CA2472633C - S-dimethylarsino-thiosuccinic acid s-dimethylarsino-2-thiobenzoic acid s-(dimethylarsino) glutathione as treatments for cancer - Google Patents
S-dimethylarsino-thiosuccinic acid s-dimethylarsino-2-thiobenzoic acid s-(dimethylarsino) glutathione as treatments for cancer Download PDFInfo
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- CA2472633C CA2472633C CA2472633A CA2472633A CA2472633C CA 2472633 C CA2472633 C CA 2472633C CA 2472633 A CA2472633 A CA 2472633A CA 2472633 A CA2472633 A CA 2472633A CA 2472633 C CA2472633 C CA 2472633C
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- 230000002034 xenobiotic effect Effects 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/66—Arsenic compounds
- C07F9/70—Organo-arsenic compounds
- C07F9/72—Aliphatic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34649202P | 2002-01-07 | 2002-01-07 | |
| US60/346,492 | 2002-01-07 | ||
| PCT/US2003/000281 WO2003057012A2 (en) | 2002-01-07 | 2003-01-07 | S-dimethylarsino-thiosuccinic acid s-dimethylarsino-2-thiobenzoic acid s-(dimethylarsino) glutathione as treatments for cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2472633A1 CA2472633A1 (en) | 2003-07-17 |
| CA2472633C true CA2472633C (en) | 2014-07-08 |
Family
ID=23359639
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2472633A Expired - Fee Related CA2472633C (en) | 2002-01-07 | 2003-01-07 | S-dimethylarsino-thiosuccinic acid s-dimethylarsino-2-thiobenzoic acid s-(dimethylarsino) glutathione as treatments for cancer |
Country Status (6)
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4571408B2 (ja) * | 2002-01-07 | 2010-10-27 | ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム | 癌治療薬としての、ｓ−ジメチルアルシノ−チオコハク酸、ｓ−ジメチルアルシノ−２−チオ安息香酸、ｓ−（ジメチルアルシノ）グルタチオン |
| AU2011204901B2 (en) * | 2004-07-16 | 2013-09-12 | Board Of Regents, The University Of Texas System | Compounds and methods for treatment of cancer |
| TWI411431B (zh) * | 2004-07-16 | 2013-10-11 | Texas A & M Univ Sys | 有機砷化合物、其用於治療癌症之用途及包含其之醫藥組成物 |
| EP2394702B1 (en) * | 2005-07-29 | 2014-12-31 | Ziopharm Oncology, Inc. | Compounds and methods for the treatment of cancer |
| WO2007082104A2 (en) * | 2006-01-13 | 2007-07-19 | The Texas A & M University System | Compounds and methods for the treatment of cancer |
| TW200829261A (en) * | 2006-09-29 | 2008-07-16 | Ziopharm Oncology Inc | Method for controlling angiogenesis in animals |
| JP5301449B2 (ja) * | 2006-11-01 | 2013-09-25 | ニューサウス イノベイションズ ピーティーワイ リミテッド | 有機アルセノキシド化合物およびその使用 |
| KR20100100835A (ko) * | 2007-11-02 | 2010-09-15 | 지오팜 온콜로지 인코포레이티드 | 유기 비소제와의 병용 요법 |
| CN104592302A (zh) * | 2007-12-12 | 2015-05-06 | 日本苏爱康制药有限公司 | 用于治疗癌症的化合物和方法 |
| BRPI0912175A2 (pt) * | 2008-05-28 | 2015-10-06 | Basf Se | métodos para diagnosticar indução de enzima do fígado, para determinar se um composto é capaz de induzir indução de enzima do fígado em um indivíduo, e para identificar uma substância para tratar indução de enzima do fígado |
| EP2321012B1 (en) | 2008-08-20 | 2018-10-10 | Solasia Pharma K.K. | Organoarsenic compounds and methods for the treatment of cancer |
| CA2800260C (en) * | 2010-04-19 | 2013-07-09 | Sri International | Compositions and method for the treatment of multiple myeloma |
| CN105899486A (zh) * | 2013-12-05 | 2016-08-24 | 日本苏爱康制药有限公司 | 用于治疗癌症的化合物和方法 |
| CN112941027B (zh) * | 2021-03-19 | 2021-11-02 | 苏州大学 | 二甲基亚胂酸致人角质形成细胞恶性转化细胞株及其应用 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2349729A (en) * | 1940-08-24 | 1944-05-23 | Parke Davis & Co | Therapeutic arsenic preparation |
| US2701812A (en) * | 1951-06-26 | 1955-02-08 | Dainippon Pharmaceutical Co | Diarylarsenious acid derivatives and the preparation thereof |
| DE3229565A1 (de) * | 1982-08-07 | 1984-02-16 | Etschenberg, Eugen, Dr., 5000 Köln | Arsenhaltige nucleoside |
| FR2640269B1 (fr) * | 1988-12-13 | 1991-03-15 | Maes Ludo | Composes organometalliques, leurs modes de preparation et compositions pharmaceutiques les contenant |
