CA2504751C - Methods for treating gastroesophageal reflux disease - Google Patents
Methods for treating gastroesophageal reflux disease Download PDFInfo
- Publication number
- CA2504751C CA2504751C CA2504751A CA2504751A CA2504751C CA 2504751 C CA2504751 C CA 2504751C CA 2504751 A CA2504751 A CA 2504751A CA 2504751 A CA2504751 A CA 2504751A CA 2504751 C CA2504751 C CA 2504751C
- Authority
- CA
- Canada
- Prior art keywords
- use according
- glucocorticoid receptor
- gastroesophageal reflux
- antagonist
- reflux disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/46—Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of glucocorticosteroids
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Pain & Pain Management (AREA)
- Diabetes (AREA)
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- Neurology (AREA)
- Neurosurgery (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42419902P | 2002-11-05 | 2002-11-05 | |
| US60/424,199 | 2002-11-05 | ||
| PCT/US2003/035341 WO2004041215A2 (en) | 2002-11-05 | 2003-11-05 | Methods for treating gastroesophageal reflux disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2504751A1 CA2504751A1 (en) | 2004-05-21 |
| CA2504751C true CA2504751C (en) | 2013-02-05 |
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| Application Number | Title | Priority Date | Filing Date |
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| CA2504751A Expired - Fee Related CA2504751C (en) | 2002-11-05 | 2003-11-05 | Methods for treating gastroesophageal reflux disease |
| CA2504697A Expired - Fee Related CA2504697C (en) | 2002-11-05 | 2003-11-05 | Methods for treating migraine |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2504697A Expired - Fee Related CA2504697C (en) | 2002-11-05 | 2003-11-05 | Methods for treating migraine |
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| Country | Link |
|---|---|
| US (2) | US7361646B2 (OSRAM) |
| EP (2) | EP1567167A4 (OSRAM) |
| JP (3) | JP2006507311A (OSRAM) |
| AU (2) | AU2003291322B2 (OSRAM) |
| CA (2) | CA2504751C (OSRAM) |
| WO (2) | WO2004041215A2 (OSRAM) |
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| US8569277B2 (en) * | 2004-08-11 | 2013-10-29 | Palo Alto Investors | Methods of treating a subject for a condition |
| US8324192B2 (en) | 2005-11-12 | 2012-12-04 | The Regents Of The University Of California | Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract |
| US8497258B2 (en) | 2005-11-12 | 2013-07-30 | The Regents Of The University Of California | Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract |
| US8679545B2 (en) * | 2005-11-12 | 2014-03-25 | The Regents Of The University Of California | Topical corticosteroids for the treatment of inflammatory diseases of the gastrointestinal tract |
| JP2009535430A (ja) * | 2006-05-02 | 2009-10-01 | コーセプト セラピューティクス， インコーポレイテッド | Ｉｌ−２を摂取している患者における抑うつを処置するためのグルココルチコイドレセプターｉｉアンタゴニストの使用 |
| KR101107949B1 (ko) | 2007-02-02 | 2012-02-08 | 화이자 프로덕츠 인코포레이티드 | 트라이사이클릭 화합물 및 글루코코르티코이드 수용체 조절자로서의 이들의 용도 |
| EP2211845B1 (en) * | 2007-10-17 | 2017-02-22 | Laboratoire HRA Pharma | Glucocorticoid receptor antagonists such as mifepristone for treating cushing's syndrome |
| LT3354276T (lt) | 2007-11-13 | 2020-04-27 | Meritage Pharma, Inc. | Kompozicijos, skirtos skrandžio ir žarnyno uždegimo gydymui |
| US20090123551A1 (en) * | 2007-11-13 | 2009-05-14 | Meritage Pharma, Inc. | Gastrointestinal delivery systems |
| US9050368B2 (en) * | 2007-11-13 | 2015-06-09 | Meritage Pharma, Inc. | Corticosteroid compositions |
| US20100216754A1 (en) * | 2007-11-13 | 2010-08-26 | Meritage Pharma, Inc. | Compositions for the treatment of inflammation of the gastrointestinal tract |
| US20090264392A1 (en) * | 2008-04-21 | 2009-10-22 | Meritage Pharma, Inc. | Treating eosinophilic esophagitis |
| WO2010144865A2 (en) * | 2009-06-12 | 2010-12-16 | Meritage Pharma, Inc. | Methods for treating gastrointestinal disorders |
| US10500216B2 (en) | 2011-11-18 | 2019-12-10 | Corcept Therapeutics, Inc. | Optimizing mifepristone absorption |
| US20150209374A1 (en) | 2014-01-29 | 2015-07-30 | Faro Owiesy | Composition and Method for Curing Migraine Headaches |
| US9943526B2 (en) | 2015-04-21 | 2018-04-17 | Corcept Therapeutics, Inc. | Optimizing mifepristone levels for cushing's patients |
| CA2994422A1 (en) | 2015-08-13 | 2017-02-16 | Corcept Therapeutics, Inc. | Method for differentially diagnosing acth-dependent cushing's syndrome |
| MX2018008849A (es) | 2016-01-19 | 2019-01-31 | Corcept Therapeutics Inc | Diagnostico diferencial de sindrome de cushing ectopico. |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2576025B1 (fr) * | 1985-01-14 | 1987-01-23 | Roussel Uclaf | Nouveaux steroides substitues en position 10, leur procede et les intermediaires de preparation, leur application comme medicaments, les compositions pharmaceutiques les contenant |
| FR2598421B1 (fr) * | 1986-05-06 | 1988-08-19 | Roussel Uclaf | Nouveaux produits 19-nor ou 19-nor d-homo steroides substitues en position 11b par un radical phenyle portant un radical alkynyle, leur procede de preparation, leur application comme medicaments et les compositions les renfermant |
| US5250529A (en) * | 1990-02-08 | 1993-10-05 | Kos Pharmaceuticals, Inc. | Method alleviating migraine headache with mast cell degranulation blocking agents |
| US5468741A (en) * | 1993-05-28 | 1995-11-21 | The Regents Of The University Of California | Use of low levels of mifepristone to treat leiomyomata |
| US5521166A (en) * | 1994-12-19 | 1996-05-28 | Ortho Pharmaceitical Corporation | Antiprogestin cyclophasic hormonal regimen |
| IL118974A (en) * | 1995-08-17 | 2001-09-13 | Akzo Nobel Nv | History 11 - (Transformed Phenyl) - Astra - 4, 9 - Diane, their preparation and pharmaceutical preparations containing them |
| US5914129A (en) * | 1996-07-23 | 1999-06-22 | Mauskop; Alexander | Analgesic composition for treatment of migraine headaches |
| US5697112A (en) * | 1996-11-08 | 1997-12-16 | Glaxo Wellcome Inc. | Therapy pillow useful for treating gastroesophageal reflux disease (gerd) and other applications |
| US6166013A (en) * | 1998-07-30 | 2000-12-26 | Abbott Laboratories | Glucocortiocoid-selective agents |
| OA11877A (en) * | 1999-04-30 | 2006-03-29 | Pfizer Prod Inc | Glucocorticoid receptor modulators. |
| CO5271670A1 (es) * | 1999-10-29 | 2003-04-30 | Pfizer Prod Inc | Antagonistas del factor de liberacion de corticitropina y composiciones relacionadas |
| US6579898B2 (en) | 2001-03-01 | 2003-06-17 | Pfizer Inc. | Compositions having improved bioavailability |
| US20030148987A1 (en) * | 2001-12-21 | 2003-08-07 | Morris David J. | Selective 11beta-HSD inhibitors and methods of use thereof |
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2003
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- 2003-11-05 JP JP2004550521A patent/JP2006508951A/ja active Pending
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- 2003-11-05 AU AU2003291322A patent/AU2003291322B2/en not_active Ceased
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- 2003-11-05 EP EP03768706A patent/EP1581234A4/en not_active Withdrawn
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- 2003-11-05 AU AU2003291314A patent/AU2003291314B2/en not_active Ceased
- 2003-11-05 US US10/703,069 patent/US8450379B2/en active Active
- 2003-11-05 WO PCT/US2003/035341 patent/WO2004041215A2/en not_active Ceased
- 2003-11-05 WO PCT/US2003/035328 patent/WO2004041214A2/en not_active Ceased
- 2003-11-05 CA CA2504697A patent/CA2504697C/en not_active Expired - Fee Related
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2010
- 2010-11-05 JP JP2010249214A patent/JP2011021044A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2011021044A (ja) | 2011-02-03 |
| US20040167110A1 (en) | 2004-08-26 |
| WO2004041215A3 (en) | 2004-11-04 |
| WO2004041214A3 (en) | 2004-11-11 |
| EP1581234A4 (en) | 2007-09-12 |
| JP2006507311A (ja) | 2006-03-02 |
| CA2504697C (en) | 2012-03-13 |
| AU2003291314B2 (en) | 2007-07-26 |
| AU2003291314C1 (en) | 2004-06-07 |
| EP1581234A2 (en) | 2005-10-05 |
| US20040132703A1 (en) | 2004-07-08 |
| CA2504697A1 (en) | 2004-05-21 |
| AU2003291322B2 (en) | 2008-09-25 |
| EP1567167A2 (en) | 2005-08-31 |
| JP2006508951A (ja) | 2006-03-16 |
| US7361646B2 (en) | 2008-04-22 |
| AU2003291314A1 (en) | 2004-06-07 |
| WO2004041214A2 (en) | 2004-05-21 |
| CA2504751A1 (en) | 2004-05-21 |
| WO2004041215A2 (en) | 2004-05-21 |
| US8450379B2 (en) | 2013-05-28 |
| AU2003291322A1 (en) | 2004-06-07 |
| EP1567167A4 (en) | 2007-09-12 |
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| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20201105 |