CA2504532C - Botulinum neurotoxin b receptors and use thereof - Google Patents
Botulinum neurotoxin b receptors and use thereof Download PDFInfo
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- CA2504532C CA2504532C CA2504532A CA2504532A CA2504532C CA 2504532 C CA2504532 C CA 2504532C CA 2504532 A CA2504532 A CA 2504532A CA 2504532 A CA2504532 A CA 2504532A CA 2504532 C CA2504532 C CA 2504532C
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/02—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
Landscapes
- Health & Medical Sciences (AREA)
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- Neurosurgery (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- External Artificial Organs (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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| US42295102P | 2002-10-31 | 2002-10-31 | |
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| US49812803P | 2003-08-27 | 2003-08-27 | |
| US60/498,128 | 2003-08-27 | ||
| PCT/US2003/034348 WO2005016233A2 (en) | 2002-10-31 | 2003-10-28 | Botulinum neurotoxin b receptors and use thereof |
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| CA2504532A1 CA2504532A1 (en) | 2005-02-24 |
| CA2504532C true CA2504532C (en) | 2014-09-16 |
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| EP (1) | EP1578382B1 (enExample) |
| JP (2) | JP2006512090A (enExample) |
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| EP1578382B1 (en) * | 2002-10-31 | 2009-09-09 | Wisconsin Alumni Research Foundation | Botulinum neurotoxin b receptors and use thereof |
| US7341843B2 (en) * | 2003-04-11 | 2008-03-11 | Allergan, Inc. | Botulinum toxin A peptides and methods of predicting and reducing immunoresistance to botulinum toxin therapy |
| WO2006113648A2 (en) * | 2005-04-18 | 2006-10-26 | University Of Massachusetts | Hn-33 compositions and methods |
| DE102005019302A1 (de) | 2005-04-26 | 2006-11-16 | Toxogen Gmbh | Carrier zum Targeting von Nervenzellen |
| US7985554B2 (en) | 2005-10-14 | 2011-07-26 | Wisconsin Alumni Research Foundation | Botulinum neurotoxin A receptor and the use thereof |
| DE102005051789B4 (de) | 2005-10-28 | 2014-08-07 | Toxogen Gmbh | Der Botulinus Neurotoxin A Proteinrezeptor und seine Anwendungen |
| CN101932936B (zh) | 2007-09-14 | 2016-04-27 | 拜奥麦迪逊公司 | 利用切割序列和间隔子的共振能量转移测定 |
| US10908146B2 (en) | 2011-06-01 | 2021-02-02 | Biomadison, Inc. | Compositions and methods for improving sensitivity in cell based assays |
| US9303285B2 (en) | 2012-01-04 | 2016-04-05 | Biomadison, Inc. | Methods and compounds for increasing sensitivity of botulinum assays |
| US12422428B2 (en) | 2011-06-01 | 2025-09-23 | Biomadison, Inc. | Compositions and methods for cell-based assays |
| LT2715355T (lt) | 2011-06-01 | 2017-06-12 | Biomadison, Inc. | Ne fret (fluorescencijos rezonansinės energijos perdavimas) būdu atliekamas botulino tyrimas |
| US11325954B2 (en) | 2011-06-01 | 2022-05-10 | Biomadison, Inc. | Compositions and methods for stability testing of botulinum toxin |
| WO2015021433A1 (en) | 2013-08-09 | 2015-02-12 | Biomadison, Inc. | Botulinum toxin assay with improved sensitivity |
| JPWO2023210585A1 (enExample) * | 2022-04-25 | 2023-11-02 |
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| US6994995B1 (en) * | 2001-03-16 | 2006-02-07 | Lexicon Genetics Incorporated | Human synaptotagmin and polynucleotides encoding the same |
| US8022172B2 (en) * | 2001-08-28 | 2011-09-20 | Allergan, Inc. | Luminescence resonance energy transfer (LRET) assays for clostridial toxin activity |
| US7176278B2 (en) * | 2001-08-30 | 2007-02-13 | Biorexis Technology, Inc. | Modified transferrin fusion proteins |
| EP1578382B1 (en) * | 2002-10-31 | 2009-09-09 | Wisconsin Alumni Research Foundation | Botulinum neurotoxin b receptors and use thereof |
| EP1751284A4 (en) * | 2003-12-19 | 2010-01-13 | Wisconsin Alumni Res Found | METHOD AND COMPOSITIONS FOR DETECTING BOTULINUM NEUROTOXINE |
| EP1920248B1 (en) * | 2005-04-05 | 2010-09-29 | Allergan, Inc. | Clostridial toxin activity assays |
| AU2006299933A1 (en) * | 2005-08-02 | 2007-04-19 | Planet Biotechnology, Inc. | Improved chimeric toxin receptor proteins and chimeric toxin receptor proteins for treatment and prevention of anthrax |
| US7985554B2 (en) * | 2005-10-14 | 2011-07-26 | Wisconsin Alumni Research Foundation | Botulinum neurotoxin A receptor and the use thereof |
| WO2013011055A1 (en) * | 2011-07-19 | 2013-01-24 | ETH Zürich | Means and methods for determining clostridial neurotoxins |
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2003
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- 2003-10-28 DE DE60329225T patent/DE60329225D1/de not_active Expired - Lifetime
- 2003-10-28 CA CA2504532A patent/CA2504532C/en not_active Expired - Fee Related
- 2003-10-28 ES ES03816739T patent/ES2333319T3/es not_active Expired - Lifetime
- 2003-10-28 WO PCT/US2003/034348 patent/WO2005016233A2/en not_active Ceased
- 2003-10-28 JP JP2005507928A patent/JP2006512090A/ja active Pending
- 2003-10-28 AU AU2003304419A patent/AU2003304419A1/en not_active Abandoned
- 2003-10-28 AT AT03816739T patent/ATE442161T1/de not_active IP Right Cessation
- 2003-10-28 US US10/695,577 patent/US20040191887A1/en not_active Abandoned
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- 2005-04-10 IL IL167943A patent/IL167943A/en unknown
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2009
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2011
- 2011-10-26 US US13/281,501 patent/US8617573B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1578382A4 (en) | 2007-08-29 |
| EP1578382B1 (en) | 2009-09-09 |
| US8617573B2 (en) | 2013-12-31 |
| WO2005016233A3 (en) | 2005-08-18 |
| EP1578382A2 (en) | 2005-09-28 |
| US20120082672A1 (en) | 2012-04-05 |
| ES2333319T3 (es) | 2010-02-19 |
| JP2006512090A (ja) | 2006-04-13 |
| CA2504532A1 (en) | 2005-02-24 |
| ATE442161T1 (de) | 2009-09-15 |
| AU2003304419A1 (en) | 2005-03-07 |
| AU2003304419A8 (en) | 2005-03-07 |
| WO2005016233A2 (en) | 2005-02-24 |
| US20040191887A1 (en) | 2004-09-30 |
| DE60329225D1 (de) | 2009-10-22 |
| IL167943A (en) | 2010-12-30 |
| JP2010006833A (ja) | 2010-01-14 |
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