CA2476427A1 - Partial peptide mimetics and methods - Google Patents
Partial peptide mimetics and methods Download PDFInfo
- Publication number
- CA2476427A1 CA2476427A1 CA002476427A CA2476427A CA2476427A1 CA 2476427 A1 CA2476427 A1 CA 2476427A1 CA 002476427 A CA002476427 A CA 002476427A CA 2476427 A CA2476427 A CA 2476427A CA 2476427 A1 CA2476427 A1 CA 2476427A1
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- Prior art keywords
- seq
- partial peptide
- cells
- peptide mimetic
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4747—Apoptosis related proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
- C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- Ophthalmology & Optometry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Reproductive Health (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35927202P | 2002-02-20 | 2002-02-20 | |
| US60/359,272 | 2002-02-20 | ||
| PCT/US2003/005106 WO2003070751A2 (en) | 2002-02-20 | 2003-02-20 | Partial peptide mimetics and methods |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2476427A1 true CA2476427A1 (en) | 2003-08-28 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002476427A Abandoned CA2476427A1 (en) | 2002-02-20 | 2003-02-20 | Partial peptide mimetics and methods |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US7056514B2 (enExample) |
| EP (1) | EP1572719A4 (enExample) |
| JP (1) | JP2005536453A (enExample) |
| AU (1) | AU2003211163A1 (enExample) |
| CA (1) | CA2476427A1 (enExample) |
| WO (1) | WO2003070751A2 (enExample) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6486125B1 (en) * | 1996-05-24 | 2002-11-26 | Regents Of The University Of Minnesota | Synthesis of soluble β-sheet forming peptides |
| WO2003070751A2 (en) * | 2002-02-20 | 2003-08-28 | Regents Of The University Of Minnesota | Partial peptide mimetics and methods |
| CN1688696A (zh) * | 2002-09-18 | 2005-10-26 | 蒙特利尔大学医疗中心 | Ghrh类似物 |
| JP2007512234A (ja) * | 2003-10-17 | 2007-05-17 | リージェンツ オブ ザ ユニバーシティ オブ ミネソタ | 治療活性を有する修飾ポリペプチド及びその使用方法 |
| US7493333B2 (en) | 2004-09-03 | 2009-02-17 | Biowisdom Limited | System and method for parsing and/or exporting data from one or more multi-relational ontologies |
| US7496593B2 (en) | 2004-09-03 | 2009-02-24 | Biowisdom Limited | Creating a multi-relational ontology having a predetermined structure |
| US7505989B2 (en) | 2004-09-03 | 2009-03-17 | Biowisdom Limited | System and method for creating customized ontologies |
| US20060053172A1 (en) * | 2004-09-03 | 2006-03-09 | Biowisdom Limited | System and method for creating, editing, and using multi-relational ontologies |
| CA2867023A1 (en) | 2004-10-04 | 2006-04-20 | Kevin H. Mayo | Calixarene-based peptide conformation mimetics, methods of use, and methods of making |
| JP2010519338A (ja) * | 2007-03-01 | 2010-06-03 | マリンクロット インコーポレイテッド | 組込み型光活性ペプチドおよびその使用 |
| EP2131861A2 (en) * | 2007-03-01 | 2009-12-16 | Mallinckrodt Inc. | Integrated photoactive small molecules and uses thereof |
| EP2178849A1 (en) * | 2007-07-31 | 2010-04-28 | Mallinckrodt Inc. | Integrated photoactive agents and uses thereof |
| US20210138080A1 (en) | 2018-06-29 | 2021-05-13 | Glykos Biomedical Oy | Conjugates |
| US20230038373A1 (en) | 2019-12-18 | 2023-02-09 | Glykos Biomedical Oy | Stabile conjugate |
Family Cites Families (37)
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| EP0652230B1 (en) | 1987-08-11 | 2005-12-14 | New York University | Biologically active bactericidal/permeability-increasing protein fragments |
| US5198541A (en) | 1987-08-11 | 1993-03-30 | New York University | Dna encoding bactericidal/permeability-increasing proteins |
| US5171739A (en) | 1989-02-14 | 1992-12-15 | Incyte Pharmaceuticals, Inc. | Treatment of endotoxin-associated shock and preventation thereof using a BPI protein |
| US5234912A (en) | 1989-02-14 | 1993-08-10 | Incyte Pharmaceuticals, Inc. | Pharmaceutical compositions comprising recombinant BPI proteins and a lipid carrier and uses thereof |
| WO1994025476A1 (en) | 1993-04-30 | 1994-11-10 | Incyte Pharmaceuticals, Inc. | Recombinant bpi-based and lbp-based proteins, nucleic acid molecules encoding same, methods of producing same, and uses thereof |
| US5334584A (en) | 1989-02-14 | 1994-08-02 | Incyte Pharamaceuticals, Inc. | Recombinant, non-glycosylated bpi protein and uses thereof |
| US5089274A (en) | 1989-02-14 | 1992-02-18 | Incyte Pharmaceuticals, Inc. | Use of bactericidal/permeability increasing protein or biologically active analogs thereof to treat endotoxin-related disorders |
| US5496938A (en) | 1990-06-11 | 1996-03-05 | Nexstar Pharmaceuticals, Inc. | Nucleic acid ligands to HIV-RT and HIV-1 rev |
| US5595887A (en) | 1990-07-16 | 1997-01-21 | Bionebraska, Inc. | Purification directed cloning of peptides using carbonic anhydrase as the affinity binding segment |
| CA2095861C (en) | 1990-11-28 | 2002-06-11 | Ronald H. Hoess | Structural proteins from artificial genes |
| AU9127591A (en) | 1990-12-03 | 1992-06-25 | New York University | Biologically active bactericidal/permeability-increasing protein fragments |
| US5190873A (en) | 1991-06-21 | 1993-03-02 | California Institute Of Biological Research | Hybrid tryptophan aporepressor containing ligand binding sites |
| WO1993023434A2 (en) | 1992-05-19 | 1993-11-25 | Xoma Corporation | Bpi-immunoglobulin fusion proteins |
| EP0675127A1 (en) | 1992-12-28 | 1995-10-04 | Nippon Shinyaku Company, Limited | Quinolinecarboxylic acid derivative and process for producing the same |
| WO1994017819A1 (en) | 1993-02-02 | 1994-08-18 | Xoma Corporation | Pharmaceutical compositions containing bactericidal permeability increasing protein and a surfactant |
| US5420019A (en) | 1993-02-02 | 1995-05-30 | Xoma Corporation | Stable bactericidal/permeability-increasing protein muteins |
| US5348942A (en) | 1993-03-12 | 1994-09-20 | Xoma Corporation | Therapeutic uses of bactericidal/permeability increasing protein products |
| AU694108B2 (en) | 1993-03-12 | 1998-07-16 | Xoma Corporation | Biologically active peptides from functional domains of bactericidal/permeability-increasing protein and uses thereof |
| AU7175694A (en) | 1993-06-17 | 1995-01-17 | Xoma Corporation | Lipopolysaccharide binding protein derivatives |
| DE69431922T2 (de) | 1993-07-02 | 2003-11-13 | Incyte Pharmaceuticals, Inc. | Glycosilierte und nichtglycolisierte bakterizide/die permeabilität erhoehende proteine und methoden zu ihrer herstellung |
| WO1995002414A1 (en) | 1993-07-14 | 1995-01-26 | Xoma Corporation | Method for potentiating bpi protein product bactericidal activity by administration of lbp protein products |
