerosol formulation for treatment prevention and containment of tuberculosis
WO2002009574A2 (en) * 2000-08-01 2002-02-07 Shofner Engineering Associates, Inc. Generation, delivery, measurement and control of aerosol boli for diagnostics and treatment of the respiratory tract
WO2003092654A1 (en) * 2002-05-02 2003-11-13 President And Fellows Of Harvard College Formulations limiting spread of pulmonary infections

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DE3229179C2 (de) 1982-08-05 1986-04-17 A. Nattermann & Cie GmbH, 5000 Köln Lungensurfactant
US4826844A (en) * 1987-09-30 1989-05-02 American Home Products Corporation Substituted 1-(aralkyl-piperazinoalkyl) cycloalkanols
US5230884A (en) * 1990-09-11 1993-07-27 University Of Wales College Of Cardiff Aerosol formulations including proteins and peptides solubilized in reverse micelles and process for making the aerosol formulations
US5211944A (en) 1990-10-12 1993-05-18 Shaman Pharmaceuticals, Inc. Proanthocyanidin polymers having antiviral activity and methods of obtaining same
US5466680A (en) 1992-03-26 1995-11-14 Cytologics, Inc. Method and compositions for enhancing white blood cell functioning on a mucosal or cutaneous surface
JP3961029B2 (ja) 1992-06-24 2007-08-15 博 木戸 インフルエンザウィルス感染防止剤
US5709202A (en) * 1993-05-21 1998-01-20 Aradigm Corporation Intrapulmonary delivery of aerosolized formulations
AUPM411494A0 (en) * 1994-02-25 1994-03-24 Central Sydney Area Health Service Method and device for the provocation of upper or lower airway narrowing and/or the induction of sputum
US5633003A (en) 1994-03-31 1997-05-27 Cantor; Jerome O. Use of intratracheally administered hyaluronic acid to ameliorate emphysema
US5633033A (en) * 1994-04-18 1997-05-27 Matsushita Electric Industrial Co., Ltd. Method for manufacturing chalcopyrite film
US5863563A (en) 1994-10-20 1999-01-26 Alphagene Inc. Treatment of pulmonary conditions associated with insufficient secretion of surfactant
US5654007A (en) * 1995-06-07 1997-08-05 Inhale Therapeutic Systems Methods and system for processing dispersible fine powders
US5628984A (en) * 1995-07-31 1997-05-13 University Of North Carolina At Chapel Hill Method of detecting lung disease
GB9606677D0 (en) 1996-03-29 1996-06-05 Glaxo Wellcome Inc Process and device
USRE37053E1 (en) * 1996-05-24 2001-02-13 Massachusetts Institute Of Technology Particles incorporating surfactants for pulmonary drug delivery
US5855913A (en) 1997-01-16 1999-01-05 Massachusetts Instite Of Technology Particles incorporating surfactants for pulmonary drug delivery
US5985309A (en) 1996-05-24 1999-11-16 Massachusetts Institute Of Technology Preparation of particles for inhalation
US5874064A (en) 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
DE19653969A1 (de) * 1996-12-20 1998-06-25 Boehringer Ingelheim Kg Neue wässrige Arzneimittelzubereitung zur Erzeugung treibgasfreier Aerosole
US5883084A (en) 1998-06-08 1999-03-16 Clarion Pharmaceuticals Inc. Treatment of respiratory diseases utilizing α-tocopheryl-phosphocholine
SE9802073D0 (sv) 1998-06-11 1998-06-11 Astra Ab New use
FR2780285B1 (fr) 1998-06-29 2001-10-05 Goemar Lab Sa Utilisation de solutions salines isoosmotiques, leur procede de preparation et medicaments anti-inflammatoires a base de ces solutions
US6926911B1 (en) 1998-12-22 2005-08-09 The University Of North Carolina At Chapel Hill Compounds and methods for the treatment of airway diseases and for the delivery of airway drugs
US6083933A (en) * 1999-04-19 2000-07-04 Stellar International Inc. Treatment of cystitis-like symptoms with chondroitin sulfate following administration of a challenge solution
AU2002245181B2 (en) * 2000-12-21 2006-06-29 Nektar Therapeutics Pulmonary delivery of polyene antifungal agents
US6660249B2 (en) * 2000-12-27 2003-12-09 Salus Pharma, Inc. Inhalable dry powder aztreonam for treatment and prevention of pulmonary bacterial infections
US20030138403A1 (en) * 2001-06-29 2003-07-24 Maxygen Aps Interferon formulations
EP1503744A1 (en) * 2002-05-13 2005-02-09 Alexza Molecular Delivery Corporation Delivery of drug amines through an inhalation route
US20050207983A1 (en) * 2004-03-05 2005-09-22 Pulmatrix, Inc. Formulations decreasing particle exhalation
US20070275091A1 (en) 2004-03-30 2007-11-29 Malcolm King Compositions And Methods For Improved Mucus Function
US8627821B2 (en) 2005-01-10 2014-01-14 Pulmatrix, Inc. Method and device for decreasing contamination
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Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0367723A2 (en) * 1988-11-04 1990-05-09 Ciba-Geigy Ag Method for producing a sterile preservative-free aerosol solution
US5175152A (en) * 1990-09-28 1992-12-29 Singh Nikhilesh N Composition containing ephedrine base and alkyl salicylate for the delivery of ephedrine base in vapor form
US6083922A (en) * 1996-04-02 2000-07-04 Pathogenesis, Corp. Method and a tobramycin aerosol formulation for treatment prevention and containment of tuberculosis
WO2002009574A2 (en) * 2000-08-01 2002-02-07 Shofner Engineering Associates, Inc. Generation, delivery, measurement and control of aerosol boli for diagnostics and treatment of the respiratory tract
WO2003092654A1 (en) * 2002-05-02 2003-11-13 President And Fellows Of Harvard College Formulations limiting spread of pulmonary infections

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Title
Cataldo Didieer et al, Chest, Vol.120, no. 6, Dec 2001, pp 1815-1821, *
Hardy Kyle G et al, Chest, vol 114, no. 2, Aug 1998, pp 404-410 *

Also Published As

Publication number Publication date
JP2007527430A (ja) 2007-09-27
CA2558426A1 (en) 2005-09-15
US8591866B2 (en) 2013-11-26
EP1732606A2 (en) 2006-12-20
AU2009225363A1 (en) 2009-11-05
US20130078282A1 (en) 2013-03-28
AU2005219431A8 (en) 2009-07-02
US20070270502A1 (en) 2007-11-22
WO2005084638A2 (en) 2005-09-15
AU2009225363B2 (en) 2012-02-23
CA2558426C (en) 2011-05-03
US20050207983A1 (en) 2005-09-22
AU2005219431A1 (en) 2005-09-15
US8187637B2 (en) 2012-05-29
WO2005084638A3 (en) 2006-06-15
US20150079173A1 (en) 2015-03-19

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Legal Events

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TH Corrigenda

Free format text: IN VOL 20, NO 41, PAGE(S) 4042 UNDER THE HEADING PCT APPLICATIONS THAT HAVE ENTERED THE NATIONAL PHASE -NAME INDEX UNDER THE NAME PULMATRIX, INC., APPLICATION NO. 2005219431, UNDER INID (71) CORRECT THE NAME TO READ PULMATRIX INC.

FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired