CA2525493C - Proteines de sang humain exprimees dans les semences d'oryza - Google Patents

Proteines de sang humain exprimees dans les semences d'oryza Download PDF

Info

Publication number
CA2525493C
CA2525493C CA2525493A CA2525493A CA2525493C CA 2525493 C CA2525493 C CA 2525493C CA 2525493 A CA2525493 A CA 2525493A CA 2525493 A CA2525493 A CA 2525493A CA 2525493 C CA2525493 C CA 2525493C
Authority
CA
Canada
Prior art keywords
protein
human blood
plant
blood protein
seeds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA2525493A
Other languages
English (en)
Other versions
CA2525493A1 (fr
Inventor
Ning Huang
Raymond L. Rodriquez
Frank E. Hagie
David M. Stalker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Invitria Inc
Original Assignee
Ventria Bioscience Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ventria Bioscience Inc filed Critical Ventria Bioscience Inc
Publication of CA2525493A1 publication Critical patent/CA2525493A1/fr
Application granted granted Critical
Publication of CA2525493C publication Critical patent/CA2525493C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • C07K14/75Fibrinogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/8107Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121Serpins
    • C07K14/8125Alpha-1-antitrypsin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/005Glycopeptides, glycoproteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

L'invention concerne des protéines sanguines produites dans des graines de monocotylédone et isolées de celles-ci en vue d'une utilisation dans des compositions thérapeutiques, ainsi que des méthodes de fabrication de ces protéines sanguines isolées et des compositions thérapeutiques les comprenant.
CA2525493A 2003-04-11 2003-04-11 Proteines de sang humain exprimees dans les semences d'oryza Expired - Lifetime CA2525493C (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2003/009209 WO2004099405A1 (fr) 2003-04-11 2003-04-11 Proteines sanguines humaines exprimees dans des graines de monocotyledone

Publications (2)

Publication Number Publication Date
CA2525493A1 CA2525493A1 (fr) 2004-11-18
CA2525493C true CA2525493C (fr) 2018-10-30

Family

ID=33434296

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2525493A Expired - Lifetime CA2525493C (fr) 2003-04-11 2003-04-11 Proteines de sang humain exprimees dans les semences d'oryza

Country Status (5)

Country Link
EP (1) EP1651760A4 (fr)
JP (1) JP2006522585A (fr)
AU (1) AU2003218396B2 (fr)
CA (1) CA2525493C (fr)
WO (1) WO2004099405A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109355291A (zh) * 2018-11-22 2019-02-19 深圳市作物分子设计育种研究院 一种植物胚乳特异性表达启动子pOsEnS93的鉴定和应用

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1711048A4 (fr) * 2003-12-23 2008-05-14 Ventria Bioscience Procedes permettant d'exprimer une proteine heterologue dans des graines vegetales a l'aide de promoteurs de proteines de graines de monocotyledone autres que des proteines de reserve
WO2006108830A2 (fr) * 2005-04-13 2006-10-19 Bayer Cropscience Sa Vegetaux transplastomiques exprimant l'$g(a)1-antitrypsine
WO2007134234A2 (fr) 2006-05-12 2007-11-22 Monsanto Technology Llc Procédés et compositions pour l'élaboration de plantes transgéniques sans marqueur
KR20110040895A (ko) * 2008-07-09 2011-04-20 프로피브릭스 비.브이. 재조합 섬유소원
CN102127164B (zh) * 2010-12-20 2013-01-30 武汉禾元生物科技有限公司 一种从水稻种子中提取重组人血清白蛋白的方法
CN102532254B (zh) 2010-12-24 2015-06-24 武汉禾元生物科技股份有限公司 一种从水稻种子中分离纯化重组人血清白蛋白的方法
CN102994514B (zh) * 2012-11-07 2015-06-10 武汉禾元生物科技股份有限公司 一种从水稻种子生产和分离纯化重组人抗胰蛋白酶(OsrAAT)的方法
CN103880947B (zh) 2012-12-21 2016-01-13 武汉禾元生物科技股份有限公司 一种分离纯化高纯度重组人血清白蛋白的层析方法
PT3044320T (pt) * 2013-09-11 2020-04-13 Impossible Foods Inc Secreção de polipéptidos contendo heme
PL3294762T3 (pl) 2015-05-11 2022-04-25 Impossible Foods Inc. Konstrukty ekspresyjne i sposoby inżynierii genetycznej drożdży metylotroficznych
KR20220004090A (ko) 2019-04-25 2022-01-11 임파서블 푸즈 인크. 헴-함유 단백질의 생산을 위한 균주 및 방법
WO2024003668A1 (fr) * 2022-06-29 2024-01-04 Moolec Science Limited Expression élevée de protéine héminique animale dans des plantes

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5693506A (en) * 1993-11-16 1997-12-02 The Regents Of The University Of California Process for protein production in plants
FR2736930B1 (fr) * 1995-07-17 1997-09-19 Biocem Procede de production, par des cellules vegetales, de proteines heminiques, proteines ainsi obtenues et produits contenant ces proteines
AU2002244071A1 (en) * 2001-02-14 2002-08-28 Ventria Bioscience Expression system for seed proteins

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109355291A (zh) * 2018-11-22 2019-02-19 深圳市作物分子设计育种研究院 一种植物胚乳特异性表达启动子pOsEnS93的鉴定和应用
CN109355291B (zh) * 2018-11-22 2022-01-18 深圳市作物分子设计育种研究院 一种植物胚乳特异性表达启动子pOsEnS93的鉴定和应用

Also Published As

Publication number Publication date
CA2525493A1 (fr) 2004-11-18
WO2004099405A1 (fr) 2004-11-18
AU2003218396B2 (en) 2008-09-04
EP1651760A1 (fr) 2006-05-03
AU2003218396A1 (en) 2004-11-26
JP2006522585A (ja) 2006-10-05
EP1651760A4 (fr) 2006-10-18

Similar Documents

Publication Publication Date Title
US8686225B2 (en) Monocot seed product comprising a human blood protein
US7718851B2 (en) Expression of human milk proteins in transgenic plants
US6991824B2 (en) Expression of human milk proteins in transgenic plants
CA2525493C (fr) Proteines de sang humain exprimees dans les semences d'oryza
US20100119691A1 (en) Expression of human milk proteins in transgenic plants
US20160076048A1 (en) Non-glycosylated transferrin expressed in monocots
AU2002250127B2 (en) Expression of human milk proteins in transgenic plants
US6127145A (en) Production of α1 -antitrypsin in plants
AU746826B2 (en) Production of mature proteins in plants
WO2002064750A2 (fr) Systeme d'expression de proteines de graines
CN101313071B (zh) 用于生产蛋白的转基因芦荟植物及其相关的方法
Miao et al. Plant bioreactors for pharmaceuticals
EP1272649A2 (fr) Expression et purification de polypeptides authentiques bioactifs issus de plantes
US20080010697A1 (en) Methods of Expressing Heterologous Protein in Plant Seeds Using Monocot Non Seed-Storage Protein Promoters
AU2007216827B2 (en) Expression of human milk proteins in transgenic plants
Sutliff et al. Production of α 1-antitrypsin in plants

Legal Events

Date Code Title Description
EEER Examination request
MKEX Expiry

Effective date: 20230411