CA2501089C - 4-methylhexanoic kahalaide f compound - Google Patents
4-methylhexanoic kahalaide f compound Download PDFInfo
- Publication number
- CA2501089C CA2501089C CA2501089A CA2501089A CA2501089C CA 2501089 C CA2501089 C CA 2501089C CA 2501089 A CA2501089 A CA 2501089A CA 2501089 A CA2501089 A CA 2501089A CA 2501089 C CA2501089 C CA 2501089C
- Authority
- CA
- Canada
- Prior art keywords
- cancer
- compound
- kahalalide
- val
- allo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBPCT/GB02/004735 | 2002-10-18 | ||
PCT/GB2002/004735 WO2003033012A1 (en) | 2001-10-19 | 2002-10-18 | Kahalalide compounds for use in cancer therapy |
GB0304367.6 | 2003-02-26 | ||
GBGB0304367.6A GB0304367D0 (en) | 2003-02-26 | 2003-02-26 | Methods for treating psoriasis |
GB0314725.3 | 2003-06-24 | ||
GB0314725A GB0314725D0 (en) | 2003-06-24 | 2003-06-24 | New antitumoral compounds |
PCT/US2003/033207 WO2004035613A2 (en) | 2002-10-18 | 2003-10-20 | 4-methylhexanoic kahalaide f compound |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2501089A1 CA2501089A1 (en) | 2004-04-29 |
CA2501089C true CA2501089C (en) | 2012-07-17 |
Family
ID=32110555
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2501089A Expired - Fee Related CA2501089C (en) | 2002-10-18 | 2003-10-20 | 4-methylhexanoic kahalaide f compound |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP1572726B1 (zh) |
JP (1) | JP4430009B2 (zh) |
CN (2) | CN100591691C (zh) |
BR (1) | BR0315489A (zh) |
CA (1) | CA2501089C (zh) |
ES (1) | ES2357644T3 (zh) |
MX (1) | MXPA05004133A (zh) |
NZ (1) | NZ539093A (zh) |
WO (1) | WO2004035613A2 (zh) |
ZA (1) | ZA200502926B (zh) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6274551B1 (en) * | 1994-02-03 | 2001-08-14 | Pharmamar, S.A. | Cytotoxic and antiviral compound |
GB0304367D0 (en) | 2003-02-26 | 2003-04-02 | Pharma Mar Sau | Methods for treating psoriasis |
US7507708B2 (en) | 2003-02-26 | 2009-03-24 | Pharma Mar, S.A.U. | Antitumoral compounds |
GB0321066D0 (en) | 2003-09-09 | 2003-10-08 | Pharma Mar Sau | New antitumoral compounds |
JP2011500723A (ja) * | 2007-10-19 | 2011-01-06 | ファルマ・マール・ソシエダード・アノニマ | 改善された抗腫瘍治療 |
DE102008005097B4 (de) * | 2008-01-18 | 2011-04-07 | Leibnitz-Institut für Meereswissenschaften | Antitumoraler Cyclodepsipeptide, deren Herstellung und Verwendung |
CN101965192A (zh) * | 2008-03-07 | 2011-02-02 | 法马马有限公司 | 改善的抗肿瘤治疗 |
WO2009135939A2 (en) * | 2008-05-09 | 2009-11-12 | Pharma Mar, S.A. | Depsipeptide for use in cancer therapy |
LT2786756T (lt) | 2010-11-12 | 2020-05-11 | Pharma Mar, S.A. | Derinių terapija su topoizomerazės inhibitoriumi |
JOP20190254A1 (ar) | 2017-04-27 | 2019-10-27 | Pharma Mar Sa | مركبات مضادة للأورام |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6274551B1 (en) * | 1994-02-03 | 2001-08-14 | Pharmamar, S.A. | Cytotoxic and antiviral compound |
GB9302046D0 (en) * | 1993-02-03 | 1993-03-24 | Pharma Mar Sa | Antiumoral compound-v |
NZ525243A (en) * | 2000-10-31 | 2005-01-28 | Pharma Mar S | A lyophilised formulation comprising kahalalide F, a peptide isolated from a herbivorous marine species of mollusc, Elysia rufescens, to treat cancer |
CA2462639A1 (en) * | 2001-10-19 | 2003-04-24 | Pharma Mar, S.A. | Kahalalide compounds for use in cancer therapy |
-
2003
- 2003-10-20 EP EP03779140A patent/EP1572726B1/en not_active Expired - Lifetime
- 2003-10-20 JP JP2005501483A patent/JP4430009B2/ja not_active Expired - Fee Related
- 2003-10-20 CA CA2501089A patent/CA2501089C/en not_active Expired - Fee Related
- 2003-10-20 CN CN200380101647A patent/CN100591691C/zh not_active Expired - Fee Related
- 2003-10-20 WO PCT/US2003/033207 patent/WO2004035613A2/en active Application Filing
- 2003-10-20 MX MXPA05004133A patent/MXPA05004133A/es active IP Right Grant
- 2003-10-20 BR BR0315489-0A patent/BR0315489A/pt not_active IP Right Cessation
- 2003-10-20 NZ NZ539093A patent/NZ539093A/en not_active IP Right Cessation
- 2003-10-20 ES ES03779140T patent/ES2357644T3/es not_active Expired - Lifetime
- 2003-10-20 CN CNA2007101122538A patent/CN101077885A/zh active Pending
-
2005
- 2005-04-11 ZA ZA200502926A patent/ZA200502926B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
MXPA05004133A (es) | 2005-10-05 |
ES2357644T3 (es) | 2011-04-28 |
JP4430009B2 (ja) | 2010-03-10 |
BR0315489A (pt) | 2005-08-23 |
CN101077885A (zh) | 2007-11-28 |
JP2006517195A (ja) | 2006-07-20 |
CN100591691C (zh) | 2010-02-24 |
CN1705677A (zh) | 2005-12-07 |
EP1572726A2 (en) | 2005-09-14 |
WO2004035613A3 (en) | 2004-07-29 |
WO2004035613A2 (en) | 2004-04-29 |
NZ539093A (en) | 2007-10-26 |
ZA200502926B (en) | 2006-02-22 |
CA2501089A1 (en) | 2004-04-29 |
EP1572726B1 (en) | 2010-12-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US7683028B2 (en) | Kahalalide compositions | |
JP5372096B2 (ja) | 新規な抗腫瘍化合物 | |
CA2501089C (en) | 4-methylhexanoic kahalaide f compound | |
RU2356908C2 (ru) | Новые противоопухолевые соединения | |
AU2003285911B2 (en) | 4-methylhexanoic kahalaide F compound |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |
Effective date: 20171020 |