CA2540551A1 - Single nucleotide polymorphism analysis of highly polymorphic target sequences - Google Patents
Single nucleotide polymorphism analysis of highly polymorphic target sequences Download PDFInfo
- Publication number
- CA2540551A1 CA2540551A1 CA002540551A CA2540551A CA2540551A1 CA 2540551 A1 CA2540551 A1 CA 2540551A1 CA 002540551 A CA002540551 A CA 002540551A CA 2540551 A CA2540551 A CA 2540551A CA 2540551 A1 CA2540551 A1 CA 2540551A1
- Authority
- CA
- Canada
- Prior art keywords
- probe
- base
- nucleic acid
- group
- target
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
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- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
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| PCT/US2004/032265 WO2005035545A2 (en) | 2003-10-02 | 2004-09-30 | Single nucleotide polymorphism analysis of highly polymorphic target sequences |
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| PL1687609T3 (pl) * | 2003-10-28 | 2015-05-29 | Epoch Biosciences Inc | Sondy fluoroscencyjne do wykrywania DNA przez hybrydyzację o ulepszonej czułości i niskim tle |
| EP1896602A4 (en) * | 2005-06-09 | 2009-08-12 | Epoch Biosciences Inc | IMPROVED AMPLIFICATION PROCESSES ON PRIMER BASIS |
| JP4713514B2 (ja) * | 2006-02-20 | 2011-06-29 | エフ．ホフマン−ラ ロシュ アーゲー | 改善された標識試薬 |
| US9677123B2 (en) | 2006-03-15 | 2017-06-13 | Siemens Healthcare Diagnostics Inc. | Degenerate nucleobase analogs |
| WO2008067002A2 (en) * | 2006-09-11 | 2008-06-05 | Southern Research Institute | Azole nucleosides and use as inhibitors of rna and dna varial polymerases |
| US8180572B2 (en) * | 2007-10-25 | 2012-05-15 | Canon U.S. Life Sciences, Inc. | High-resolution melting analysis |
| US9534255B2 (en) | 2008-12-17 | 2017-01-03 | Life Technologies Corporation | Methods, compositions, and kits for detecting allelic variants |
| WO2010111682A2 (en) | 2009-03-27 | 2010-09-30 | Life Technologies Corporation | Methods, compositions, and kits for detecting allelic variants |
| CA2756871A1 (en) | 2009-03-31 | 2010-10-07 | Arqule, Inc. | Substituted heterocyclic compounds |
| CN101659952B (zh) * | 2009-07-14 | 2012-07-18 | 上海之江生物科技有限公司 | 锁核酸和小沟结合物共修饰核酸片段 |
| AU2010324860A1 (en) * | 2009-11-25 | 2012-06-14 | Dharmacon, Inc. | Minor groove binder (MGB)-oligonucleotide miRNAs antagonists |
| WO2012097353A1 (en) * | 2011-01-14 | 2012-07-19 | Life Technologies Corporation | Methods, compositions, and kits for detecting rare cells |
| US9085800B2 (en) | 2011-03-23 | 2015-07-21 | Elitech Holding B.V. | Functionalized 3-alkynyl pyrazolopyrimidine analogues as universal bases and methods of use |
| US8969003B2 (en) | 2011-03-23 | 2015-03-03 | Elitech Holding B.V. | Functionalized 3-alkynyl pyrazolopyrimidine analogues as universal bases and methods of use |
| JP2013081448A (ja) * | 2011-05-02 | 2013-05-09 | Arkray Inc | 遺伝子変異検出用プローブ |
| US9677142B2 (en) | 2011-05-24 | 2017-06-13 | Elitechgroup B.V. | Detection of methicillin-resistant Staphylococcus aureus |
| WO2014159063A1 (en) | 2013-03-14 | 2014-10-02 | Elitech Holding B.V. | Functionalized 3-alkynyl pyrazolopyrimidine analogues as universal bases and methods of use |
| WO2014160046A1 (en) * | 2013-03-14 | 2014-10-02 | The Trustees Of The University Of Pennsylvania | A method for detecting mutations in single cells or single molecules |
| ES2654631T3 (es) | 2013-05-13 | 2018-02-14 | Elitechgroup B.V. | PCR digital en gotas con sondas cortas de ranura menor |
| RS59991B1 (sr) * | 2013-08-08 | 2020-04-30 | Scripps Research Inst | Metoda enzimskog in vitro obeležavanja specifičnog za položaj nukleinskih kiselina uvođenjem neprirodnih nukleotida |
| US10100349B2 (en) * | 2013-09-30 | 2018-10-16 | President And Fellows Of Harvard College | Methods of determining polymorphisms |
| GB201317355D0 (en) * | 2013-10-01 | 2013-11-13 | Epistem Ltd | Mutation Analysis |
| JP2017538418A (ja) | 2014-12-12 | 2017-12-28 | エリテックグループ・ベスローテン・フェンノートシャップＥｌｉｔｅｃｈｇｒｏｕｐ Ｂ．Ｖ． | 抗生物質耐性細菌を検出する方法および組成物 |
| WO2016094162A1 (en) | 2014-12-12 | 2016-06-16 | Elitechgroup B.V. | Methods and compositions for detecting antibiotic resistant bacteria |
| NO344051B1 (en) * | 2017-05-04 | 2019-08-26 | Patogen As | Novel virus in Fish and Method for detection |
| IL271903B2 (en) | 2017-07-11 | 2025-04-01 | Synthorx Inc | Combination of unnatural nucleotides and methods therefor |
| SG11202000939PA (en) | 2017-08-03 | 2020-02-27 | Synthorx Inc | Cytokine conjugates for the treatment of proliferative and infectious diseases |
| US10677728B2 (en) | 2017-08-17 | 2020-06-09 | Elitechgroup B.V. | Duplex stabilizing fluorescence quenchers for nucleic acid probes |
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- 2004-09-30 EP EP04789416A patent/EP1670928A4/en not_active Withdrawn
- 2004-09-30 CA CA002540551A patent/CA2540551A1/en not_active Abandoned
- 2004-09-30 AU AU2004279810A patent/AU2004279810A1/en not_active Abandoned
- 2004-09-30 WO PCT/US2004/032265 patent/WO2005035545A2/en not_active Ceased
- 2004-09-30 JP JP2006534123A patent/JP2007510401A/ja active Pending
-
2008
- 2008-01-28 US US12/020,908 patent/US7718374B2/en not_active Expired - Lifetime
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| WO2005035545A3 (en) | 2005-07-28 |
| EP1670928A4 (en) | 2008-06-25 |
| US20050118623A1 (en) | 2005-06-02 |
| US7718374B2 (en) | 2010-05-18 |
| US20090087922A1 (en) | 2009-04-02 |
| US7348146B2 (en) | 2008-03-25 |
| EP1670928A2 (en) | 2006-06-21 |
| AU2004279810A1 (en) | 2005-04-21 |
| JP2007510401A (ja) | 2007-04-26 |
| WO2005035545A2 (en) | 2005-04-21 |
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