CA2471376A1 - Polymorphismes nucleotidiques associes a l'osteoporose - Google Patents

Polymorphismes nucleotidiques associes a l'osteoporose Download PDF

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Publication number
CA2471376A1
CA2471376A1 CA002471376A CA2471376A CA2471376A1 CA 2471376 A1 CA2471376 A1 CA 2471376A1 CA 002471376 A CA002471376 A CA 002471376A CA 2471376 A CA2471376 A CA 2471376A CA 2471376 A1 CA2471376 A1 CA 2471376A1
Authority
CA
Canada
Prior art keywords
sequence
dna
protein
gene
polymorphism
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002471376A
Other languages
English (en)
Inventor
Karen Anne Jones
Ana Valdes
David J. Townley
Jonathan Mangion
Nicolas Galwey
Simon Bennett
Ian Mckay
Alan Schafer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Incyte Genomics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc filed Critical Incyte Genomics Inc
Publication of CA2471376A1 publication Critical patent/CA2471376A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La présente invention concerne des polynucléotides associés à la susceptibilité à une faible teneur minérale des os et/ou à la dégradation osseuse généralement associée à des maladies humaines telles que, en particulier, l'ostéoporose. L'invention se rapporte également à des polynucléotides polymorphes associés à l'ostéoporose. L'invention se rapporte à des procédés permettant de déterminer si un polymorphisme particulier prédispose un individu au développement de l'ostéoporose ou est associé à ce développement. L'invention se rapporte en outre à des procédés de détection de la présence d'un ou de plusieurs polymorphismes constituant des indicateurs de l'ostéoporose, ainsi qu'à l'utilisation des nouveaux polynucléotides décrits ci-dessus pour le développement de médicaments et le traitement de maladies.
CA002471376A 2001-12-20 2002-12-19 Polymorphismes nucleotidiques associes a l'osteoporose Abandoned CA2471376A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US34271101P 2001-12-20 2001-12-20
US60/342,711 2001-12-20
US42355902P 2002-11-04 2002-11-04
US60/423,559 2002-11-04
PCT/US2002/040948 WO2003054218A2 (fr) 2001-12-20 2002-12-19 Polymorphismes nucleotidiques associes a l'osteoporose

Publications (1)

Publication Number Publication Date
CA2471376A1 true CA2471376A1 (fr) 2003-07-03

Family

ID=26993153

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002471376A Abandoned CA2471376A1 (fr) 2001-12-20 2002-12-19 Polymorphismes nucleotidiques associes a l'osteoporose

Country Status (4)

Country Link
EP (1) EP1466012A2 (fr)
AU (1) AU2002366709A1 (fr)
CA (1) CA2471376A1 (fr)
WO (1) WO2003054218A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0301715D0 (en) * 2003-01-24 2003-02-26 King S College London Detection of predisposition to osteoporosis
WO2005005471A2 (fr) 2003-07-11 2005-01-20 Develogen Aktiengesellschaft Utilisation de produits des proteines dg153 ou dg177 secretees pour la prevention et le traitement de maladies du pancreas et/ou de l'obesite et/ou du syndrome metabolique
CA3116028A1 (fr) * 2018-10-09 2020-04-16 Genecentric Therapeutics, Inc. Detection d'une charge de mutation de tumeur avec un substrat d'arn

Also Published As

Publication number Publication date
WO2003054218A2 (fr) 2003-07-03
AU2002366709A8 (en) 2003-07-09
WO2003054218A3 (fr) 2004-02-19
AU2002366709A1 (en) 2003-07-09
EP1466012A2 (fr) 2004-10-13

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Legal Events

Date Code Title Description
FZDE Discontinued