| US6875451B2 (en) | 1997-10-15 | 2005-04-05 | Polarx Biopharmaceuticals Inc. | Compositions and methods for the treatment of primary and metastatic neoplastic diseases using arsenic compounds |
| PL343868A1 (en) | 1997-11-10 | 2001-09-10 | Sloan Kettering Inst Cancer | Process for producing arsenic trioxide formulations and methods for treating cancer using arsenic trioxide or melarsoprol |
| CN1233476A (zh) * | 1998-04-24 | 1999-11-03 | 陆道培 | 治疗急性白血病的药物及其制备方法 |
| EP1002537A1 (en) | 1998-10-30 | 2000-05-24 | Assistance Publique, Hopitaux De Paris | Use of melarsoprol for the manufacture of a medicament for treating B-cell lymphoproliferative diseases, such as multiple myeloma |
| US6191123B1 (en) | 1999-03-19 | 2001-02-20 | Parker Hughes Institute | Organic-arsenic compounds |
| AUPQ296799A0 (en) * | 1999-09-20 | 1999-10-14 | Unisearch Limited | A cell-membrane impermeable trivalent organoarsenical derivative and use thereof |
| DE60118172T2 (de) | 2000-04-26 | 2007-03-08 | Oregon Health Sciences University, Portland | Verabreichung von einer chemoschützenden verbindung,welche eine thiolgruppe enthält |
| AUPR379801A0 (en) | 2001-03-19 | 2001-04-12 | Unisearch Limited | Use of a substantially cell membrane impermeable compound for treating arthritis |
| AUPR598901A0 (en) | 2001-06-28 | 2001-07-19 | Unisearch Limited | Inhibition of angiogenesis by targeting protein tyrosine phosphatases |
| CA2417008A1 (en) | 2001-07-06 | 2003-01-16 | Cochlear Limited | Configuration of implanted devices |
| JP4571408B2 (ja) * | 2002-01-07 | 2010-10-27 | ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム | 癌治療薬としての、ｓ−ジメチルアルシノ−チオコハク酸、ｓ−ジメチルアルシノ−２−チオ安息香酸、ｓ−（ジメチルアルシノ）グルタチオン |
| ES2330519T3 (es) | 2002-11-07 | 2009-12-11 | Newsouth Innovations Pty Limited | Inducion de la transicion de permeabilidad mitocondrial. |
| TWI411431B (zh) | 2004-07-16 | 2013-10-11 | Texas A & M Univ Sys | 有機砷化合物、其用於治療癌症之用途及包含其之醫藥組成物 |
| JP5301449B2 (ja) | 2006-11-01 | 2013-09-25 | ニューサウス イノベイションズ ピーティーワイ リミテッド | 有機アルセノキシド化合物およびその使用 |
-
2003
- 2003-01-07 JP JP2003557380A patent/JP4571408B2/ja not_active Expired - Lifetime
- 2003-01-07 CA CA2472633A patent/CA2472633C/en not_active Expired - Fee Related
- 2003-01-07 EP EP11187256A patent/EP2462932A1/en not_active Withdrawn
- 2003-01-07 EP EP03705662.9A patent/EP1474128B1/en not_active Expired - Lifetime
- 2003-01-07 US US10/337,969 patent/US6911471B2/en not_active Expired - Lifetime
- 2003-01-07 WO PCT/US2003/000281 patent/WO2003057012A2/en active Application Filing
- 2003-01-07 EP EP20110187261 patent/EP2420229A1/en not_active Withdrawn
- 2003-01-07 AU AU2003207455A patent/AU2003207455B2/en not_active Ceased
-
2005
- 2005-01-13 US US11/035,178 patent/US6995188B2/en not_active Expired - Lifetime
-
2006
- 2006-02-06 US US11/349,043 patent/US7619000B2/en not_active Expired - Lifetime
-
2007
- 2007-08-20 US US11/894,807 patent/US20080090904A1/en not_active Abandoned
-
2009
- 2009-12-09 JP JP2009279362A patent/JP5603593B2/ja not_active Expired - Fee Related
-
2013
- 2013-08-22 JP JP2013172071A patent/JP2013237701A/ja active Pending
-
2015
- 2015-03-16 JP JP2015051753A patent/JP2015120745A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003057012A8 (en) | 2004-04-01 |
| AU2003207455B2 (en) | 2007-09-20 |
| JP2013237701A (ja) | 2013-11-28 |
| JP2005527487A (ja) | 2005-09-15 |
| EP2462932A1 (en) | 2012-06-13 |
| JP2015120745A (ja) | 2015-07-02 |
| US6995188B2 (en) | 2006-02-07 |
| AU2003207455A1 (en) | 2003-07-24 |
| US20040034095A1 (en) | 2004-02-19 |
| US20050131062A1 (en) | 2005-06-16 |
| EP1474128A4 (en) | 2006-05-03 |
| US20080090904A1 (en) | 2008-04-17 |
| EP2420229A1 (en) | 2012-02-22 |
| AU2003207455A2 (en) | 2003-07-24 |
| EP1474128A2 (en) | 2004-11-10 |
| WO2003057012A2 (en) | 2003-07-17 |
| JP2010090149A (ja) | 2010-04-22 |
| JP4571408B2 (ja) | 2010-10-27 |
| US7619000B2 (en) | 2009-11-17 |
| EP1474128B1 (en) | 2016-06-01 |
| JP5603593B2 (ja) | 2014-10-08 |
| US20060189687A1 (en) | 2006-08-24 |
| CA2472633A1 (en) | 2003-07-17 |
| US6911471B2 (en) | 2005-06-28 |
| WO2003057012A3 (en) | 2004-07-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20170109 |