| US5447913A (en) | 1994-03-11 | 1995-09-05 | Xoma Corporation | Therapeutic uses of bactericidal/permeability-increasing protein dimer products |
| US5786324A (en) | 1994-03-24 | 1998-07-28 | Regents Of The University Of Minnesota | Synthetic peptides with bactericidal activity and endotoxin neutralizing activity for gram negative bacteria and methods for their use |
| US5830860A (en) | 1994-03-24 | 1998-11-03 | Regents Of The University Of Minnesota | Peptides with bactericidal activity and endotoxin neutralizing activity for gram negative bacteria and methods for their use |
| US5639725A (en) | 1994-04-26 | 1997-06-17 | Children's Hospital Medical Center Corp. | Angiostatin protein |
| US5837682A (en) | 1996-03-08 | 1998-11-17 | The Children's Medical Center Corporation | Angiostatin fragments and method of use |
| GB9506806D0 (en) | 1995-04-01 | 1995-05-24 | Univ Leeds | Improvements relating to polymers |
| WO1996037212A1 (en) | 1995-05-26 | 1996-11-28 | Torrey Pines Institute For Molecular Studies | POLYPEPTIDE COMPOUNDS THAT FORM β SHEETS |
| US5854205A (en) | 1995-10-23 | 1998-12-29 | The Children's Medical Center Corporation | Therapeutic antiangiogenic compositions and methods |
| US6486125B1 (en) * | 1996-05-24 | 2002-11-26 | Regents Of The University Of Minnesota | Synthesis of soluble β-sheet forming peptides |
| US5955577A (en) * | 1996-06-27 | 1999-09-21 | Regents Of The University Of Minnesota | Method for synthesizing a water-soluble β-sheet forming peptide |
| AU2001231016A1 (en) | 2000-01-20 | 2001-07-31 | Regents Of The University Of Minnesota | Peptides with antibacterial activity |
| WO2003070751A2 (en) | 2002-02-20 | 2003-08-28 | Regents Of The University Of Minnesota | Partial peptide mimetics and methods |
| JP2007512234A (ja) | 2003-10-17 | 2007-05-17 | リージェンツ オブ ザ ユニバーシティ オブ ミネソタ | 治療活性を有する修飾ポリペプチド及びその使用方法 |
| ITPD20040171A1 (it) | 2004-06-29 | 2004-09-29 | Maus Spa | Dispositivo per il bloccaggio di pezzi soggetti a lavorazioni meccaniche e macchina utensile includente detto dispositivo |
| CA2867023A1 (en) | 2004-10-04 | 2006-04-20 | Kevin H. Mayo | Calixarene-based peptide conformation mimetics, methods of use, and methods of making |
| US20070010438A1 (en) * | 2005-07-08 | 2007-01-11 | Mayo Kevin H | Tumor treatment using beta-sheet peptides and radiotherapy |
-
2003
- 2003-02-20 WO PCT/US2003/005106 patent/WO2003070751A2/en not_active Ceased
- 2003-02-20 EP EP03742842A patent/EP1572719A4/en not_active Withdrawn
- 2003-02-20 CA CA002476427A patent/CA2476427A1/en not_active Abandoned
- 2003-02-20 AU AU2003211163A patent/AU2003211163A1/en not_active Abandoned
- 2003-02-20 JP JP2003569658A patent/JP2005536453A/ja active Pending
- 2003-02-20 US US10/371,406 patent/US7056514B2/en not_active Expired - Lifetime
-
2006
- 2006-02-02 US US11/346,504 patent/US7339023B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1572719A4 (en) | 2007-11-14 |
| US20060128629A1 (en) | 2006-06-15 |
| US20040053828A1 (en) | 2004-03-18 |
| EP1572719A2 (en) | 2005-09-14 |
| WO2003070751A3 (en) | 2007-04-05 |
| WO2003070751A2 (en) | 2003-08-28 |
| US7056514B2 (en) | 2006-06-06 |
| US7339023B2 (en) | 2008-03-04 |
| AU2003211163A1 (en) | 2003-09-09 |
| JP2005536453A (ja) | 2005-12-02 |
| AU2003211163A8 (en) | 2003-09-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |