CA2504751C - Methods for treating gastroesophageal reflux disease - Google Patents
Methods for treating gastroesophageal reflux disease Download PDFInfo
- Publication number
- CA2504751C CA2504751C CA2504751A CA2504751A CA2504751C CA 2504751 C CA2504751 C CA 2504751C CA 2504751 A CA2504751 A CA 2504751A CA 2504751 A CA2504751 A CA 2504751A CA 2504751 C CA2504751 C CA 2504751C
- Authority
- CA
- Canada
- Prior art keywords
- use according
- glucocorticoid receptor
- gastroesophageal reflux
- antagonist
- reflux disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/46—Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of glucocorticosteroids
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
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- Diabetes (AREA)
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- Neurosurgery (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US42419902P | 2002-11-05 | 2002-11-05 | |
| US60/424,199 | 2002-11-05 | ||
| PCT/US2003/035341 WO2004041215A2 (en) | 2002-11-05 | 2003-11-05 | Methods for treating gastroesophageal reflux disease |
Publications (2)
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| CA2504751A1 CA2504751A1 (en) | 2004-05-21 |
| CA2504751C true CA2504751C (en) | 2013-02-05 |
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| CA2504751A Expired - Fee Related CA2504751C (en) | 2002-11-05 | 2003-11-05 | Methods for treating gastroesophageal reflux disease |
| CA2504697A Expired - Fee Related CA2504697C (en) | 2002-11-05 | 2003-11-05 | Methods for treating migraine |
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| Application Number | Title | Priority Date | Filing Date |
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| CA2504697A Expired - Fee Related CA2504697C (en) | 2002-11-05 | 2003-11-05 | Methods for treating migraine |
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| US (2) | US7361646B2 (enExample) |
| EP (2) | EP1581234A4 (enExample) |
| JP (3) | JP2006508951A (enExample) |
| AU (2) | AU2003291314B2 (enExample) |
| CA (2) | CA2504751C (enExample) |
| WO (2) | WO2004041214A2 (enExample) |
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| US8569277B2 (en) | 2004-08-11 | 2013-10-29 | Palo Alto Investors | Methods of treating a subject for a condition |
| US8324192B2 (en) | 2005-11-12 | 2012-12-04 | The Regents Of The University Of California | Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract |
| US8497258B2 (en) | 2005-11-12 | 2013-07-30 | The Regents Of The University Of California | Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract |
| US8679545B2 (en) | 2005-11-12 | 2014-03-25 | The Regents Of The University Of California | Topical corticosteroids for the treatment of inflammatory diseases of the gastrointestinal tract |
| CA2649894A1 (en) * | 2006-05-02 | 2007-11-15 | Corcept Therapeutics, Inc. | The use of a glucocorticoid receptor ii antagonist to treat depression in patients taking il-2 |
| CA2676670C (en) | 2007-02-02 | 2012-03-13 | Pfizer Products Inc. | Tricyclic compounds, compositions, and methods |
| ES2626131T3 (es) * | 2007-10-17 | 2017-07-24 | Laboratoire Hra Pharma | Antagonistas del receptor de glucocorticoides tales como mifepristona para tratar el síndrome de Cushing |
| US20090123551A1 (en) * | 2007-11-13 | 2009-05-14 | Meritage Pharma, Inc. | Gastrointestinal delivery systems |
| US20100216754A1 (en) * | 2007-11-13 | 2010-08-26 | Meritage Pharma, Inc. | Compositions for the treatment of inflammation of the gastrointestinal tract |
| US20090143343A1 (en) * | 2007-11-13 | 2009-06-04 | Meritage Pharma, Inc. | Compositions for the treatment of inflammation of the gastrointestinal tract |
| KR101245604B1 (ko) | 2007-11-13 | 2013-03-21 | 메리테이지 파마, 인크. | 코르티코스테로이드 조성물 |
| US20090264392A1 (en) * | 2008-04-21 | 2009-10-22 | Meritage Pharma, Inc. | Treating eosinophilic esophagitis |
| WO2010144865A2 (en) * | 2009-06-12 | 2010-12-16 | Meritage Pharma, Inc. | Methods for treating gastrointestinal disorders |
| US10500216B2 (en) | 2011-11-18 | 2019-12-10 | Corcept Therapeutics, Inc. | Optimizing mifepristone absorption |
| US20150209374A1 (en) | 2014-01-29 | 2015-07-30 | Faro Owiesy | Composition and Method for Curing Migraine Headaches |
| US9943526B2 (en) | 2015-04-21 | 2018-04-17 | Corcept Therapeutics, Inc. | Optimizing mifepristone levels for cushing's patients |
| MX383318B (es) | 2015-08-13 | 2025-03-13 | Corcept Therapeutics Inc | Metodo para diagnosticar de manera diferencial el sindrome de cushing dependiente de la corticotropina. |
| CA3011728A1 (en) | 2016-01-19 | 2017-07-27 | Corcept Therapeutics, Inc. | Differential diagnosis of ectopic cushing's syndrome |
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| FR2576025B1 (fr) * | 1985-01-14 | 1987-01-23 | Roussel Uclaf | Nouveaux steroides substitues en position 10, leur procede et les intermediaires de preparation, leur application comme medicaments, les compositions pharmaceutiques les contenant |
| FR2598421B1 (fr) | 1986-05-06 | 1988-08-19 | Roussel Uclaf | Nouveaux produits 19-nor ou 19-nor d-homo steroides substitues en position 11b par un radical phenyle portant un radical alkynyle, leur procede de preparation, leur application comme medicaments et les compositions les renfermant |
| US5250529A (en) * | 1990-02-08 | 1993-10-05 | Kos Pharmaceuticals, Inc. | Method alleviating migraine headache with mast cell degranulation blocking agents |
| US5468741A (en) * | 1993-05-28 | 1995-11-21 | The Regents Of The University Of California | Use of low levels of mifepristone to treat leiomyomata |
| US5521166A (en) * | 1994-12-19 | 1996-05-28 | Ortho Pharmaceitical Corporation | Antiprogestin cyclophasic hormonal regimen |
| IL118974A (en) | 1995-08-17 | 2001-09-13 | Akzo Nobel Nv | History 11 - (Transformed Phenyl) - Astra - 4, 9 - Diane, their preparation and pharmaceutical preparations containing them |
| US5914129A (en) * | 1996-07-23 | 1999-06-22 | Mauskop; Alexander | Analgesic composition for treatment of migraine headaches |
| US5697112A (en) * | 1996-11-08 | 1997-12-16 | Glaxo Wellcome Inc. | Therapy pillow useful for treating gastroesophageal reflux disease (gerd) and other applications |
| US6166013A (en) * | 1998-07-30 | 2000-12-26 | Abbott Laboratories | Glucocortiocoid-selective agents |
| HUP0201243A3 (en) | 1999-04-30 | 2002-11-28 | Pfizer Prod Inc | Glucocorticoid receptor modulators, pharmaceutical compositions containing them and their use |
| IL139197A0 (en) * | 1999-10-29 | 2001-11-25 | Pfizer Prod Inc | Use of corticotropin releasing factor antagonists and related compositions |
| US6579898B2 (en) | 2001-03-01 | 2003-06-17 | Pfizer Inc. | Compositions having improved bioavailability |
| AU2002361861A1 (en) * | 2001-12-21 | 2003-07-30 | Rhode Island Hospital | SELECTIVE 11Beta-HSD INHIBITORS AND METHODS FOR USE THEREOF |
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- 2003-11-05 JP JP2004550521A patent/JP2006508951A/ja active Pending
- 2003-11-05 AU AU2003291314A patent/AU2003291314B2/en not_active Ceased
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| WO2004041214A3 (en) | 2004-11-11 |
| EP1567167A4 (en) | 2007-09-12 |
| WO2004041215A3 (en) | 2004-11-04 |
| CA2504697A1 (en) | 2004-05-21 |
| AU2003291314C1 (en) | 2004-06-07 |
| WO2004041215A2 (en) | 2004-05-21 |
| JP2006507311A (ja) | 2006-03-02 |
| CA2504751A1 (en) | 2004-05-21 |
| AU2003291314B2 (en) | 2007-07-26 |
| JP2006508951A (ja) | 2006-03-16 |
| AU2003291322A1 (en) | 2004-06-07 |
| US7361646B2 (en) | 2008-04-22 |
| EP1581234A4 (en) | 2007-09-12 |
| JP2011021044A (ja) | 2011-02-03 |
| CA2504697C (en) | 2012-03-13 |
| US20040132703A1 (en) | 2004-07-08 |
| EP1581234A2 (en) | 2005-10-05 |
| AU2003291322B2 (en) | 2008-09-25 |
| EP1567167A2 (en) | 2005-08-31 |
| AU2003291314A1 (en) | 2004-06-07 |
| US20040167110A1 (en) | 2004-08-26 |
| WO2004041214A2 (en) | 2004-05-21 |
| US8450379B2 (en) | 2013-05-28 |
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| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20201105 |