CA2424567A1 - Procede destine a modifier des fragments de sucre - Google Patents

Procede destine a modifier des fragments de sucre Download PDF

Info

Publication number
CA2424567A1
CA2424567A1 CA002424567A CA2424567A CA2424567A1 CA 2424567 A1 CA2424567 A1 CA 2424567A1 CA 002424567 A CA002424567 A CA 002424567A CA 2424567 A CA2424567 A CA 2424567A CA 2424567 A1 CA2424567 A1 CA 2424567A1
Authority
CA
Canada
Prior art keywords
ala
leu
gly
val
arg
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002424567A
Other languages
English (en)
Inventor
Hung-Wen Liu
David H. Sherman
Lishan Zhao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Minnesota
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2424567A1 publication Critical patent/CA2424567A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates
    • C12P19/28N-glycosides
    • C12P19/30Nucleotides
    • C12P19/305Pyrimidine nucleotides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/60Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Oncology (AREA)
  • Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne un procédé destiné à modifier la structure de sucres.
CA002424567A 2000-10-05 2001-10-05 Procede destine a modifier des fragments de sucre Abandoned CA2424567A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23818500P 2000-10-05 2000-10-05
US60/238,185 2000-10-05
PCT/US2001/031255 WO2002029035A2 (fr) 2000-10-05 2001-10-05 Procede destine a modifier des fragments de sucre

Publications (1)

Publication Number Publication Date
CA2424567A1 true CA2424567A1 (fr) 2002-04-11

Family

ID=22896833

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002424567A Abandoned CA2424567A1 (fr) 2000-10-05 2001-10-05 Procede destine a modifier des fragments de sucre

Country Status (5)

Country Link
EP (1) EP1325134A2 (fr)
JP (1) JP2004534502A (fr)
AU (1) AU2001296652A1 (fr)
CA (1) CA2424567A1 (fr)
WO (1) WO2002029035A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109593740B (zh) * 2018-12-07 2021-01-29 广东省微生物研究所(广东省微生物分析检测中心) 一种糖基转移酶及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5998194A (en) * 1995-12-21 1999-12-07 Abbott Laboratories Polyketide-associated sugar biosynthesis genes
JP2001511349A (ja) * 1997-07-25 2001-08-14 ヘキスト・マリオン・ルセル Saccharopolysporaerythraea及びStreptomycesantibioticusにおける6−デオキシヘキソースの生合成及び移送のための遺伝子
US6265202B1 (en) * 1998-06-26 2001-07-24 Regents Of The University Of Minnesota DNA encoding methymycin and pikromycin

Also Published As

Publication number Publication date
AU2001296652A1 (en) 2002-04-15
WO2002029035A2 (fr) 2002-04-11
WO2002029035A3 (fr) 2003-01-30
JP2004534502A (ja) 2004-11-18
EP1325134A2 (fr) 2003-07-09

Similar Documents

Publication Publication Date Title
Aguirrezabalaga et al. Identification and Expression of Genes Involved in Biosynthesis of l-Oleandrose and Its Intermediatel-Olivose in the Oleandomycin Producer Streptomyces antibioticus
Wohlert et al. Insights about the biosynthesis of the avermectin deoxysugar L-oleandrose through heterologous expression of Streptomyces avermitilis deoxysugar genes in Streptomyces lividans
US6251636B1 (en) Recombinant oleandolide polyketide synthase
EP1244800B1 (fr) Analogues de la rapamycine
EP1224317B1 (fr) Production de polyc tides
CA2332129A1 (fr) Adn codant pour la methymycine et la pikromycine
JP5037771B2 (ja) グリコシル化されたハイブリッド産物およびその産生方法と利用
JP2004513605A (ja) 組換えメガロミシン生合成遺伝子およびその使用
JP2002516090A (ja) 組換えナルボノライドポリケチドシンターゼ
US20070059689A1 (en) Hybrid glycosylated products and their production and use
EP1414969B1 (fr) Genes biosynthetiques destines a la production d'un insecticide de butenyle-spinosyne
Tornus et al. Identification of four genes from the granaticin biosynthetic gene cluster of Streptomyces violaceoruber Tü22 involved in the biosynthesis of L-rhodinose
EP1412497A2 (fr) Biosynthese modifiee de polyenes
CA2424567A1 (fr) Procede destine a modifier des fragments de sucre
Lombó et al. Sugar biosynthesis and modification
US20040161839A1 (en) Method to alter sugar moieties
US20040214276A1 (en) Production of glycosylated macrolides in E. coli
Pelzer et al. Tool-box: tailoring enzymes for bio-combinatorial lead development and as markers for genome-based natural product lead discovery
KR101721750B1 (ko) 신규 마크로락탐 글리코시드 유도체, 이의 화학효소적 제조방법 및 이를 포함하는 항균용 조성물
Pageni et al. Characterization of a chalcosyltransferase (gerGTII) in dihydrochalcomycin biosynthesis
Méndez et al. Engineering glycosylation in bioactive compounds by combinatorial biosynthesis
Bechthold et al. Glycosylation of Secondary Metabolites To Produce Novel Compounds
Bilyk Exploring chemical diversity of angucycline antibiotics: molecular basis of simocyclinone and grecocycline biosynthesis
Murrell Investigation of sugar biosynthesis pathways of antitumor antibiotics C-1027 and bleomycin

Legal Events

Date Code Title Description
FZDE Dead