CA2504042A1 - Procedes, substances et materiel permettant d'examiner des voies associees a la progression de glioblastome - Google Patents

Procedes, substances et materiel permettant d'examiner des voies associees a la progression de glioblastome Download PDF

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Publication number
CA2504042A1
CA2504042A1 CA002504042A CA2504042A CA2504042A1 CA 2504042 A1 CA2504042 A1 CA 2504042A1 CA 002504042 A CA002504042 A CA 002504042A CA 2504042 A CA2504042 A CA 2504042A CA 2504042 A1 CA2504042 A1 CA 2504042A1
Authority
CA
Canada
Prior art keywords
leu
ser
lys
glu
ala
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002504042A
Other languages
English (en)
Inventor
Paul S. Mischel
Charles L. Sawyers
Bradley L. Smith
Katherine Crosby
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
Cell Signaling Technology Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2504042A1 publication Critical patent/CA2504042A1/fr
Abandoned legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5748—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving oncogenic proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

L'invention concerne des procédés d'examen et/ou d'évaluation quantitative de voies biochimiques qui sont déréglées dans des états pathologiques tels que le cancer. L'invention concerne également des agents réactifs et des trousses conçus pour effectuer ces procédés.
CA002504042A 2002-11-05 2003-11-05 Procedes, substances et materiel permettant d'examiner des voies associees a la progression de glioblastome Abandoned CA2504042A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42377702P 2002-11-05 2002-11-05
US60/423,777 2002-11-05
PCT/US2003/035115 WO2004044218A2 (fr) 2002-11-05 2003-11-05 Procedes, substances et materiel permettant d'examiner des voies associees a la progression de glioblastome

Publications (1)

Publication Number Publication Date
CA2504042A1 true CA2504042A1 (fr) 2004-05-27

Family

ID=32312710

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002504042A Abandoned CA2504042A1 (fr) 2002-11-05 2003-11-05 Procedes, substances et materiel permettant d'examiner des voies associees a la progression de glioblastome

Country Status (8)

Country Link
US (1) US20040106141A1 (fr)
EP (1) EP1567860A4 (fr)
JP (2) JP2006505793A (fr)
AU (1) AU2003291736A1 (fr)
CA (1) CA2504042A1 (fr)
DE (1) DE03768629T1 (fr)
ES (1) ES2245619T1 (fr)
WO (1) WO2004044218A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11821043B2 (en) 2017-08-17 2023-11-21 Nantomics Llc Dynamic changes in circulating free RNA of neural tumors

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006052249A1 (fr) * 2004-11-08 2006-05-18 The Regents Of The University Of California Procedes impliquant la voie de signalisation pi3k/akt dans des gliomes et des cancers de la prostate
WO2005007687A1 (fr) * 2003-07-09 2005-01-27 Dana-Farber Cancer Institute, Inc Compositions et procedes de modulation du declenchement folliculaire ovarien
EP1709449A1 (fr) * 2003-12-22 2006-10-11 Novartis AG Biomarqueurs pour la sensibilite de maladies proliferantes aux inhibiteurs mtor
US20080113874A1 (en) * 2004-01-23 2008-05-15 The Regents Of The University Of Colorado Gefitinib sensitivity-related gene expression and products and methods related thereto
WO2005070020A2 (fr) * 2004-01-23 2005-08-04 The Regents Of The University Of Colorado Expression genique relative a la sensibilite au gefitinib, produits et procedes associes
ES2677562T3 (es) * 2004-05-27 2018-08-03 The Regents Of The University Of Colorado Métodos para la predicción del resultado clínico para inhibidores del receptor del factor de crecimiento epidérmico para pacientes de cáncer
WO2006074392A2 (fr) * 2005-01-06 2006-07-13 Genentech, Inc. Procedes de pronostic, de diagnostic et de traitement du cancer
AU2006210837B2 (en) * 2005-01-31 2012-07-12 Genentech, Inc. Anti-EphB2 antibodies and methods using same
BRPI0608039A2 (pt) * 2005-03-11 2009-06-16 Univ Colorado células cancerìgenas sensìveis aos inibidores da histona deacetilase
WO2006122053A2 (fr) * 2005-05-09 2006-11-16 Ariad Gene Therapeutics, Inc. Biomarqueurs permettant d'evaluer la probabilite selon laquelle une tumeur est sensible a un inhibiteur de mtor
WO2007013997A2 (fr) * 2005-07-22 2007-02-01 H. Lee Moffitt Cancer Center And Research Institute Inhibition de la voie raf/mek/p-erk pour traiter le cancer
AU2006278456A1 (en) * 2005-08-03 2007-02-15 Ventana Medical Systems, Inc. Predictive methods for cancer chemotherapy
EP2290361A1 (fr) * 2006-02-16 2011-03-02 Ventana Medical Systems, Inc. Procédés pour sélectionner un traitment du carcinome colorectal
AU2012200691B2 (en) * 2006-02-16 2013-07-04 Ventana Medical Systems, Inc. Reagents and methods for cancer prognosis and pathological staging
WO2007106432A2 (fr) * 2006-03-10 2007-09-20 George Mason Intellectual Properties, Inc. Statut du recepteur de l'egf pour le traitement des maladies
US20090018142A9 (en) * 2006-05-02 2009-01-15 Zhengping Zhuang Use of phosphatases to treat tumors overexpressing N-CoR
AU2007248424B2 (en) * 2006-05-05 2013-04-18 Historx, Inc. Immunohistochemical methods for determining signal transduction activity in tumors
JP4795203B2 (ja) * 2006-11-13 2011-10-19 シスメックス株式会社 アンスラサイクリン系抗癌剤の感受性判定方法及びそのシステム
CN103788108B (zh) 2007-02-06 2017-04-12 利克斯特生物技术公司 氧杂双环庚烷和氧杂双环庚烯，它们的制备及用途
ES2526211T3 (es) * 2007-07-13 2015-01-08 Nestec S.A. Selección de fármacos para la terapia del cáncer de pulmón utilizando matrices basadas en anticuerpos
CA2718472A1 (fr) * 2007-08-03 2009-02-12 Lixte Biotechnology, Inc. Utilisation de phosphates pour traiter des neuroblastomes et des medulloblastomes
WO2009045440A1 (fr) 2007-10-01 2009-04-09 Lixte Biotechnology Holdings, Inc. Inhibiteurs de hdac
EP2271775A4 (fr) * 2008-04-08 2011-09-07 Nuclea Biomarkers Llc Panel de biomarqueurs pour la prédiction d'un cancer colorectal récurrent
WO2010014141A1 (fr) * 2008-08-01 2010-02-04 Lixte Biotechnology, Inc. Procédés de régulation de la mitose cellulaire par inhibition de la phosphatase de sérine/thréonine
AU2009277086B2 (en) * 2008-08-01 2015-12-10 Lixte Biotechnology, Inc. Neuroprotective agents for the prevention and treatment of neurodegenerative diseases
US8227473B2 (en) 2008-08-01 2012-07-24 Lixte Biotechnology, Inc. Oxabicycloheptanes and oxabicycloheptenes, their preparation and use
WO2010147612A1 (fr) 2009-06-18 2010-12-23 Lixte Biotechnology, Inc. Procédés de modulation de la régulation cellulaire par inhibition de p53
AU2010204741B2 (en) * 2009-01-14 2016-01-07 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Ratio based biomarkers and methods of use thereof
WO2011050351A2 (fr) * 2009-10-23 2011-04-28 The Translational Genomics Research Institute Procédés et trousses utilisés dans le cadre de l'identification du glioblastome
CA2787048C (fr) * 2010-01-13 2021-06-22 Wyeth Llc Point de decoupage dans l'expression de la proteine pten qui identifie avec precision les tumeurs et qui permet de predire la reponse medicamenteuse a un inhibiteur de pan-erbb
WO2012145426A1 (fr) 2011-04-18 2012-10-26 The Trustees Of Columbia University In The City Of New York Procédés pour traiter un cancer utilisant la cyclosporine et des dérivés de cyclosporine
CA2858688A1 (fr) 2011-12-08 2013-06-13 Five3 Genomics, Llc Chromosomes minuscules doubles contenant mdm2 et procedes associes
AU2014251087B2 (en) 2013-04-09 2019-05-02 Lixte Biotechnology, Inc. Formulations of oxabicycloheptanes and oxabicycloheptenes
US10941194B2 (en) 2015-01-22 2021-03-09 The Regents Of The University Of California Methods of diagnosing and treating autism spectrum disorders

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8479498A (en) * 1997-07-08 1999-02-08 Cold Spring Harbor Laboratory Dual specificity phosphatase and methods of use
US6020199A (en) * 1999-07-21 2000-02-01 Isis Pharmaceuticals Inc. Antisense modulation of PTEN expression
CA2478981A1 (fr) * 2002-03-21 2003-10-02 Sunesis Pharmaceuticals, Inc. Identification d'inhibiteurs de kinase
AU2003223495A1 (en) * 2002-04-05 2003-10-27 Cell Signaling Technology, Inc. Molecular profiling of disease and therapeutic response using phospho-specific antibodies

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11821043B2 (en) 2017-08-17 2023-11-21 Nantomics Llc Dynamic changes in circulating free RNA of neural tumors

Also Published As

Publication number Publication date
DE03768629T1 (de) 2006-01-26
WO2004044218A2 (fr) 2004-05-27
JP2006505793A (ja) 2006-02-16
EP1567860A4 (fr) 2006-05-10
AU2003291736A1 (en) 2004-06-03
JP2009115817A (ja) 2009-05-28
AU2003291736A8 (en) 2004-06-03
EP1567860A2 (fr) 2005-08-31
WO2004044218A3 (fr) 2004-12-02
US20040106141A1 (en) 2004-06-03
ES2245619T1 (es) 2006-01-16

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued