CA2465051C - Appareil photodynamique commute - Google Patents
Appareil photodynamique commute Download PDFInfo
- Publication number
- CA2465051C CA2465051C CA2465051A CA2465051A CA2465051C CA 2465051 C CA2465051 C CA 2465051C CA 2465051 A CA2465051 A CA 2465051A CA 2465051 A CA2465051 A CA 2465051A CA 2465051 C CA2465051 C CA 2465051C
- Authority
- CA
- Canada
- Prior art keywords
- drug
- probes
- light
- laser
- probe
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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- 239000003814 drug Substances 0.000 claims abstract description 86
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- 230000003287 optical effect Effects 0.000 claims abstract description 57
- 231100000760 phototoxic Toxicity 0.000 claims abstract description 28
- 230000003213 activating effect Effects 0.000 claims abstract description 25
- 238000002428 photodynamic therapy Methods 0.000 claims abstract description 22
- 238000012512 characterization method Methods 0.000 claims abstract description 5
- 210000001519 tissue Anatomy 0.000 claims description 107
- 210000002307 prostate Anatomy 0.000 claims description 11
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- 229910052760 oxygen Inorganic materials 0.000 description 5
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- MHIITNFQDPFSES-UHFFFAOYSA-N 25,26,27,28-tetrazahexacyclo[16.6.1.13,6.18,11.113,16.019,24]octacosa-1(25),2,4,6,8(27),9,11,13,15,17,19,21,23-tridecaene Chemical compound N1C(C=C2C3=CC=CC=C3C(C=C3NC(=C4)C=C3)=N2)=CC=C1C=C1C=CC4=N1 MHIITNFQDPFSES-UHFFFAOYSA-N 0.000 description 2
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 description 2
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- 206010016717 Fistula Diseases 0.000 description 1
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- VANSZAOQCMTTPB-SETSBSEESA-N hypocrellin Chemical compound C1[C@@](C)(O)[C@@H](C(C)=O)C2=C(OC)C(O)=C3C(=O)C=C(OC)C4=C3C2=C2C3=C4C(OC)=CC(=O)C3=C(O)C(OC)=C21 VANSZAOQCMTTPB-SETSBSEESA-N 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 229940028435 intralipid Drugs 0.000 description 1
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- 238000004519 manufacturing process Methods 0.000 description 1
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- 210000000865 mononuclear phagocyte system Anatomy 0.000 description 1
- 230000010412 perfusion Effects 0.000 description 1
- 231100000737 phototoxin Toxicity 0.000 description 1
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- BQJKVFXDDMQLBE-UHFFFAOYSA-N shiraiachrome A Natural products COC1=C2C3=C(OC)C=C(O)C4=C3C3=C5C(CC(C)(O)C(C(C)=O)C3=C(OC)C4=O)=C(OC)C(=O)C(C(O)=C1)=C25 BQJKVFXDDMQLBE-UHFFFAOYSA-N 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/062—Photodynamic therapy, i.e. excitation of an agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0601—Apparatus for use inside the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00017—Electrical control of surgical instruments
- A61B2017/00022—Sensing or detecting at the treatment site
- A61B2017/00057—Light
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
- A61B2018/208—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser with multiple treatment beams not sharing a common path, e.g. non-axial or parallel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0601—Apparatus for use inside the body
- A61N2005/0612—Apparatus for use inside the body using probes penetrating tissue; interstitial probes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0626—Monitoring, verifying, controlling systems and methods
- A61N2005/0629—Sequential activation of light sources
Abstract
Un appareil de thérapie photodynamique et une méthode dans laquelle (1) un médicament phototoxique est fourni à l'apport artériel d'un tissu ciblé, (2) la présence d'un éclairage d'activation de médicament au tissu ciblé fournie par des sondes est contrôlée par la sélection séquentielle du fonctionnement des sondes, (3) une sonde de rayonnement automatique est utilisée pour la caractérisation optique efficace du tissu ciblé et (4) une dose optique est surveillée par la sélection séquentielle des sondes comme émetteurs et récepteurs.
