CA2506684A1 - Epitopes immunogenes pour facteur de croissance fibroplastique 5 (fgf-5) presente par hla-a3 et hla-a2 - Google Patents
Epitopes immunogenes pour facteur de croissance fibroplastique 5 (fgf-5) presente par hla-a3 et hla-a2 Download PDFInfo
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- CA2506684A1 CA2506684A1 CA002506684A CA2506684A CA2506684A1 CA 2506684 A1 CA2506684 A1 CA 2506684A1 CA 002506684 A CA002506684 A CA 002506684A CA 2506684 A CA2506684 A CA 2506684A CA 2506684 A1 CA2506684 A1 CA 2506684A1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/50—Fibroblast growth factor [FGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
La présente invention se rapporte à des peptides que l'on utilise dans l'immunothérapie de tumeurs. Les peptides de cette invention sont dérivés de la séquence d'acides aminés d'un antigène associé au carcinome d'une cellule rénale, et du vecteur de croissance fibroplastique 5 (FGF-5). Selon une variante, le peptide est un épitope HLA-A3 (notamment NTYASPRFK). Selon une autre variante, le peptide est un épitope HLA-A2 (notamment MLSVLEIFAV). Les procédés de cette invention utilisent de tels peptides et leurs variants ou fusions afin de stimuler une réponse immunitaire chez un patient. Les peptides de cette invention peuvent être formulés sous forme de compositions pharmaceutiques en vue de leur administration chez un patient.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42792002P | 2002-11-19 | 2002-11-19 | |
| US60/427,920 | 2002-11-19 | ||
| PCT/US2003/037065 WO2004045555A2 (fr) | 2002-11-19 | 2003-11-19 | Epitopes immunogenes pour facteur de croissance fibroplastique 5 (fgf-5) presente par hla-a3 et hla-a2 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2506684A1 true CA2506684A1 (fr) | 2004-06-03 |
Family
ID=32326614
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002506684A Abandoned CA2506684A1 (fr) | 2002-11-19 | 2003-11-19 | Epitopes immunogenes pour facteur de croissance fibroplastique 5 (fgf-5) presente par hla-a3 et hla-a2 |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP1562622A2 (fr) |
| AU (1) | AU2003298677A1 (fr) |
| CA (1) | CA2506684A1 (fr) |
| WO (1) | WO2004045555A2 (fr) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001025271A2 (fr) * | 1999-10-02 | 2001-04-12 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Facteur de croissance des fibroblastes 5 (fgf-5) dans un antigene de leucocyte t associe aux tumeurs |
| US20020031805A1 (en) * | 1999-12-29 | 2002-03-14 | Conklin Darrell C. | Novel FGF homolog zFGF10 |
-
2003
- 2003-11-19 AU AU2003298677A patent/AU2003298677A1/en not_active Abandoned
- 2003-11-19 EP EP03796431A patent/EP1562622A2/fr not_active Withdrawn
- 2003-11-19 WO PCT/US2003/037065 patent/WO2004045555A2/fr not_active Application Discontinuation
- 2003-11-19 CA CA002506684A patent/CA2506684A1/fr not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1562622A2 (fr) | 2005-08-17 |
| AU2003298677A1 (en) | 2004-06-15 |
| WO2004045555A3 (fr) | 2004-08-26 |
| WO2004045555A2 (fr) | 2004-06-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |