CA2493085C - Dispensing apparatus - Google Patents
Dispensing apparatus Download PDFInfo
- Publication number
- CA2493085C CA2493085C CA2493085A CA2493085A CA2493085C CA 2493085 C CA2493085 C CA 2493085C CA 2493085 A CA2493085 A CA 2493085A CA 2493085 A CA2493085 A CA 2493085A CA 2493085 C CA2493085 C CA 2493085C
- Authority
- CA
- Canada
- Prior art keywords
- pin
- pin engagement
- pin support
- engagement member
- support frame
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000008878 coupling Effects 0.000 claims description 17
- 238000010168 coupling process Methods 0.000 claims description 17
- 238000005859 coupling reaction Methods 0.000 claims description 17
- 230000013011 mating Effects 0.000 claims description 15
- 230000000295 complement effect Effects 0.000 claims description 9
- 210000005069 ears Anatomy 0.000 claims description 5
- 239000012530 fluid Substances 0.000 abstract description 30
- 238000013459 approach Methods 0.000 description 4
- 238000012360 testing method Methods 0.000 description 3
- 239000000463 material Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000009471 action Effects 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000003252 repetitive effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1065—Multiple transfer devices
- G01N35/1074—Multiple transfer devices arranged in a two-dimensional array
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0241—Drop counters; Drop formers
- B01L3/0244—Drop counters; Drop formers using pins
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/54—Supports specially adapted for pipettes and burettes
- B01L9/547—Supports specially adapted for pipettes and burettes for dispensing pins
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00351—Means for dispensing and evacuation of reagents
- B01J2219/00387—Applications using probes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/00527—Sheets
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/04—Exchange or ejection of cartridges, containers or reservoirs
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/02—Drop detachment mechanisms of single droplets from nozzles or pins
- B01L2400/022—Drop detachment mechanisms of single droplets from nozzles or pins droplet contacts the surface of the receptacle
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/54—Supports specially adapted for pipettes and burettes
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
- C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00178—Special arrangements of analysers
- G01N2035/00237—Handling microquantities of analyte, e.g. microvalves, capillary networks
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N2035/1027—General features of the devices
- G01N2035/1034—Transferring microquantities of liquid
- G01N2035/1037—Using surface tension, e.g. pins or wires
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Devices For Use In Laboratory Experiments (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/214,943 US6997066B2 (en) | 2002-08-07 | 2002-08-07 | Dispensing apparatus |
| US10/214,943 | 2002-08-07 | ||
| PCT/US2003/023954 WO2004014555A1 (en) | 2002-08-07 | 2003-07-31 | Dispensing apparatus |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2493085A1 CA2493085A1 (en) | 2004-02-19 |
| CA2493085C true CA2493085C (en) | 2011-09-20 |
Family
ID=31494747
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2493085A Expired - Lifetime CA2493085C (en) | 2002-08-07 | 2003-07-31 | Dispensing apparatus |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US6997066B2 (enExample) |
| EP (1) | EP1526919B1 (enExample) |
| JP (2) | JP4905910B2 (enExample) |
| AU (2) | AU2003257080B2 (enExample) |
| CA (1) | CA2493085C (enExample) |
| WO (1) | WO2004014555A1 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7267801B2 (en) * | 1999-06-03 | 2007-09-11 | Beckman Coulter, Inc. | Pipette tip box shucking method and apparatus |
| CN1385518A (zh) * | 2001-04-23 | 2002-12-18 | 株式会社百尼尔 | 生物学试料的微细排列用点样装置及该装置中使用的点样针 |
| WO2002089263A1 (en) * | 2001-04-23 | 2002-11-07 | Transition Automation, Inc. | Fine resolution pin support fixture with light weight design |
| DE10135963B4 (de) * | 2001-07-24 | 2005-09-29 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Vorrichtung zum Pipettieren einer Flüssigkeit |
| US7267568B2 (en) * | 2004-04-21 | 2007-09-11 | Bigband Networks Bas, Inc. | Floating connectors |
| DE202004007120U1 (de) * | 2004-05-03 | 2005-09-29 | Zeitz, Patric, Dr. | Druckkopfsystem für Microarray Drucker |
| US7219567B2 (en) * | 2005-01-05 | 2007-05-22 | Bio-Magnetics Ltd. | Combinatorial pipettor device |
| US8150548B2 (en) * | 2005-11-07 | 2012-04-03 | Sasan Raghibizadeh | Apparatus for process automation using pin array and actuators |
| TWI415770B (zh) * | 2006-01-13 | 2013-11-21 | Universal Bio Research Co Ltd | 變形式分注管、變形式分注裝置及變形式分注處理方法 |
| FR2920675B1 (fr) * | 2007-09-10 | 2010-12-03 | Gilson Sas | Systeme de pipetage multicanaux comprenant un porte-pistons a guidage ameliore |
| GB2467929A (en) * | 2009-02-19 | 2010-08-25 | Nordiag Asa | Pipette with bellows |
| USD677400S1 (en) * | 2010-02-26 | 2013-03-05 | Roche Diagnostics Operations, Inc. | Pipette tip plate |
| FR2956821B1 (fr) * | 2010-02-26 | 2012-04-27 | Millipore Corp | Dispositif pour separer une membrane d'un support |
| JP2018079938A (ja) * | 2016-11-14 | 2018-05-24 | ムロオカ産業株式会社 | ピペット保管装置 |
| JP7343124B2 (ja) | 2018-03-02 | 2023-09-12 | プソマーゲン， インコーポレイテッド | 磁場及びデバイスを使用したハイスループットな粒子ハンドリングのための方法及びシステム |
| CN112888950B (zh) | 2018-08-08 | 2024-05-28 | 安德鲁联合有限公司 | 用于改善液体处理的系统和方法 |
| US12440910B2 (en) | 2019-07-18 | 2025-10-14 | Transition Automation, Inc. | Paste retainer systems and methods for use in paste printing systems |
| US12162096B1 (en) | 2019-09-10 | 2024-12-10 | Transition Automation, Inc. | Squeegee blade holder with secondary blade mounting apparatus |
| USD963820S1 (en) | 2020-09-29 | 2022-09-13 | Tabitha Angel Bryant | Sanitizing fogger |
| CN112169857B (zh) * | 2020-10-19 | 2021-10-26 | 西南医科大学 | 一种移液枪枪头快速整理收纳盒以及使用方法 |
| CN113368918B (zh) * | 2021-06-21 | 2022-04-26 | 合肥瀚海星点生物科技有限公司 | 一种基于微流控打印的多通道分液装置与分液方法 |
| WO2023126874A1 (en) * | 2021-12-29 | 2023-07-06 | Andrew Alliance S.A. | Sample extraction system and method |
| US12226062B1 (en) | 2023-01-11 | 2025-02-18 | Transition Automation, Inc. | Squeegee holder with an integrated clamp bar |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5525302A (en) | 1991-02-01 | 1996-06-11 | Astle; Thomas W. | Method and device for simultaneously transferring plural samples |
| US5497670A (en) | 1995-03-31 | 1996-03-12 | Carl; Richard A. | Liquid dispensing apparatus including means for loading pipette tips onto liquid dispensing cylinders and maintaining the loading force during the apparatus operation cycle |
| US6024925A (en) | 1997-01-23 | 2000-02-15 | Sequenom, Inc. | Systems and methods for preparing low volume analyte array elements |
| US6116099A (en) | 1996-11-18 | 2000-09-12 | Carl; Richard A. | Liquid dispensing apparatus having means for loading pipette tips onto fluid dispensing cylinders |
| US6101946A (en) | 1997-11-21 | 2000-08-15 | Telechem International Inc. | Microarray printing device including printing pins with flat tips and exterior channel and method of manufacture |
| US6269846B1 (en) * | 1998-01-13 | 2001-08-07 | Genetic Microsystems, Inc. | Depositing fluid specimens on substrates, resulting ordered arrays, techniques for deposition of arrays |
| US6415669B1 (en) * | 1998-04-09 | 2002-07-09 | Ccs Packard, Inc. | Dispensing apparatus having means for loading pipette tips in a dispense head |
| US6551557B1 (en) * | 1998-07-07 | 2003-04-22 | Cartesian Technologies, Inc. | Tip design and random access array for microfluidic transfer |
| US6423536B1 (en) * | 1999-08-02 | 2002-07-23 | Molecular Dynamics, Inc. | Low volume chemical and biochemical reaction system |
| US6447723B1 (en) * | 2000-03-13 | 2002-09-10 | Packard Instrument Company, Inc. | Microarray spotting instruments incorporating sensors and methods of using sensors for improving performance of microarray spotting instruments |
| US6610253B2 (en) | 2000-05-31 | 2003-08-26 | Autosplice, Inc. | Liquid pin transfer assembly with common pin bias |
| JP3677207B2 (ja) * | 2000-12-08 | 2005-07-27 | 日立ソフトウエアエンジニアリング株式会社 | スポットピン及びバイオチップ作製装置 |
| US6827905B2 (en) * | 2002-01-14 | 2004-12-07 | Becton, Dickinson And Company | Pin tool apparatus and method |
-
2002
- 2002-08-07 US US10/214,943 patent/US6997066B2/en not_active Expired - Lifetime
-
2003
- 2003-07-31 EP EP03784859.5A patent/EP1526919B1/en not_active Expired - Lifetime
- 2003-07-31 JP JP2004527691A patent/JP4905910B2/ja not_active Expired - Lifetime
- 2003-07-31 CA CA2493085A patent/CA2493085C/en not_active Expired - Lifetime
- 2003-07-31 WO PCT/US2003/023954 patent/WO2004014555A1/en not_active Ceased
- 2003-07-31 AU AU2003257080A patent/AU2003257080B2/en not_active Expired
-
2005
- 2005-06-30 US US11/171,687 patent/US7387037B2/en not_active Expired - Lifetime
-
2009
- 2009-03-11 AU AU2009200967A patent/AU2009200967B2/en not_active Expired
-
2011
- 2011-02-28 JP JP2011042037A patent/JP5201750B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US6997066B2 (en) | 2006-02-14 |
| AU2003257080B2 (en) | 2008-12-11 |
| AU2009200967B2 (en) | 2010-06-24 |
| US7387037B2 (en) | 2008-06-17 |
| US20050245113A1 (en) | 2005-11-03 |
| CA2493085A1 (en) | 2004-02-19 |
| JP2005534493A (ja) | 2005-11-17 |
| EP1526919A1 (en) | 2005-05-04 |
| AU2003257080A1 (en) | 2004-02-25 |
| EP1526919B1 (en) | 2013-04-24 |
| US20040026444A1 (en) | 2004-02-12 |
| WO2004014555A1 (en) | 2004-02-19 |
| AU2009200967A1 (en) | 2009-04-02 |
| JP2011149948A (ja) | 2011-08-04 |
| JP4905910B2 (ja) | 2012-03-28 |
| JP5201750B2 (ja) | 2013-06-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKEX | Expiry |
Effective date: 20230731 |