CA2462717C - Supercritical fluid extraction process for tissue preparation - Google Patents

Supercritical fluid extraction process for tissue preparation Download PDF

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Publication number
CA2462717C
CA2462717C CA2462717A CA2462717A CA2462717C CA 2462717 C CA2462717 C CA 2462717C CA 2462717 A CA2462717 A CA 2462717A CA 2462717 A CA2462717 A CA 2462717A CA 2462717 C CA2462717 C CA 2462717C
Authority
CA
Canada
Prior art keywords
tissue
carbon dioxide
supercritical
mammalian soft
mammalian
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA2462717A
Other languages
English (en)
French (fr)
Other versions
CA2462717A1 (en
Inventor
Ralph Kafesjian
Myron J. Howanec
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Edwards Lifesciences Corp
Original Assignee
Edwards Lifesciences Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Edwards Lifesciences Corp filed Critical Edwards Lifesciences Corp
Publication of CA2462717A1 publication Critical patent/CA2462717A1/en
Application granted granted Critical
Publication of CA2462717C publication Critical patent/CA2462717C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/16—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using chemical substances
    • A61L2/18—Liquid substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/16—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using chemical substances
    • A61L2/20—Gaseous substances, e.g. vapours
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00—Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05—Living organisms or biological materials
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00—Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/915—Method or apparatus for preparing biological material

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Botany (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Urology & Nephrology (AREA)
  • Zoology (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Extraction Or Liquid Replacement (AREA)
CA2462717A 2001-10-17 2002-10-04 Supercritical fluid extraction process for tissue preparation Expired - Lifetime CA2462717C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/981,274 2001-10-17
US09/981,274 US7008591B2 (en) 2001-10-17 2001-10-17 Supercritical fluid extraction process for tissue preparation
PCT/US2002/032027 WO2003033035A1 (en) 2001-10-17 2002-10-04 Supercritical fluid extraction process for tissue preparation

Publications (2)

Publication Number Publication Date
CA2462717A1 CA2462717A1 (en) 2003-04-24
CA2462717C true CA2462717C (en) 2010-09-28

Family

ID=25528256

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2462717A Expired - Lifetime CA2462717C (en) 2001-10-17 2002-10-04 Supercritical fluid extraction process for tissue preparation

Country Status (5)

Country Link
US (1) US7008591B2 (https=)
EP (1) EP1436016A1 (https=)
JP (1) JP2005506173A (https=)
CA (1) CA2462717C (https=)
WO (1) WO2003033035A1 (https=)

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US8034288B2 (en) * 2003-06-23 2011-10-11 Novasterilis Method and apparatus for cleaning of viable donor soft tissue
WO2005000364A2 (en) * 2003-06-23 2005-01-06 Novasterilis Inc. Sterilization methods and apparatus which employ additive-containing supercritical carbon dioxide sterilant
US8974730B2 (en) 2003-06-23 2015-03-10 Novasterilis, Inc. Process for creating acellular viable donor soft tissue
NZ544311A (en) * 2003-06-30 2008-12-24 Groningen Acad Ziekenhuis Method for histoprocessing
WO2005065396A2 (en) 2003-12-31 2005-07-21 Osteotech, Inc. Improved bone matrix compositions and methods
US20070231788A1 (en) * 2003-12-31 2007-10-04 Keyvan Behnam Method for In Vitro Assay of Demineralized Bone Matrix
TWI302944B (en) * 2004-07-12 2008-11-11 Method for removing virus activity from biological materials
US7422607B2 (en) * 2004-08-24 2008-09-09 Oviatt Henry W Anti-calcification treatments for heart valves and vascular grafts
FR2891052B1 (fr) * 2005-09-21 2007-12-21 Histolex Soc Responsabilite Li Procede de preparation d'un echantillon
CN101365499A (zh) * 2005-11-01 2009-02-11 骨骼技术股份有限公司 骨基质组合物和方法
US7666369B2 (en) * 2006-09-29 2010-02-23 Tyco Healthcare Group Lp System and method for recycling sterilant gas
US8268238B2 (en) * 2006-09-29 2012-09-18 Tyco Healthcare Group Lp System and method for recycling sterilant gas
US9173967B1 (en) 2007-05-11 2015-11-03 SDCmaterials, Inc. System for and method of processing soft tissue and skin with fluids using temperature and pressure changes
US20100323440A1 (en) * 2007-06-12 2010-12-23 Musculoskeletal Transplant Foundation Process for sterilizing acellular soft tissue under pressure
CA2690457C (en) 2007-06-15 2018-02-20 Osteotech, Inc. Bone matrix compositions and methods
WO2008157492A2 (en) * 2007-06-15 2008-12-24 Osteotech, Inc. Osteoinductive demineralized cancellous bone
US9554920B2 (en) 2007-06-15 2017-01-31 Warsaw Orthopedic, Inc. Bone matrix compositions having nanoscale textured surfaces
CA3062443C (en) * 2007-06-15 2022-03-15 Warsaw Orthopedic, Inc. Method of treating tissue
US20110054408A1 (en) * 2007-07-10 2011-03-03 Guobao Wei Delivery systems, devices, tools, and methods of use
WO2009009684A1 (en) * 2007-07-10 2009-01-15 Osteotech, Inc. Delivery system
US8507401B1 (en) 2007-10-15 2013-08-13 SDCmaterials, Inc. Method and system for forming plug and play metal catalysts
US8202539B2 (en) * 2007-10-19 2012-06-19 Warsaw Orthopedic, Inc. Demineralized bone matrix compositions and methods
WO2010093959A2 (en) 2009-02-12 2010-08-19 Osteotech, Inc. Delivery systems, tools, and methods of use
CA2770490C (en) * 2009-08-11 2024-04-16 The Johns Hopkins University Compositions and methods for implantation of processed adipose tissue and processed adipose tissue products
EP2475405B1 (en) 2009-09-09 2016-04-13 Cook Medical Technologies LLC Substrate surface modification utilizing a densified fluid and a surface modifier
US10130736B1 (en) 2010-05-14 2018-11-20 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US8883210B1 (en) 2010-05-14 2014-11-11 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US9352003B1 (en) 2010-05-14 2016-05-31 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US8834928B1 (en) 2011-05-16 2014-09-16 Musculoskeletal Transplant Foundation Tissue-derived tissugenic implants, and methods of fabricating and using same
US20130079494A1 (en) * 2011-09-22 2013-03-28 Tyco Healthcare Group Lp Processing Tissue Utilizing Supercritical Fluid
US8563234B2 (en) * 2012-02-23 2013-10-22 Anastasios J. Tousimis Critical point drying systems and methods for in situ tissue preservation
US8956566B2 (en) 2012-03-12 2015-02-17 Pure Biosolutions, Llc System and method for virus inactivation
CN102755665A (zh) * 2012-07-31 2012-10-31 中国辐射防护研究院 一种异种骨移植材料的制备方法
US20150037436A1 (en) 2013-07-30 2015-02-05 Musculoskeletal Transplant Foundation Acellular soft tissue-derived matrices and methods for preparing same
US20150258245A1 (en) * 2014-03-13 2015-09-17 Warsaw Orthopedic. Inc. Method of delipidation and/or terminal sterilization for bone material
CA2986702C (en) 2015-05-21 2023-04-04 David Wang Modified demineralized cortical bone fibers
US10912864B2 (en) 2015-07-24 2021-02-09 Musculoskeletal Transplant Foundation Acellular soft tissue-derived matrices and methods for preparing same
US11185610B2 (en) * 2015-08-11 2021-11-30 Acro Biomedical Company. Ltd. Preparation of acellular cartilage graft and uses thereof
US11052175B2 (en) 2015-08-19 2021-07-06 Musculoskeletal Transplant Foundation Cartilage-derived implants and methods of making and using same
US20180353630A1 (en) * 2015-12-24 2018-12-13 Crititech, Inc. System and Methods for Tissue Sterilization
WO2017118266A1 (en) * 2016-01-08 2017-07-13 Chen Shing-Jye Acellular corneas, methods of producing the same and uses thereof
WO2018031265A1 (en) * 2016-08-08 2018-02-15 Allosource Supercritical carbon dioxide tissue processing methods
KR101954905B1 (ko) * 2016-08-08 2019-03-08 주식회사 도프 지방흡입 유출물로부터 초임계공정을 이용하여 콜라겐을 분리하는 방법
WO2018030748A1 (ko) * 2016-08-08 2018-02-15 주식회사 도프 지방흡입 유출물로부터 초임계공정을 이용하여 콜라겐을 분리하는 방법
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US20240173443A1 (en) 2022-11-25 2024-05-30 InnovMedics, LLC Sterilizing biological tissue with supercritical carbon dioxide

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Also Published As

Publication number Publication date
JP2005506173A (ja) 2005-03-03
US7008591B2 (en) 2006-03-07
WO2003033035A1 (en) 2003-04-24
CA2462717A1 (en) 2003-04-24
EP1436016A1 (en) 2004-07-14
US20030072677A1 (en) 2003-04-17

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Effective date: 20221004