CA2444377A1 - Procede d'injection intradermique de substances - Google Patents

Procede d'injection intradermique de substances Download PDF

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Publication number
CA2444377A1
CA2444377A1 CA002444377A CA2444377A CA2444377A1 CA 2444377 A1 CA2444377 A1 CA 2444377A1 CA 002444377 A CA002444377 A CA 002444377A CA 2444377 A CA2444377 A CA 2444377A CA 2444377 A1 CA2444377 A1 CA 2444377A1
Authority
CA
Canada
Prior art keywords
substance
skin
needle
needle cannula
tip
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002444377A
Other languages
English (en)
Other versions
CA2444377C (fr
Inventor
Paul G. Alchas
Philippe Emile Fernand Laurent
John A. Mikszta
Jason Brent Alarcon
Phil G. Green
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2444377A1 publication Critical patent/CA2444377A1/fr
Application granted granted Critical
Publication of CA2444377C publication Critical patent/CA2444377C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/46—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for controlling depth of insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M2005/3103—Leak prevention means for distal end of syringes, i.e. syringe end for mounting a needle
    • A61M2005/3104—Caps for syringes without needle

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

L'invention concerne un procédé de préparation d'une injection intradermique au moyen d'un dispositif d'administration de médicament contenant la substance à injecter. L'invention concerne aussi un dispositif destiné à mettre en oeuvre le procédé comportant une canule à aiguille qui possède une pointe avant et une portion de limitation comportant une surface de mise en prise avec la peau qui entoure la canule à aiguille. Cette canule à aiguille est en communication fluidique avec la substance et la pointe de la canule à aiguille s'étend au delà de la surface de mise en prise avec la peau à une distance approximativement comprise entre 0,5 et 3 mm. Selon l'invention, elle comporte un angle d'orientation fixe par rapport au plan de la surface de mise en prise avec la peau. Cette surface de mise en prise avec la peau limite la pénétration de la pointe de l'aiguille dans la peau de manière que la substance puisse être expulsée à travers la pointe de l'aiguille dans la couche dermique. De préférence, l'angle d'orientation fixe de la canule à aiguille est perpendiculaire à la surface de la peau, et la surface de mise en prise avec la peau est généralement plate.
CA2444377A 2001-04-13 2001-04-13 Procede d'injection intradermique de substances Expired - Lifetime CA2444377C (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2001/012251 WO2002083216A1 (fr) 2001-04-13 2001-04-13 Procede d'injection intradermique de substances

Publications (2)

Publication Number Publication Date
CA2444377A1 true CA2444377A1 (fr) 2002-10-24
CA2444377C CA2444377C (fr) 2014-09-02

Family

ID=21742508

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2444377A Expired - Lifetime CA2444377C (fr) 2001-04-13 2001-04-13 Procede d'injection intradermique de substances

Country Status (7)

Country Link
EP (1) EP1381415A1 (fr)
JP (1) JP2004528896A (fr)
CN (1) CN1520320A (fr)
BR (1) BR0116973A (fr)
CA (1) CA2444377C (fr)
MX (1) MXPA03009369A (fr)
WO (1) WO2002083216A1 (fr)