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/830,868 US20040267335A1 (en) | 2003-04-23 | 2004-04-23 | Switched photodynamic therapy apparatus and method |
CA2465051A CA2465051C (fr) | 2003-04-23 | 2004-04-23 | Appareil photodynamique commute |
EP04252402A EP1470837A3 (fr) | 2003-04-23 | 2004-04-23 | Appareil et procédé pour la thérapie photodynamique commutée |
US11/416,995 US20060282136A1 (en) | 2003-04-23 | 2006-05-03 | Switched photodynamic therapy apparatus and method |
US11/770,670 US20080033339A1 (en) | 2003-04-23 | 2007-06-28 | Switched photodynamic therapy apparatus and method |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US46465603P | 2003-04-23 | 2003-04-23 | |
CA2465051A CA2465051C (fr) | 2003-04-23 | 2004-04-23 | Appareil photodynamique commute |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2465051A1 CA2465051A1 (fr) | 2005-10-23 |
CA2465051C true CA2465051C (fr) | 2014-11-18 |
Family
ID=37762413
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2465051A Expired - Lifetime CA2465051C (fr) | 2003-04-23 | 2004-04-23 | Appareil photodynamique commute |
Country Status (3)
Country | Link |
---|---|
US (3) | US20040267335A1 (fr) |
EP (1) | EP1470837A3 (fr) |
CA (1) | CA2465051C (fr) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20080082090A1 (en) * | 2004-04-01 | 2008-04-03 | The General Hospital Corporation | Method and apparatus for dermatological treatment and tissue reshaping |
EP1742588B1 (fr) | 2004-04-01 | 2016-10-19 | The General Hospital Corporation | Appareil de traitement dermatologique et remodelage de tissus |
US20060095095A1 (en) * | 2004-11-03 | 2006-05-04 | Cao Group, Inc. | Cancer treatment using laser |
US7976571B2 (en) * | 2005-08-02 | 2011-07-12 | Wolfgang Neuberger | Photodynamic therapy irradiation system for the treatment of superficial hyperproliferative tissue growth |
US20080071256A1 (en) * | 2005-08-23 | 2008-03-20 | Densen Cao | Cancer treatment using low energy lasers |
US20070265607A1 (en) * | 2005-08-23 | 2007-11-15 | Densen Cao | Cancer treatment using low energy lasers |
HRP20060149B1 (en) | 2006-04-19 | 2008-11-30 | Institut "Ruđer Bošković" | Intelligent sequential illuminator photodynamic therapy |
JP5472987B2 (ja) * | 2006-08-15 | 2014-04-16 | スペクトラキュアー アーベー | 組織内光線力学的光線治療パラメータを制御し、且つ、調整するためのシステム及び方法 |
US8582841B2 (en) | 2006-08-15 | 2013-11-12 | Spectracure Ab | System and method for pre-treatment planning of photodynamic light therapy |
US20130046357A1 (en) * | 2008-03-27 | 2013-02-21 | Joseph Neev | Tissue or nerve treatment device and method |
WO2008152076A2 (fr) * | 2007-06-11 | 2008-12-18 | Spectracure Ab | Système et procédé pour commande de rétroaction de tomographie optique de dosimétrie pour une thérapie photodynamique (pdt) |
WO2009116029A2 (fr) * | 2008-03-17 | 2009-09-24 | Or-Nim Medical Ltd. | Appareil de surveillance optique non invasif |
US9370306B1 (en) | 2008-08-13 | 2016-06-21 | Abbott Cardiovascular System Inc. | Methods and devices for in vivo targeted light therapy |
US8170657B1 (en) | 2008-08-13 | 2012-05-01 | Abbott Cadiovascular Systems Inc. | Delivery catheters for light activated agents |
US9358369B1 (en) | 2008-08-13 | 2016-06-07 | Abbott Cardiovascular Systems Inc. | Reduced profile and enhanced flexibility delivery catheters for light activated agents |
EP2403597A1 (fr) * | 2009-02-09 | 2012-01-11 | SpectraCure AB | Système et procédé pour la planification prétraitement d'une luminothérapie photodynamique |
JP5641773B2 (ja) * | 2010-04-28 | 2014-12-17 | キヤノン株式会社 | 測定装置 |
WO2012076631A1 (fr) | 2010-12-07 | 2012-06-14 | Spectracure Ab | Système et procédé de photothérapie photodynamique interstitielle en combinaison avec des photosensibilisateurs |
EP3325096B1 (fr) * | 2015-07-23 | 2023-09-06 | Health Research, Inc. | Système d'administration d'une lumière dosée à un tissu |
WO2017216371A1 (fr) * | 2016-06-17 | 2017-12-21 | Gensight Biologics | Dispositif d'éclairage d'un objet avec une intensité lumineuse contrôlée et procédé associé |
US11599994B2 (en) * | 2019-03-28 | 2023-03-07 | Purdue Research Foundation | System and methods for clear optimally matched panoramic channel technique for deep brain photonic interface |
EP3718600A1 (fr) | 2019-04-04 | 2020-10-07 | SpectraCure AB | Système et procédé permettant de déterminer l'atténuation de la lumière au niveau d'éléments optiques insérés dans un tissu |
