CA2501874A1 - Treating androgen decline in aging male (adam)-associated conditions with sarms - Google Patents
Treating androgen decline in aging male (adam)-associated conditions with sarms Download PDFInfo
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- CA2501874A1 CA2501874A1 CA002501874A CA2501874A CA2501874A1 CA 2501874 A1 CA2501874 A1 CA 2501874A1 CA 002501874 A CA002501874 A CA 002501874A CA 2501874 A CA2501874 A CA 2501874A CA 2501874 A1 CA2501874 A1 CA 2501874A1
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- sarm
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Classifications
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
- C07K14/721—Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
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- A—HUMAN NECESSITIES
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- A61P13/08—Drugs for disorders of the urinary system of the prostate
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
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- Molecular Biology (AREA)
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- Orthopedic Medicine & Surgery (AREA)
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- Gastroenterology & Hepatology (AREA)
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- Toxicology (AREA)
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- Urology & Nephrology (AREA)
- Gynecology & Obstetrics (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41833602P | 2002-10-16 | 2002-10-16 | |
| US60/418,336 | 2002-10-16 | ||
| PCT/US2003/032513 WO2004035739A2 (en) | 2002-10-16 | 2003-10-14 | Treating androgen decline in aging male (adam)-associated conditions with sarms |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2501874A1 true CA2501874A1 (en) | 2004-04-29 |
Family
ID=32107914
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002501874A Abandoned CA2501874A1 (en) | 2002-10-16 | 2003-10-14 | Treating androgen decline in aging male (adam)-associated conditions with sarms |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20050080054A1 (enExample) |
| EP (1) | EP1558233A2 (enExample) |
| JP (1) | JP2006505564A (enExample) |
| CN (1) | CN1726020A (enExample) |
| AU (1) | AU2003287079A1 (enExample) |
| CA (1) | CA2501874A1 (enExample) |
| IL (1) | IL168046A0 (enExample) |
| TW (1) | TW200502250A (enExample) |
| WO (1) | WO2004035739A2 (enExample) |
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| US8445534B2 (en) | 2000-08-24 | 2013-05-21 | University Of Tennessee Research Foundation | Treating androgen decline in aging male (ADAM)-associated conditions with SARMs |
| US20060019931A1 (en) * | 2003-10-14 | 2006-01-26 | Dalton James T | Treating bone-related disorders with selective androgen receptor modulators |
| US20060276539A1 (en) * | 2002-10-16 | 2006-12-07 | Dalton James T | Treating Androgen Decline in Aging Male (ADAM)- associated conditions with SARMS |
| US8309603B2 (en) | 2004-06-07 | 2012-11-13 | University Of Tennessee Research Foundation | SARMs and method of use thereof |
| FI20030958A0 (fi) * | 2003-06-27 | 2003-06-27 | Orion Corp | Uusia yhdisteitä |
| DE602005024274D1 (de) | 2004-07-16 | 2010-12-02 | Sunesis Pharmaceuticals Inc | Als aurora-kinase-inhibitoren nutzbare thienopyrimidine |
| CA2626337C (en) | 2005-10-19 | 2015-12-29 | Chavah Pty Ltd | Reduction of side effects from aromatase inhibitors used for treating breast cancer |
| US9730908B2 (en) | 2006-08-24 | 2017-08-15 | University Of Tennessee Research Foundation | SARMs and method of use thereof |
| US9844528B2 (en) | 2006-08-24 | 2017-12-19 | University Of Tennessee Research Foundation | SARMs and method of use thereof |
| US10010521B2 (en) | 2006-08-24 | 2018-07-03 | University Of Tennessee Research Foundation | SARMs and method of use thereof |
| US8791158B2 (en) | 2010-01-11 | 2014-07-29 | Gtx, Inc. | Methods of treating meibomian gland dysfunction |
| JP6055215B2 (ja) | 2012-06-29 | 2016-12-27 | キーサイト テクノロジーズ， インク． | インピーダンス測定方法及び測定装置 |
| CA2965372C (en) | 2014-10-22 | 2023-09-05 | Havah Therapeutics Pty Ltd | Methods of reducing mammographic breast density and/or breast cancer risk |
| CA3002562A1 (en) | 2015-10-22 | 2017-04-27 | Havah Therapeutics Pty Ltd | Methods of reducing mammographic breast density and/or breast cancer risk |
| CN114599369B (zh) | 2019-06-03 | 2026-02-10 | 哈瓦赫治疗有限公司 | 用于递送雄激素剂和芳香酶抑制剂的药物制剂和系统以及使用方法 |
| CN122228246A (zh) * | 2023-11-16 | 2026-06-16 | 恩多凯医药科技（北京）有限公司 | 神经活性雄激素受体调节剂及其用途 |
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| US3875229A (en) * | 1972-11-24 | 1975-04-01 | Schering Corp | Substituted carboxanilides |
| US4139638A (en) * | 1976-09-23 | 1979-02-13 | Schering Corporation | Methods for the treatment of hirsutism |
| DE2862100D1 (en) * | 1977-10-12 | 1983-01-05 | Ici Plc | Acylanilides, process for their manufacture and pharmaceutical and veterinary compositions containing them |
| US4191775A (en) * | 1977-12-15 | 1980-03-04 | Imperial Chemical Industries Limited | Amide derivatives |
| NZ197008A (en) * | 1980-05-22 | 1984-10-19 | Ici Ltd | Acylanilide derivatives and pharmaceutical compositions |
| JPS57171904A (en) * | 1981-04-15 | 1982-10-22 | Mitsubishi Petrochem Co Ltd | Tri- or tetra-substituted phenoxycarboxylic acid anilide type herbicide |
| DE3372965D1 (en) * | 1982-07-23 | 1987-09-17 | Ici Plc | Amide derivatives |
| GB8617652D0 (en) * | 1986-07-18 | 1986-08-28 | Ici Plc | Acylanilide derivatives |
| US5162504A (en) * | 1988-06-03 | 1992-11-10 | Cytogen Corporation | Monoclonal antibodies to a new antigenic marker in epithelial prostatic cells and serum of prostatic cancer patients |
| US5776923A (en) * | 1993-01-19 | 1998-07-07 | Endorecherche, Inc. | Method of treating or preventing osteoporosis by adminstering dehydropiandrosterone |
| US5609849A (en) * | 1994-03-11 | 1997-03-11 | The Trustees Of The University Of Pennsylvania | Serotonin (5-HT1A) receptor ligands and imaging agents |
| US5656651A (en) * | 1995-06-16 | 1997-08-12 | Biophysica Inc. | Androgenic directed compositions |
| US6017924A (en) * | 1996-06-27 | 2000-01-25 | Ligand Pharmaceuticals Incorporated | Androgen receptor modulator compounds and methods |
| US6569896B2 (en) * | 2000-08-24 | 2003-05-27 | The University Of Tennessee Research Corporation | Selective androgen receptor modulators and methods of use thereof |
| US6071957A (en) * | 1996-11-27 | 2000-06-06 | The University Of Tennessee Research Corporation | Irreversible non-steroidal antagonist compound and its use in the treatment of prostate cancer |
| AU7604798A (en) * | 1997-05-30 | 1998-12-30 | University Of Tennessee Research Corporation, The | Non-steroidal agonist compounds and their use in male hormone therapy |
| WO1998055153A1 (en) * | 1997-06-04 | 1998-12-10 | The University Of Tennessee Research Corporation | Non-steroidal radiolabeled agonist/antagonist compounds and their use in prostate cancer imaging |
| IL154425A0 (en) * | 2000-08-24 | 2003-09-17 | Univ Tennessee Res H Corp | Selective androgen receptor modulators and methods of use thereof |
| US7026500B2 (en) * | 2000-08-24 | 2006-04-11 | University Of Tennessee Research Foundation | Halogenated selective androgen receptor modulators and methods of use thereof |
| US8008348B2 (en) * | 2001-12-06 | 2011-08-30 | University Of Tennessee Research Foundation | Treating muscle wasting with selective androgen receptor modulators |
| US7645898B2 (en) * | 2000-08-24 | 2010-01-12 | University Of Tennessee Research Foundation | Selective androgen receptor modulators and method of use thereof |
| US20060019931A1 (en) * | 2003-10-14 | 2006-01-26 | Dalton James T | Treating bone-related disorders with selective androgen receptor modulators |
| PT1463497E (pt) * | 2001-12-06 | 2011-12-20 | Gtx Inc | Tratamento do desgaste muscular com moduladores selectivos do receptor de androgénios |
| US20070161608A1 (en) * | 2001-12-06 | 2007-07-12 | Dalton James T | Selective androgen receptor modulators for treating muscle wasting |
| US20070066568A1 (en) * | 2005-08-31 | 2007-03-22 | Dalton James T | Treating renal disease, burns, wounds and spinal cord injury with selective androgen receptor modulators |
| CA2689080C (en) * | 2002-02-07 | 2011-07-05 | University Of Tennessee Research Foundation | Treating benign prostate hyperplasia with sarms |
| AU2003287075A1 (en) * | 2002-10-15 | 2004-05-04 | Gtx, Inc. | Treating obesity with selective androgen receptor modulators |
| EP1594490A4 (en) * | 2003-01-22 | 2006-03-22 | Gtx Inc | TREATMENT OF WOMEN ANDROGEN DISEASE ASSOCIATED DISORDERS (ADIF) USING ANDROGENIC RECEPTOR MODULATORS (SARM) |
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- 2003-10-14 CN CNA2003801063099A patent/CN1726020A/zh active Pending
- 2003-10-14 JP JP2004544891A patent/JP2006505564A/ja active Pending
- 2003-10-14 CA CA002501874A patent/CA2501874A1/en not_active Abandoned
- 2003-10-14 EP EP03777600A patent/EP1558233A2/en not_active Withdrawn
- 2003-10-14 US US10/683,161 patent/US20050080054A1/en not_active Abandoned
- 2003-10-14 WO PCT/US2003/032513 patent/WO2004035739A2/en not_active Ceased
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- 2003-10-16 TW TW092128721A patent/TW200502250A/zh unknown
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Also Published As
| Publication number | Publication date |
|---|---|
| JP2006505564A (ja) | 2006-02-16 |
| US20050080054A1 (en) | 2005-04-14 |
| EP1558233A2 (en) | 2005-08-03 |
| TW200502250A (en) | 2005-01-16 |
| WO2004035739A3 (en) | 2004-09-30 |
| WO2004035739A2 (en) | 2004-04-29 |
| CN1726020A (zh) | 2006-01-25 |
| IL168046A0 (en) | 2009-02-11 |
| AU2003287079A1 (en) | 2004-05-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |