CA2416201A1 - Couches composites de phosphate de calcium bioactives deposees electrochimiquement sur des implants - Google Patents

Couches composites de phosphate de calcium bioactives deposees electrochimiquement sur des implants Download PDF

Info

Publication number
CA2416201A1
CA2416201A1 CA002416201A CA2416201A CA2416201A1 CA 2416201 A1 CA2416201 A1 CA 2416201A1 CA 002416201 A CA002416201 A CA 002416201A CA 2416201 A CA2416201 A CA 2416201A CA 2416201 A1 CA2416201 A1 CA 2416201A1
Authority
CA
Canada
Prior art keywords
implants
calcium phosphate
composite layers
electrochemically deposited
phosphate composite
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002416201A
Other languages
English (en)
Other versions
CA2416201C (fr
Inventor
Hans-Georg Neumann
Peter Zeggel
Petra Becker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DOT GmbH
Original Assignee
Dot Gmbh
Hans-Georg Neumann
Peter Zeggel
Petra Becker
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dot Gmbh, Hans-Georg Neumann, Peter Zeggel, Petra Becker filed Critical Dot Gmbh
Publication of CA2416201A1 publication Critical patent/CA2416201A1/fr
Application granted granted Critical
Publication of CA2416201C publication Critical patent/CA2416201C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/30—Inorganic materials
    • A61L27/32—Phosphorus-containing materials, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2002/3092—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth having an open-celled or open-pored structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00389—The prosthesis being coated or covered with a particular material
    • A61F2310/00592—Coating or prosthesis-covering structure made of ceramics or of ceramic-like compounds
    • A61F2310/00796—Coating or prosthesis-covering structure made of a phosphorus-containing compound, e.g. hydroxy(l)apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)

Abstract

L'invention concerne des couches composites de phosphate de calcium bioactives déposées électrochimiquement sur des implants osseux. De tels implants sont implantés sans ciment et se caractérisent par un pouvoir d'ostéointégration amélioré. Lesdites couches composites ultra-poreuses destinées à des implants sont composées d'au moins deux phases de phosphate de calcium de solubilités différentes. La structure ultra-poreuse de ces couches permet de simplifier l'immobilisation de cellules à partir desquelles le tissu osseux peut se régénérer. Les solubilités différentes des composantes de couches individuelles permettent d'obtenir la concentration locale d'ions calcium et d'ions phosphate accélérant le processus de guérison et s'adaptant au processus dans le temps.
CA002416201A 2000-07-17 2000-07-17 Couches composites de phosphate de calcium bioactives deposees electrochimiquement sur des implants Expired - Fee Related CA2416201C (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2000/006838 WO2002005862A1 (fr) 2000-07-17 2000-07-17 Couches composites de phosphate de calcium bioactives deposees electrochimiquement sur des implants

Publications (2)

Publication Number Publication Date
CA2416201A1 true CA2416201A1 (fr) 2003-01-15
CA2416201C CA2416201C (fr) 2008-11-18

Family

ID=8164028

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002416201A Expired - Fee Related CA2416201C (fr) 2000-07-17 2000-07-17 Couches composites de phosphate de calcium bioactives deposees electrochimiquement sur des implants

Country Status (6)

Country Link
EP (1) EP1301220A1 (fr)
JP (1) JP2004503333A (fr)
AU (2) AU2000259855B2 (fr)
CA (1) CA2416201C (fr)
HK (1) HK1060070A1 (fr)
WO (1) WO2002005862A1 (fr)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006007730A1 (fr) * 2004-07-21 2006-01-26 The University Of British Columbia Implants osseux et procedes d'enrobage de ces implants
US10004604B2 (en) 2006-09-08 2018-06-26 Kyocera Corporation Bioimplant for artifical joint with evanescent coating film
US10610614B2 (en) 2006-09-08 2020-04-07 Kyocera Corporation Bioimplant with evanescent coating film
US11278642B2 (en) 2006-09-08 2022-03-22 Takao Hotokebuchi Bioimplant with evanescent coating film
US11998659B2 (en) 2006-09-08 2024-06-04 Kyocera Corporation Bioimplant with evanescent coating film

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102012001260B4 (de) * 2012-01-23 2015-04-02 Dot Gmbh Antibakterielle und osteoinduktive Implantatbeschichtung

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5205921A (en) * 1991-02-04 1993-04-27 Queen's University At Kingston Method for depositing bioactive coatings on conductive substrates
DE19504386C2 (de) * 1995-02-10 1997-08-28 Univ Dresden Tech Verfahren zur Herstellung einer gradierten Beschichtung aus Calciumphosphatphasen und Metalloxidphasen auf metallischen Implantaten
EP0806212B1 (fr) * 1996-05-10 2003-04-02 IsoTis N.V. Dispositif pour l'incorporation et la délivrance d'agents bioactifs
US6045683A (en) * 1997-12-01 2000-04-04 University Of Alabama In Huntsville Modified brushite surface coating, process therefor, and low temperature conversion to hydroxyapatite
AU766735B2 (en) * 1998-09-15 2003-10-23 Isotis N.V. Osteoinduction

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006007730A1 (fr) * 2004-07-21 2006-01-26 The University Of British Columbia Implants osseux et procedes d'enrobage de ces implants
US10004604B2 (en) 2006-09-08 2018-06-26 Kyocera Corporation Bioimplant for artifical joint with evanescent coating film
US10610614B2 (en) 2006-09-08 2020-04-07 Kyocera Corporation Bioimplant with evanescent coating film
US11278642B2 (en) 2006-09-08 2022-03-22 Takao Hotokebuchi Bioimplant with evanescent coating film
US11998659B2 (en) 2006-09-08 2024-06-04 Kyocera Corporation Bioimplant with evanescent coating film

Also Published As

Publication number Publication date
WO2002005862A1 (fr) 2002-01-24
CA2416201C (fr) 2008-11-18
AU5985500A (en) 2002-01-30
WO2002005862A8 (fr) 2002-05-30
EP1301220A1 (fr) 2003-04-16
AU2000259855B2 (en) 2006-02-02
HK1060070A1 (en) 2004-07-30
AU2000259855A1 (en) 2002-05-02
JP2004503333A (ja) 2004-02-05

Similar Documents

Publication Publication Date Title
ATE415983T1 (de) Orthopädische prothese mit verbundbeschichtung
WO1994007432A3 (fr) Implants vasculaires poreux
EP0815806A3 (fr) Implant endovasculaire à porosité contrÔlée
ATE292986T1 (de) Verfahren zur knorpelgeweberegeneration
DE60039871D1 (de) Körper zum erzeugen von knochenwachstum und/oder bindegewebe und verfahren zur herstellung solches körpers
WO2006004686A3 (fr) Appareil muni d'un revetement bioceramique et procede de fabrication de l'appareil
WO2005114323A3 (fr) Procede de fabrication, du type impression 3d, avec liaison de materiau hydrosoluble puis amolissement et ecoulement et formation de films de materiau organique soluble en solvant
CA2286655A1 (fr) Decellularisation d'un tissu
EP0393788A3 (fr) Prothèse vasculaire et procédé de production pour prothèse vasculaire
DE60202461D1 (de) Kalziumphosphat / -sulfat-basierte knochenimplantat zusammensetzung
WO2002034116A3 (fr) Procedes et dispositifs de fusion de vertebres
WO2002070029A3 (fr) Granules de phosphate tricalcium-beta poreuses et procedes de fabrication correspondant
ATE493492T1 (de) Verfahren und system zur herstellung von stammzellen aus fettgewebe
WO2005053764A8 (fr) Implant et procede de production de celui-ci, et systeme d'implantation
WO1999016416A3 (fr) Implants medicaux revetus, leur procede de preparation et leur utilisation pour la prevention de restenoses
DE502006007273D1 (de) Spongiös-metallisches implantat und verfahren zu seiner herstellung
WO2005074530A3 (fr) Implant osseux metallique possedant une capacite d'implantation amelioree et procede de fabrication de celui-ci
IL174488A0 (en) Bioartificial implant and its use and method of reducing the risk for formation of connective tissue after implantation
WO2002041930A8 (fr) Elements de remplacement pour des tissus conjonctifs, procede de preparation et utilisations de ces derniers
CA2416201A1 (fr) Couches composites de phosphate de calcium bioactives deposees electrochimiquement sur des implants
JPH01151461A (ja) 生体用補綴材料
DE3779452D1 (de) Calciumphosphathaltiger, biokompatibler schichtkoerper und verfahren zu seiner herstellung.
KR101419779B1 (ko) 골 이식재 제조방법 및 이에 의해 제조된 골 이식재
JP2004503333A5 (fr)
Kaplan Open cell tantalum structures for cancellous bone implants and cell and tissue receptors

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed