CA2476275A1 - Schwann cell bridge implants and phosphodiesterase inhibitors to stimulate cns nerve regeneration - Google Patents
Schwann cell bridge implants and phosphodiesterase inhibitors to stimulate cns nerve regeneration Download PDFInfo
- Publication number
- CA2476275A1 CA2476275A1 CA002476275A CA2476275A CA2476275A1 CA 2476275 A1 CA2476275 A1 CA 2476275A1 CA 002476275 A CA002476275 A CA 002476275A CA 2476275 A CA2476275 A CA 2476275A CA 2476275 A1 CA2476275 A1 CA 2476275A1
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- cells
- camp
- injury
- cyclic nucleotide
- implanting
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Classifications
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- A—HUMAN NECESSITIES
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- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
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| US35430602P | 2002-02-07 | 2002-02-07 | |
| US60/354,306 | 2002-02-07 | ||
| PCT/US2003/003513 WO2003065994A2 (en) | 2002-02-07 | 2003-02-07 | Schwann cell and phosphodiesterase inhibitors based therapy |
Publications (1)
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| CA2476275A1 true CA2476275A1 (en) | 2003-08-14 |
Family
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Family Applications (1)
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| CA002476275A Abandoned CA2476275A1 (en) | 2002-02-07 | 2003-02-07 | Schwann cell bridge implants and phosphodiesterase inhibitors to stimulate cns nerve regeneration |
Country Status (7)
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| JP (1) | JP2005516988A (https=) |
| KR (1) | KR20040101220A (https=) |
| AU (1) | AU2003210869A1 (https=) |
| CA (1) | CA2476275A1 (https=) |
| WO (1) | WO2003065994A2 (https=) |
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| US8153646B2 (en) | 2000-08-10 | 2012-04-10 | Dart Neuroscience (Cayman) Ltd. | Phosphodiesterase 4 inhibitors for cognitive and motor rehabilitation |
| US9931318B2 (en) | 2003-04-08 | 2018-04-03 | Dart Neuroscience (Cayman) Ltd. | Phosphodiesterase 4 inhibitors for cognitive and motor rehabilitation |
| JP3886346B2 (ja) * | 2001-06-22 | 2007-02-28 | サンバイオ，インコーポレイティド | 骨髄間質細胞由来Ｓｃｈｗａｎｎ細胞を含む神経再生用医薬組成物 |
| GB0420722D0 (en) * | 2004-09-17 | 2004-10-20 | Addex Pharmaceuticals Sa | Novel allosteric modulators |
| US8309057B2 (en) * | 2005-06-10 | 2012-11-13 | The Invention Science Fund I, Llc | Methods for elevating neurotrophic agents |
| AR059898A1 (es) | 2006-03-15 | 2008-05-07 | Janssen Pharmaceutica Nv | Derivados de 3-ciano-piridona 1,4-disustituida y su uso como moduladores alostericos de los receptores mglur2 |
| ES2412481T3 (es) * | 2006-05-19 | 2013-07-11 | Dart Neuroscience Llc | Inhibidores de la fosfodiesterasa 4 para la rehabilitación motora |
| US7811549B2 (en) | 2006-07-05 | 2010-10-12 | Adenobio N.V. | Methods, compositions, unit dosage forms, and kits for pharmacologic stress testing with reduced side effects |
| KR20080007800A (ko) * | 2006-07-18 | 2008-01-23 | 한훈 | 씨디34 음성 및 씨디45 양성의 제대혈 유래 줄기세포를이용한 척수 손상 세포 치료제 조성물 |
| TW200845978A (en) | 2007-03-07 | 2008-12-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-tetrahydropyran-phenyl)-pyridin-2-one derivatives |
| TW200900065A (en) | 2007-03-07 | 2009-01-01 | Janssen Pharmaceutica Nv | 3-cyano-4-(4-pyridinyloxy-phenyl)-pyridin-2-one derivatives |
| PL2200985T3 (pl) | 2007-09-14 | 2011-12-30 | Ortho Mcneil Janssen Pharmaceuticals Inc | 1,3-Dipodstawione-4-(arylo-X-fenylo)-1H-pirydyn-2-ony |
| SI2203439T1 (sl) | 2007-09-14 | 2011-05-31 | Ortho Mcneil Janssen Pharm | 1',3'-disubstituirani 4-fenil-3,4,5,6-tetrahidro-2H-1'H-(1,4')bipiridinil-2'-oni |
| WO2009092516A2 (en) * | 2008-01-22 | 2009-07-30 | Adenobio N.V. | Methods, compositions, unit dosage forms, and kits for pharmacologic stress testing with reduced side effects |
| WO2009111649A2 (en) * | 2008-03-05 | 2009-09-11 | Regenerative Research Foundation | Methods and compositions for delivery of exogenous factors to nervous system sites |
| EP2344470B1 (en) | 2008-09-02 | 2013-11-06 | Janssen Pharmaceuticals, Inc. | 3-azabicyclo[3.1.0]hexyl derivatives as modulators of metabotropic glutamate receptors |
| JP5690277B2 (ja) | 2008-11-28 | 2015-03-25 | ジャンセン ファーマシューティカルズ， インコーポレイテッド． | 代謝型グルタミン酸受容体の調節因子としてのインドールおよびベンゾオキサジン誘導体 |
| CN102439008B (zh) | 2009-05-12 | 2015-04-29 | 杨森制药有限公司 | 1,2,4-三唑并[4,3-a]吡啶衍生物及其用于治疗或预防神经和精神病症的用途 |
| BRPI1010831A2 (pt) | 2009-05-12 | 2016-04-05 | Addex Pharmaceuticals Sa | derivados de 1,2,4-triazolo[4,3-a]piridina e seu como moduladores alostéricos positivos de receptores de mglur2 |
| MY153913A (en) | 2009-05-12 | 2015-04-15 | Janssen Pharmaceuticals Inc | 7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors |
| CA2802896C (en) | 2010-07-01 | 2021-05-11 | Regenerative Research Foundation | Methods for culturing undifferentiated cells using sustained release compositions |
| ES2536433T3 (es) | 2010-11-08 | 2015-05-25 | Janssen Pharmaceuticals, Inc. | Derivados de 1,2,4-triazolo[4,3-a]piridina y su uso como moduladores alostéricos positivos de receptores mGluR2 |
| AU2011328203B2 (en) | 2010-11-08 | 2015-03-19 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors |
| US9271967B2 (en) | 2010-11-08 | 2016-03-01 | Janssen Pharmaceuticals, Inc. | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors |
| JO3368B1 (ar) | 2013-06-04 | 2019-03-13 | Janssen Pharmaceutica Nv | مركبات 6، 7- ثاني هيدرو بيرازولو [5،1-a] بيرازين- 4 (5 يد)- اون واستخدامها بصفة منظمات تفارغية سلبية لمستقبلات ميجلور 2 |
| JO3367B1 (ar) | 2013-09-06 | 2019-03-13 | Janssen Pharmaceutica Nv | مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2 |
| ME03518B (me) | 2014-01-21 | 2020-04-20 | Janssen Pharmaceutica Nv | Kombinacije koje obuhvataju pozitivne alosterične modulatore ili ortosterične agoniste metabotropnog glutamatergičnog receptora podtipa 2 i njihova primjena |
| MX386697B (es) | 2014-01-21 | 2025-03-19 | Janssen Pharmaceutica Nv | Combinaciones que comprenden agonistas ortostericos o moduladores alostericos positivos del receptor glutamatergico metabotropico de subtipo 2 y su uso |
| US11511136B2 (en) | 2017-11-17 | 2022-11-29 | The Research Foundation For The State University Of New York | Method for treating damaged peripheral nerves using x-ray microbeam irradiation |
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| US6104754A (en) * | 1995-03-15 | 2000-08-15 | Kabushiki Kaisha Toshiba | Moving picture coding and/or decoding systems, and variable-length coding and/or decoding system |
| US5714385A (en) * | 1995-05-10 | 1998-02-03 | Genentech, Inc. | Media for culturing schwann cells |
| US6002802A (en) * | 1995-10-27 | 1999-12-14 | Kabushiki Kaisha Toshiba | Video encoding and decoding apparatus |
| JP3681835B2 (ja) * | 1995-12-27 | 2005-08-10 | 三菱電機株式会社 | 画像符号化装置及び画像復号化装置及び符号化・復号化システム |
| US5827740A (en) * | 1996-07-30 | 1998-10-27 | Osiris Therapeutics, Inc. | Adipogenic differentiation of human mesenchymal stem cells |
| US6266370B1 (en) * | 1996-09-03 | 2001-07-24 | Nippon Telegraph And Telephone Corporation | Brightness-variation compensation method and coding/decoding apparatus for moving pictures |
| US5885834A (en) * | 1996-09-30 | 1999-03-23 | Epstein; Paul M. | Antisense oligodeoxynucleotide against phosphodiesterase |
| CA2320177A1 (en) * | 1998-02-13 | 1999-08-19 | Quvis, Inc. | Apparatus and method for optimized compression of interlaced motion images |
| US6268352B1 (en) * | 1998-09-02 | 2001-07-31 | The Regents Of The University Of California | Promoters of neural regeneration |
| US6459773B1 (en) * | 2000-05-05 | 2002-10-01 | Lucent Technologies Inc. | System to pre-qualify copper subscriber loops for high bandwidth access service using subscriber or network generated tones |
| EP1343528A2 (en) * | 2000-11-02 | 2003-09-17 | Research Foundation of City University of New York | Methods for stimulating nervous system regeneration and repair by inhibition phosphodiesterase type 4 |
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| EP1482916A2 (en) | 2004-12-08 |
| US20030220280A1 (en) | 2003-11-27 |
| KR20040101220A (ko) | 2004-12-02 |
| AU2003210869A1 (en) | 2003-09-02 |
| US20090136463A1 (en) | 2009-05-28 |
| JP2005516988A (ja) | 2005-06-09 |
| EP1482916A4 (en) | 2007-12-12 |
| WO2003065994A2 (en) | 2003-08-14 |
| WO2003065994A3 (en) | 2004-02-12 |
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