CA2542277A1 - Method for the treatment or prevention of respiratory inflammation with a cyclooxygenase-2 inhibitor in combination with a phosphodiesterase 4 inhibitor and compositions therewith - Google Patents
Method for the treatment or prevention of respiratory inflammation with a cyclooxygenase-2 inhibitor in combination with a phosphodiesterase 4 inhibitor and compositions therewith Download PDFInfo
- Publication number
- CA2542277A1 CA2542277A1 CA002542277A CA2542277A CA2542277A1 CA 2542277 A1 CA2542277 A1 CA 2542277A1 CA 002542277 A CA002542277 A CA 002542277A CA 2542277 A CA2542277 A CA 2542277A CA 2542277 A1 CA2542277 A1 CA 2542277A1
- Authority
- CA
- Canada
- Prior art keywords
- trifluoromethyl
- carboxylic acid
- benzopyran
- alkyl
- chloro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US51309903P | 2003-10-21 | 2003-10-21 | |
US60/513,099 | 2003-10-21 | ||
PCT/US2004/034685 WO2005041864A2 (en) | 2003-10-21 | 2004-10-21 | Combination of cyclooxygenase-2 inhibitor and phosphodiesterase 4 inhibitor and method |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2542277A1 true CA2542277A1 (en) | 2005-05-12 |
Family
ID=34549248
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002542277A Abandoned CA2542277A1 (en) | 2003-10-21 | 2004-10-21 | Method for the treatment or prevention of respiratory inflammation with a cyclooxygenase-2 inhibitor in combination with a phosphodiesterase 4 inhibitor and compositions therewith |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1691797A2 (es) |
JP (1) | JP2007509154A (es) |
BR (1) | BRPI0415753A (es) |
CA (1) | CA2542277A1 (es) |
MX (1) | MXPA06004499A (es) |
WO (1) | WO2005041864A2 (es) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8541456B2 (en) | 2005-03-08 | 2013-09-24 | Takeda Gmbh | Roflumilast for the treatment of diabetes mellitus type 2 |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MY140561A (en) | 2002-02-20 | 2009-12-31 | Nycomed Gmbh | Dosage form containing pde 4 inhibitor as active ingredient |
GB0218868D0 (en) | 2002-08-14 | 2002-09-25 | Nasir Muhammed A | Improved airway management device |
ATE447555T1 (de) | 2003-03-10 | 2009-11-15 | Nycomed Gmbh | Neues verfahren zur herstellung vonroflumilast |
EP1755595A1 (en) * | 2004-05-10 | 2007-02-28 | Altana Pharma AG | Use of roflumilast for the prophylaxis or treatment of emphysema |
EP2258350B1 (en) | 2005-03-16 | 2014-12-24 | Takeda GmbH | Taste masked dosage form containing roflumilast |
EP2547335A4 (en) * | 2010-03-15 | 2014-04-16 | Univ Virginia Commonwealth | AEROSOLIC DAPSONE AS THERAPY AGAINST INFLAMMATION OF THE RESPIRATORY SYSTEM AND ANOMALY OF MUCOCILIARY TRANSPORT |
GB201010647D0 (en) | 2010-06-24 | 2010-08-11 | Docsinnovent Ltd | Stopper device |
GB201201438D0 (en) | 2012-01-27 | 2012-03-14 | Docsinnovent Ltd | Improved stopper device |
USD761952S1 (en) | 2012-07-27 | 2016-07-19 | Docsinnovent Limited | Airway device |
WO2013131255A1 (en) * | 2012-03-07 | 2013-09-12 | Scinopharm (Changshu) Pharmaceutical, Ltd. | Preparation method of roflumilast |
EP2846793A1 (en) * | 2012-05-09 | 2015-03-18 | Institut National de la Santé et de la Recherche Médicale (INSERM) | Methods and pharmaceutical compositions for prevention or treatment of chronic obstructive pulmonary disease |
WO2014026959A1 (en) * | 2012-08-13 | 2014-02-20 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and pharmaceutical compositions for treatment of cystic fibrosis |
GB2521375C (en) | 2013-12-17 | 2021-09-29 | Aslam Nasir Muhammed | Intubating Airway Device |
USD842456S1 (en) | 2015-12-15 | 2019-03-05 | Intersurgical Ag | Airway device |
GB201720733D0 (en) | 2017-12-13 | 2018-01-24 | Ashkal Development Ltd | Airway device |
EP4069213A1 (en) * | 2019-12-03 | 2022-10-12 | The USA, as represented by The Secretary, Department of Health and Human Services | Cyclooxygenase-2 inhibition for the treatment of saa-high asthma |
US20230073803A1 (en) * | 2019-12-16 | 2023-03-09 | Themis Medicare Limited | Pharmaceutical composition of cyclooxygenase - 2 inhibitors |
USD1025348S1 (en) | 2020-04-16 | 2024-04-30 | Intersurgical Ag | Airway device |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6034256A (en) * | 1997-04-21 | 2000-03-07 | G.D. Searle & Co. | Substituted benzopyran derivatives for the treatment of inflammation |
US5994379A (en) * | 1998-02-13 | 1999-11-30 | Merck Frosst Canada, Inc. | Bisaryl COX-2 inhibiting compounds, compositions and methods of use |
AU1930301A (en) * | 1999-12-08 | 2001-06-18 | Pharmacia Corporation | Valdecoxib compositions |
TWI256305B (en) * | 2000-08-18 | 2006-06-11 | Pharmacia Corp | Oral fast-melt pharmaceutical composition of a cyclooxygenase-2 inhibitor and process for preparing the same |
PT1429807E (pt) * | 2001-09-19 | 2007-05-31 | Altana Pharma Ag | Combinação de um nsaid e de um inibidor de pde-4 |
-
2004
- 2004-10-21 EP EP04795797A patent/EP1691797A2/en active Pending
- 2004-10-21 JP JP2006536743A patent/JP2007509154A/ja not_active Withdrawn
- 2004-10-21 BR BRPI0415753-2A patent/BRPI0415753A/pt not_active Application Discontinuation
- 2004-10-21 CA CA002542277A patent/CA2542277A1/en not_active Abandoned
- 2004-10-21 MX MXPA06004499A patent/MXPA06004499A/es unknown
- 2004-10-21 WO PCT/US2004/034685 patent/WO2005041864A2/en not_active Application Discontinuation
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8541456B2 (en) | 2005-03-08 | 2013-09-24 | Takeda Gmbh | Roflumilast for the treatment of diabetes mellitus type 2 |
Also Published As
Publication number | Publication date |
---|---|
EP1691797A2 (en) | 2006-08-23 |
MXPA06004499A (es) | 2006-06-27 |
WO2005041864A3 (en) | 2006-05-18 |
BRPI0415753A (pt) | 2006-12-19 |
WO2005041864A2 (en) | 2005-05-12 |
JP2007509154A (ja) | 2007-04-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
FZDE | Dead |