CA2483875A1 - Derives de l'erythromycine 6,11 bicyclique - Google Patents

Derives de l'erythromycine 6,11 bicyclique Download PDF

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Publication number
CA2483875A1
CA2483875A1 CA002483875A CA2483875A CA2483875A1 CA 2483875 A1 CA2483875 A1 CA 2483875A1 CA 002483875 A CA002483875 A CA 002483875A CA 2483875 A CA2483875 A CA 2483875A CA 2483875 A1 CA2483875 A1 CA 2483875A1
Authority
CA
Canada
Prior art keywords
present
compounds
subject
erythromycin derivatives
invention further
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002483875A
Other languages
English (en)
Other versions
CA2483875C (fr
Inventor
Yat Sun Or
Guoqiang Wang
Ly Tam Phan
Deqiang Niu
Yao-Ling Qiu
Nha Huu Vo
Jay Judson Farmer
Ying Hou
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Enanta Pharmaceuticals Inc
Original Assignee
Enanta Pharmaceuticals, Inc.
Yat Sun Or
Guoqiang Wang
Ly Tam Phan
Deqiang Niu
Yao-Ling Qiu
Nha Huu Vo
Jay Judson Farmer
Ying Hou
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Enanta Pharmaceuticals, Inc., Yat Sun Or, Guoqiang Wang, Ly Tam Phan, Deqiang Niu, Yao-Ling Qiu, Nha Huu Vo, Jay Judson Farmer, Ying Hou filed Critical Enanta Pharmaceuticals, Inc.
Priority claimed from US10/436,622 external-priority patent/US7129221B2/en
Publication of CA2483875A1 publication Critical patent/CA2483875A1/fr
Application granted granted Critical
Publication of CA2483875C publication Critical patent/CA2483875C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
CA002483875A 2002-05-13 2003-05-13 Derives de l'erythromycine 6,11 bicyclique Expired - Fee Related CA2483875C (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US14439602A 2002-05-13 2002-05-13
US10/144,396 2002-05-13
PCT/US2003/014914 WO2003095466A1 (fr) 2002-05-13 2003-05-13 Derives de l'erythromycine 6,11 bicyclique
US10/436,622 2003-05-13
US10/436,622 US7129221B2 (en) 2002-05-13 2003-05-13 6,11-bicyclic erythromycin derivatives

Publications (2)

Publication Number Publication Date
CA2483875A1 true CA2483875A1 (fr) 2003-11-20
CA2483875C CA2483875C (fr) 2008-09-23

Family

ID=29418515

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002483875A Expired - Fee Related CA2483875C (fr) 2002-05-13 2003-05-13 Derives de l'erythromycine 6,11 bicyclique

Country Status (3)

Country Link
AU (1) AU2003229037B8 (fr)
CA (1) CA2483875C (fr)
WO (1) WO2003095466A1 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005070918A1 (fr) * 2002-05-13 2005-08-04 Enanta Pharmaceuticals, Inc. Procede de preparation de derives bicycliques 6-11 d'erythromycine
US7910558B2 (en) 2002-05-13 2011-03-22 Enanta Pharmaceuticals, Inc. Bridged macrocyclic compounds and processes for the preparation thereof
US7135573B2 (en) 2002-05-13 2006-11-14 Enanta Pharmaceuticals, Inc. Processes for the preparation of O-(6-Pyrazol-1-yl-pyridin-3-ylmethyl)-hydroxylamine
US20050101548A1 (en) * 2003-09-12 2005-05-12 Xiaodong Lin Antimicrobial derivatives
WO2005067564A2 (fr) 2004-01-07 2005-07-28 Enanta Pharmaceuticals, Inc. Derives d'erythromycine 6-11 bicyclique
CN1910171B (zh) * 2004-01-14 2011-09-28 伊南塔医药品股份有限公司 6-11双环红霉素衍生物的制备方法
WO2005080408A1 (fr) * 2004-01-23 2005-09-01 Enanta Pharmaceuticals, Inc. Composes macrocycliques pontes et procedes de preparation desdits composes
US7384921B2 (en) 2004-02-20 2008-06-10 Enanta Pharmaceuticals, Inc. Polymorphic forms of 6-11 bicyclic ketolide derivatives
JP2008522978A (ja) 2004-12-07 2008-07-03 エナンタ ファーマシューティカルズ インコーポレイテッド ３，６−ビシクロライド
US7229972B2 (en) 2004-12-07 2007-06-12 Enanta Pharmaceuticals, Inc. 3,6-Bicyclolides
US7312201B2 (en) 2004-12-13 2007-12-25 Enanta Pharmaceuticals, Inc. Tetracyclic bicyclolides
WO2006065721A2 (fr) 2004-12-13 2006-06-22 Enanta Pharmaceuticals, Inc. Bicyclolides de 11, 12-lactone
US7384922B2 (en) 2005-05-04 2008-06-10 Enanta Pharmaceuticals, Inc. 6-11 bridged oxime erythromycin derivatives
MX2007013730A (es) * 2005-05-04 2008-01-28 Enanta Pharm Inc Derivados de eritromicina oxima con puente 6-11.
US7589067B2 (en) 2005-10-12 2009-09-15 Enanta Pharmaceuticals, Inc. 6, 11-bridged tricyclic macrolides
US7407942B2 (en) 2006-03-29 2008-08-05 Emata Pharmaceuticals, Inc 3,6-bridged 9,12-oxolides

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR015986A1 (es) * 1997-10-29 2001-05-30 Abbott Lab Derivados de eritromicina puenteados en 6,11, composiciones farmaceuticas que los contienen, su uso para la manufactura de un medicamento y procedimientospara su preparacion
US6046171A (en) * 1997-10-29 2000-04-04 Abbott Laboratories 6,11-bridged erythromycin derivatives

Also Published As

Publication number Publication date
AU2003229037A1 (en) 2003-11-11
CA2483875C (fr) 2008-09-23
AU2003229037B2 (en) 2007-01-18
WO2003095466A1 (fr) 2003-11-20
AU2003229037B8 (en) 2009-07-02

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Effective date: 20190513