EP4146073A2 (fr) * | 2020-05-05 | 2023-03-15 | Lumeda Inc. | Système et procédé de dosimétrie multiplexée dans le temps |
CN112451862B (zh) * | 2020-11-24 | 2023-03-28 | 深圳罗兹曼国际转化医学研究院 | 光动力治疗系统及其控制方法 |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5445608A (en) * | 1993-08-16 | 1995-08-29 | James C. Chen | Method and apparatus for providing light-activated therapy |
US5571083A (en) * | 1994-02-18 | 1996-11-05 | Lemelson; Jerome H. | Method and system for cell transplantation |
US5454782A (en) * | 1994-08-11 | 1995-10-03 | Perkins; Rodney C. | Translumenal circumferential energy delivery device |
AT403990B (de) * | 1995-11-24 | 1998-07-27 | Nagypal Tibor Dipl Ing Dr | Gerät zur photodynamischen behandlung von lebewesen bzw. organen derselben |
US6373573B1 (en) * | 2000-03-13 | 2002-04-16 | Lj Laboratories L.L.C. | Apparatus for measuring optical characteristics of a substrate and pigments applied thereto |
US5702432A (en) * | 1996-10-03 | 1997-12-30 | Light Sciences Limited Partnership | Intracorporeal light treatment of blood |
US6058323A (en) * | 1996-11-05 | 2000-05-02 | Lemelson; Jerome | System and method for treating select tissue in a living being |
US6058937A (en) * | 1997-07-18 | 2000-05-09 | Miravant Systems, Inc. | Photodynamic Therapy of highly vascularized tissue |
US6128525A (en) * | 1997-07-29 | 2000-10-03 | Zeng; Haishan | Apparatus and method to monitor photodynamic therapy (PDT) |
US6175669B1 (en) * | 1998-03-30 | 2001-01-16 | The Regents Of The Universtiy Of California | Optical coherence domain reflectometry guidewire |
US6416531B2 (en) * | 1998-06-24 | 2002-07-09 | Light Sciences Corporation | Application of light at plural treatment sites within a tumor to increase the efficacy of light therapy |
US6377842B1 (en) * | 1998-09-22 | 2002-04-23 | Aurora Optics, Inc. | Method for quantitative measurement of fluorescent and phosphorescent drugs within tissue utilizing a fiber optic probe |
US6344050B1 (en) * | 1998-12-21 | 2002-02-05 | Light Sciences Corporation | Use of pegylated photosensitizer conjugated with an antibody for treating abnormal tissue |
US6602274B1 (en) * | 1999-01-15 | 2003-08-05 | Light Sciences Corporation | Targeted transcutaneous cancer therapy |
US6238426B1 (en) * | 1999-07-19 | 2001-05-29 | Light Sciences Corporation | Real-time monitoring of photodynamic therapy over an extended time |
US20040044304A1 (en) * | 2000-01-21 | 2004-03-04 | Hill John S | Local drug delivery using photosensitizer-mediated and electromagnetic radiation enhanced vascular permeability |
US20020095197A1 (en) * | 2000-07-11 | 2002-07-18 | Lardo Albert C. | Application of photochemotherapy for the treatment of cardiac arrhythmias |
US6524330B1 (en) * | 2000-10-27 | 2003-02-25 | Bahram Khoobehi | Method of ocular treatment |
US7383076B2 (en) * | 2000-11-27 | 2008-06-03 | The General Hospital Corporation | Fluorescence-mediated molecular tomography |
US6615063B1 (en) * | 2000-11-27 | 2003-09-02 | The General Hospital Corporation | Fluorescence-mediated molecular tomography |
JP2002215192A (ja) * | 2001-01-17 | 2002-07-31 | Nec Corp | オーディオ情報処理装置及び処理方法 |
US6629969B2 (en) * | 2001-07-26 | 2003-10-07 | Durect Corporation | Catheter for modification of agent formulation |
SE522697C2 (sv) * | 2001-11-14 | 2004-03-02 | Spectracure Ab | Terapi- och diagnossystem med fördelare för distribution av strålning |
CA2473924A1 (fr) * | 2002-01-23 | 2003-07-31 | Light Sciences Corporation | Systemes et procedes pour une therapie photodynamique |
US20040147501A1 (en) * | 2002-07-08 | 2004-07-29 | Dolmans Dennis E.J.G.J. | Photodynamic therapy |
-
2004
- 2004-04-23 EP EP04252402A patent/EP1470837A3/fr not_active Withdrawn
- 2004-04-23 US US10/830,868 patent/US20040267335A1/en not_active Abandoned
- 2004-04-23 CA CA2465051A patent/CA2465051C/fr not_active Expired - Lifetime
-
2006
- 2006-05-03 US US11/416,995 patent/US20060282136A1/en not_active Abandoned
-
2007
- 2007-06-28 US US11/770,670 patent/US20080033339A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20080033339A1 (en) | 2008-02-07 |
EP1470837A2 (fr) | 2004-10-27 |
EP1470837A3 (fr) | 2005-08-10 |
CA2465051A1 (fr) | 2005-10-23 |
US20060282136A1 (en) | 2006-12-14 |
US20040267335A1 (en) | 2004-12-30 |
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Legal Events
Date | Code | Title | Description |
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EEER | Examination request |