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CA2451816A1 (fr) * 2001-06-29 2003-01-09 Becton, Dickinson And Company Distribution intradermique de vaccins et d'agents therapeutiques geniques via une microcannule
EP1476210B1 (fr) 2002-02-11 2008-09-24 Antares Pharma, Inc. Injecteur intradermique
JP2007517768A (ja) * 2003-05-06 2007-07-05 ベクトン・ディキンソン・アンド・カンパニー インスリンの薬物動態を変化させる方法
WO2006079064A1 (fr) 2005-01-24 2006-07-27 Antares Pharma, Inc. Injecteur a seringue preremplie assiste d'une aiguille
MX2008010258A (es) 2006-02-09 2008-10-01 Aderans Res Inst Inc Aparato y metodos para suministrar fluido y material a un sujeto.
WO2007131013A1 (fr) 2006-05-03 2007-11-15 Antares Pharma, Inc. Injecteur de reconstitution à deux étages
US9144648B2 (en) 2006-05-03 2015-09-29 Antares Pharma, Inc. Injector with adjustable dosing
US20080312661A1 (en) * 2007-06-12 2008-12-18 Downer David A Lens Injector Lumen Tip for Wound Assisted Delivery
ES2566542T3 (es) 2008-02-07 2016-04-13 Novartis Ag Cartucho de sistema de suministro de lente
US8814834B2 (en) 2008-03-10 2014-08-26 Antares Pharma, Inc. Injector safety device
CA2732812C (fr) 2008-08-05 2017-10-31 Antares Pharma, Inc. Injecteur a dosage multiple
BRPI0922213B8 (pt) * 2008-12-08 2021-06-22 Program For Appropriate Tech In Health alinhamento de uma agulha em um dispositivo de injeção intradérmica
TWI449551B (zh) * 2009-01-30 2014-08-21 Terumo Corp 注射針組合體以及藥劑注射裝置
JP5732039B2 (ja) 2009-03-20 2015-06-10 アンタレス・ファーマ・インコーポレーテッド 危険有害性薬剤の注入システム
CN104606745B (zh) * 2009-07-23 2017-07-28 适宜卫生科技项目公司 皮内注射适配器、皮内注射组件和皮内注射输送的注射器组件
EP2489379B1 (fr) 2011-01-21 2020-09-23 SID Technologies, LLC Adaptateur de stylo intradermique
US9220660B2 (en) 2011-07-15 2015-12-29 Antares Pharma, Inc. Liquid-transfer adapter beveled spike
US8496619B2 (en) 2011-07-15 2013-07-30 Antares Pharma, Inc. Injection device with cammed ram assembly
ES2562838T3 (es) 2012-01-31 2016-03-08 Trichoscience Innovations Inc. Dispositivos de inyección
KR20150003179A (ko) 2012-03-06 2015-01-08 안타레스 팔마, 인코퍼레이티드 분리력 특징을 가진 사전충전형 주사기
KR20150011346A (ko) 2012-04-06 2015-01-30 안타레스 팔마, 인코퍼레이티드 테스토스테론 조성물의 바늘-보조식 젯 주입 투여 장치 및 방법
US9364611B2 (en) 2012-05-07 2016-06-14 Antares Pharma, Inc. Needle assisted jet injection device having reduced trigger force
US9463089B2 (en) 2012-05-21 2016-10-11 Novartis Ag Plunger system for intraocular lens surgery
PT2953667T (pt) 2013-02-11 2020-01-28 Antares Pharma Inc Dispositivo de injeção a jato auxiliado por agulha tendo força de gatilho reduzida
JP6030803B2 (ja) 2013-03-11 2016-11-24 アンタレス・ファーマ・インコーポレーテッド ピニオンシステムを有する用量注射器
WO2014165136A1 (fr) 2013-03-12 2014-10-09 Antares Pharma, Inc. Seringues pré-remplies à volume constant et leurs trousses
EP2968071B1 (fr) * 2013-03-15 2021-08-04 Rani Therapeutics, LLC Dispositif pour l'administration orale de composés thérapeutiques
WO2014155536A1 (fr) * 2013-03-26 2014-10-02 テルモ株式会社 Capuchon élastique et ensemble seringue doté de celui-ci
US9474865B2 (en) 2013-04-25 2016-10-25 West Pharmaceutical Services, Inc. Needle shield for disposable syringe with annular ring
EP3041505A4 (fr) 2013-09-05 2017-04-19 Merck Sharp & Dohme Corp. Procédés d'immunisation par l'antigène du virus varicelle-zona
TWI689326B (zh) 2014-08-06 2020-04-01 加拿大商複製細胞生命科學公司 注射裝置
US10588780B2 (en) 2015-03-04 2020-03-17 Alcon Inc. Intraocular lens injector
EP4278996A3 (fr) 2015-06-03 2024-01-24 i2o Therapeutics, Inc. Systèmes de mise en place d'implant
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
US11000367B2 (en) 2017-01-13 2021-05-11 Alcon Inc. Intraocular lens injector
CN107287268A (zh) * 2017-06-16 2017-10-24 南京佰泰克生物技术有限公司 一种增强hiv‑1核酸疫苗免疫原性的佐剂
USD933219S1 (en) 2018-07-13 2021-10-12 Intarcia Therapeutics, Inc. Implant removal tool and assembly

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2664086A (en) * 1950-08-15 1953-12-29 Gerald O Transue Automatic injector for hypodermic needles
GB725024A (en) * 1952-11-07 1955-03-02 Lilly Co Eli Improvements in or relating to closure member for a syringe
US5279585A (en) 1992-02-04 1994-01-18 Becton, Dickinson And Company Medication delivery pen having improved dose delivery features
US5373684A (en) 1992-12-14 1994-12-20 Mallinckrodt Medical, Inc. Process and apparatus used in producing prefilled, sterile delivery devices
US5620425A (en) 1993-11-03 1997-04-15 Bracco International B.V. Method for the preparation of pre-filled plastic syringes
US5597530A (en) 1994-08-18 1997-01-28 Abbott Laboratories Process for prefilling and terminally sterilizing syringes
US5537042A (en) 1994-11-18 1996-07-16 Eldec Corporation Method and system for unobtrusively measuring physical properties in electrochemical processes
WO1999025402A1 (fr) * 1997-11-19 1999-05-27 Medico Development Investment Company Configuration d'aiguille
DE69914725T2 (de) 1998-03-13 2004-12-02 Becton, Dickinson And Co. Verfahren zum zusammensetzen und verpacken von medizinischen vorrichtungen
WO2000009135A1 (fr) 1998-08-14 2000-02-24 Toray Industries, Inc. Agents de protection des cellules péridermiques
US6494865B1 (en) * 1999-10-14 2002-12-17 Becton Dickinson And Company Intradermal delivery device including a needle assembly

Also Published As

Publication number Publication date
WO2002083216A1 (fr) 2002-10-24
CN1520320A (zh) 2004-08-11
CA2444377C (fr) 2014-09-02
EP1381415A1 (fr) 2004-01-21
JP2004528896A (ja) 2004-09-24
BR0116973A (pt) 2004-10-13
MXPA03009369A (es) 2004-01-29

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MKEX Expiry

Effective date: 20210413