CA2472270A1 - Utilisation de composes ayant l'activite biologique de peptides intestinaux vasoactifs pour le traitement de broncho-pneumopathie chronique obstructive - Google Patents
Utilisation de composes ayant l'activite biologique de peptides intestinaux vasoactifs pour le traitement de broncho-pneumopathie chronique obstructive Download PDFInfo
- Publication number
- CA2472270A1 CA2472270A1 CA002472270A CA2472270A CA2472270A1 CA 2472270 A1 CA2472270 A1 CA 2472270A1 CA 002472270 A CA002472270 A CA 002472270A CA 2472270 A CA2472270 A CA 2472270A CA 2472270 A1 CA2472270 A1 CA 2472270A1
- Authority
- CA
- Canada
- Prior art keywords
- lys
- tyr
- asp
- arg
- leu
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2278—Vasoactive intestinal peptide [VIP]; Related peptides (e.g. Exendin)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Vascular Medicine (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
L'invention concerne l'utilisation de peptides et de compositions pharmaceutiques contenant lesdits peptides, d'une haute activité biologique et pharmacologique en tant que médicaments thérapeutiques pour le traitement d'affections apparentées à une broncho-pneumopathie chronique obstructive (COPD), de préférence non en corrélation avec des symptômes d'hypertension pulmonaire. L'invention concerne en outre l'utilisation desdits peptides pour une autre maladie pulmonaire, à savoir, le syndrome respiratoire aigu sévère (ARDS). On a montré que les peptides connus se présentant à l'état naturel <= peptides intestinaux vasoactifs (VIP) >= et <= polypeptides d'activation adénylate cyclase pituitaires (PACAP) >=, ainsi que des analogues ou des dérivés de VIP et de PACAP pouvaient être utilisés avec succès pour le traitement des maladies précitées.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02001839 | 2002-01-26 | ||
| EP02001839.6 | 2002-01-26 | ||
| PCT/CH2003/000056 WO2003061680A2 (fr) | 2002-01-26 | 2003-01-23 | Utilisation de composes ayant l'activite biologique de peptides intestinaux vasoactifs pour le traitement de broncho-pneumopathie chronique obstructive |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2472270A1 true CA2472270A1 (fr) | 2003-07-31 |
Family
ID=27589068
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002472270A Abandoned CA2472270A1 (fr) | 2002-01-26 | 2003-01-23 | Utilisation de composes ayant l'activite biologique de peptides intestinaux vasoactifs pour le traitement de broncho-pneumopathie chronique obstructive |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1468021A2 (fr) |
| BR (1) | BR0302832A (fr) |
| CA (1) | CA2472270A1 (fr) |
| NO (1) | NO20034269L (fr) |
| WO (1) | WO2003061680A2 (fr) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2004255379B2 (en) | 2003-07-14 | 2007-08-16 | Mondobiotech Ag | Biologically active substance of a vasoactive intestinal peptide for treating interstitial lung infections |
| WO2005014030A1 (fr) * | 2003-07-24 | 2005-02-17 | Lutz-Henning Block | Technique de traitement de maladies pulmonaires associees a des erreurs de ventilation-perfusion |
| CA2574709A1 (fr) * | 2004-07-21 | 2006-02-02 | Tulane University Health Sciences Center | Traitement du dysfonctionnement renal et du myelome multiple a l'aide de composes pacap |
| WO2011054001A2 (fr) | 2009-11-02 | 2011-05-05 | The Administrators Of The Tulane | Analogues de polypeptide d'activation d'adénylate cyclase hypophysaire (pacap) et procédés pour leur utilisation |
| EP3583933A1 (fr) | 2018-06-20 | 2019-12-25 | Albert-Ludwigs-Universität Freiburg | Administration d'aviptadil par inhalation pour traiter la maladie chronique du béryllium |
| AU2020269901A1 (en) | 2019-05-07 | 2021-12-23 | Advita Lifescence GmbH | Vasoactive intestinal peptide (VIP) for use in the treatment of drug-induced pneumonitis |
| EP4232073B1 (fr) | 2020-12-04 | 2024-05-01 | Centurion Ilac Sanayi Ve Ticaret Anonim Sirketi | Nouveau régime posologique pour polypeptide intestinal vasoactif inhalé |
| US20240181014A1 (en) * | 2021-04-20 | 2024-06-06 | Advita Lifescience Ag | Use of aviptadil alone or in combination with alpha lipoic acid as a therapeutic medicament for post-viral infection syndrome |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5612314A (en) * | 1995-04-21 | 1997-03-18 | Brigham & Women's Hospital | Nitrosylated neuropeptides |
| GB9818548D0 (en) * | 1998-08-25 | 1998-10-21 | Microbiological Res Authority | Treatment of mucas hypersecretion |
| AU2072002A (en) * | 2000-11-28 | 2002-06-11 | Mondobiotech Sa | Compounds with the biological activity of vasoactive intestinal peptide for the treatment of pulmonary and arteriolar hypertension |
-
2003
- 2003-01-23 BR BR0302832-1A patent/BR0302832A/pt not_active Application Discontinuation
- 2003-01-23 WO PCT/CH2003/000056 patent/WO2003061680A2/fr not_active Application Discontinuation
- 2003-01-23 CA CA002472270A patent/CA2472270A1/fr not_active Abandoned
- 2003-01-23 EP EP03731651A patent/EP1468021A2/fr not_active Withdrawn
- 2003-09-24 NO NO20034269A patent/NO20034269L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NO20034269L (no) | 2003-11-26 |
| BR0302832A (pt) | 2004-04-27 |
| WO2003061680A3 (fr) | 2003-11-13 |
| EP1468021A2 (fr) | 2004-10-20 |
| WO2003061680A2 (fr) | 2003-07-31 |
| WO2003061680A9 (fr) | 2004-06-03 |
| NO20034269D0 (no) | 2003-09-24 |
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| AU2002220720A1 (en) | Compounds with the biological activity of vasoactive intestinal peptide for the treatment of pulmonary and arteriolar hypertension | |
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| CA2472270A1 (fr) | Utilisation de composes ayant l'activite biologique de peptides intestinaux vasoactifs pour le traitement de broncho-pneumopathie chronique obstructive | |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Dead |