CA2415849A1 - Pharmaceutical powder cartridge, and inhaler equipped with same - Google Patents

Pharmaceutical powder cartridge, and inhaler equipped with same Download PDF

Info

Publication number
CA2415849A1
CA2415849A1 CA002415849A CA2415849A CA2415849A1 CA 2415849 A1 CA2415849 A1 CA 2415849A1 CA 002415849 A CA002415849 A CA 002415849A CA 2415849 A CA2415849 A CA 2415849A CA 2415849 A1 CA2415849 A1 CA 2415849A1
Authority
CA
Canada
Prior art keywords
pharmaceutical powder
metering slide
metering
pharmaceutical
same
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002415849A
Other languages
French (fr)
Other versions
CA2415849C (en
Inventor
Joachim Goede
Karl-Heinz Lange
Martin Herder
Meike Irngartinger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Almirall SA
Original Assignee
Sofotec GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sofotec GmbH filed Critical Sofotec GmbH
Publication of CA2415849A1 publication Critical patent/CA2415849A1/en
Application granted granted Critical
Publication of CA2415849C publication Critical patent/CA2415849C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0003—Details of inhalators; Constructional features thereof with means for dispensing more than one drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/007—Mechanical counters
    • A61M15/0071—Mechanical counters having a display or indicator
    • A61M15/0073—Mechanical counters having a display or indicator on a ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicinal Preparation (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Basic Packing Technique (AREA)
  • Materials For Medical Uses (AREA)
  • External Artificial Organs (AREA)

Abstract

To improve administration of powdered pharmaceuticals, a pharmaceutical powder cartridge (1) for powder inhalers for holding a pharmaceutical depot for a large number of pharmaceutical powder doses is proposed, having at least one storage space (6) and an integrated metering device, said integrated metering device comprising at least one metering slide (9, 13, 14) which can be moved approximately transversely in a metering slide channel (12) at least from a filling position to an emptying position, approximately transversely with respect to the direction of flow of the pharmaceutical powder out from the at least one storage space (6), said metering slide channel (12) with the at least one metering slide (9, 13, 14) being sealed off from the environment at least in the filling position of the metering slide (9, 13, 14), and also further measures and a corresponding inhaler.
CA002415849A 2002-01-24 2003-01-08 Pharmaceutical powder cartridge, and inhaler equipped with same Expired - Fee Related CA2415849C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10202940.07 2002-01-24
DE10202940A DE10202940A1 (en) 2002-01-24 2002-01-24 Cartridge for a powder inhaler

Publications (2)

Publication Number Publication Date
CA2415849A1 true CA2415849A1 (en) 2003-07-24
CA2415849C CA2415849C (en) 2008-03-18

Family

ID=7713081

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002415849A Expired - Fee Related CA2415849C (en) 2002-01-24 2003-01-08 Pharmaceutical powder cartridge, and inhaler equipped with same

Country Status (23)

Country Link
EP (2) EP2286860A1 (en)
JP (1) JP4597523B2 (en)
KR (2) KR20110009727A (en)
CN (1) CN100584402C (en)
AR (1) AR038313A1 (en)
AT (1) ATE509652T1 (en)
AU (1) AU2003236784B2 (en)
BR (1) BR0307094A (en)
CA (1) CA2415849C (en)
DE (1) DE10202940A1 (en)
ES (1) ES2366683T3 (en)
HK (1) HK1078809A1 (en)
HR (1) HRP20040762A2 (en)
IL (1) IL162996A (en)
MX (1) MXPA04007197A (en)
NO (1) NO20043324L (en)
NZ (1) NZ534206A (en)
PL (1) PL204871B1 (en)
RU (1) RU2319512C2 (en)
TW (1) TW575441B (en)
UA (1) UA78746C2 (en)
WO (1) WO2003061742A2 (en)
ZA (1) ZA200405869B (en)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2165768B1 (en) 1999-07-14 2003-04-01 Almirall Prodesfarma Sa NEW DERIVATIVES OF QUINUCLIDINE AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM.
BRPI0417097A (en) * 2003-12-03 2007-03-13 Microdrug Ag pre-metered dry powder inhaler for moisture sensitive medicines
ES2265276B1 (en) 2005-05-20 2008-02-01 Laboratorios Almirall S.A. DERIVATIVES OF 4- (2-AMINO-1-HYDROXYETHYL) Phenol as agonists of the BETA2 ADRENERGIC RECEIVER.
DE102005046645B3 (en) * 2005-09-29 2006-07-20 Braunform Gmbh Medical powder inhaler has at least two reservoir containers from which different powders can be separately forwarded into a metering unit so that they are mixed together when traveling along an inhalation tube
ES2319596B1 (en) 2006-12-22 2010-02-08 Laboratorios Almirall S.A. NEW DERIVATIVES OF THE AMINO-NICOTINIC AND AMINO-ISONICOTINIC ACIDS.
MX2009006787A (en) 2006-12-22 2009-07-10 Almirall Lab Inhalation device for drugs in powder form.
ES2320955B1 (en) 2007-03-02 2010-03-16 Laboratorios Almirall S.A. NEW DERIVATIVES OF 3 - ((1,2,4) TRIAZOLO (4,3-A) PIRIDIN-7-IL) BENZAMIDA.
UY31272A1 (en) 2007-08-10 2009-01-30 Almirall Lab NEW DERIVATIVES OF AZABIFENILAMINOBENZOIC ACID
CA2716124A1 (en) * 2008-02-20 2009-08-27 Boehringer Ingelheim International Gmbh Powder inhalers
EP2100598A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2100599A1 (en) 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2108641A1 (en) 2008-04-11 2009-10-14 Laboratorios Almirall, S.A. New substituted spiro[cycloalkyl-1,3'-indo]-2'(1'H)-one derivatives and their use as p38 mitogen-activated kinase inhibitors
EP2113503A1 (en) 2008-04-28 2009-11-04 Laboratorios Almirall, S.A. New substituted indolin-2-one derivatives and their use as p39 mitogen-activated kinase inhibitors
EP2135610A1 (en) 2008-06-20 2009-12-23 Laboratorios Almirall, S.A. Combination comprising DHODH inhibitors and methotrexate
EP2177521A1 (en) 2008-10-14 2010-04-21 Almirall, S.A. New 2-Amidothiadiazole Derivatives
EP2196465A1 (en) 2008-12-15 2010-06-16 Almirall, S.A. (3-oxo)pyridazin-4-ylurea derivatives as PDE4 inhibitors
UY32297A (en) 2008-12-22 2010-05-31 Almirall Sa MESILATE SALT OF 5- (2 - {[6- (2,2-DIFLUORO-2-PHENYLITOXI) HEXIL] AMINO} -1-HYDROXYETHYL) -8-HYDROXYCHINOLIN-2 (1H) -ONA AS A RECEIVER AGONIST B (BETA ) 2 ACRENERGIC
EP2202232A1 (en) 2008-12-26 2010-06-30 Laboratorios Almirall, S.A. 1,2,4-oxadiazole derivatives and their therapeutic use
EP2210890A1 (en) 2009-01-19 2010-07-28 Almirall, S.A. Oxadiazole derivatives as S1P1 receptor agonists
EP2210615A1 (en) 2009-01-21 2010-07-28 Almirall, S.A. Combinations comprising methotrexate and DHODH inhibitors
EP2221055A1 (en) 2009-02-18 2010-08-25 Almirall, S.A. 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one for the treatment of lung function
EP2221297A1 (en) 2009-02-18 2010-08-25 Almirall, S.A. 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one and its use in the treatment of pulmonary diseases
EP2226323A1 (en) 2009-02-27 2010-09-08 Almirall, S.A. New tetrahydropyrazolo[3,4-c]isoquinolin-5-amine derivatives
EP2228368A1 (en) 2009-03-12 2010-09-15 Almirall, S.A. Process for manufacturing 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one
EP2239256A1 (en) 2009-03-13 2010-10-13 Almirall, S.A. Sodium salt of 5-cyclopropyl-2-{[2-(2,6-difluorophenyl)pyrimidin-5-yl]amino}benzoic acid as DHODH inhibitor
US8815258B2 (en) 2009-05-29 2014-08-26 Pearl Therapeutics, Inc. Compositions, methods and systems for respiratory delivery of two or more active agents
RU2580315C3 (en) 2009-05-29 2021-06-18 Перл Терапьютикс, Инк. COMPOSITIONS FOR RESPIRATORY DELIVERY OF ACTIVE SUBSTANCES AND RELATED METHODS AND SYSTEMS
EP2305660A1 (en) 2009-09-25 2011-04-06 Almirall, S.A. New thiadiazole derivatives
EP2314577A1 (en) 2009-10-16 2011-04-27 Almirall, S.A. Process for manufacturing 2-[(3,5-difluoro-3'-methoxy-1,1'-biphenyl-4-yl)amino]nicotinic acid
EP2322176A1 (en) 2009-11-11 2011-05-18 Almirall, S.A. New 7-phenyl-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one derivatives
EP2343287A1 (en) 2009-12-10 2011-07-13 Almirall, S.A. New 2-aminothiadiazole derivatives
EP2338888A1 (en) 2009-12-24 2011-06-29 Almirall, S.A. Imidazopyridine derivatives as JAK inhibitors
EP2360158A1 (en) 2010-02-18 2011-08-24 Almirall, S.A. Pyrazole derivatives as jak inhibitors
EP2366702A1 (en) 2010-03-18 2011-09-21 Almirall, S.A. New oxadiazole derivatives
EP2380890A1 (en) 2010-04-23 2011-10-26 Almirall, S.A. New 7,8-dihydro-1,6-naphthyridin-5(6h)-one-derivatives as PDE4 inhibitors
EP2386555A1 (en) 2010-05-13 2011-11-16 Almirall, S.A. New cyclohexylamine derivatives having beta2 adrenergic agonist and m3 muscarinic antagonist activities
EP2390252A1 (en) 2010-05-19 2011-11-30 Almirall, S.A. New pyrazole derivatives
EP2394998A1 (en) 2010-05-31 2011-12-14 Almirall, S.A. 3-(5-Amino-6-oxo-1,6-dihydropyridazin-3-yl)-biphenyl derivatives as PDE4 inhibitors
EP2397482A1 (en) 2010-06-15 2011-12-21 Almirall, S.A. Heteroaryl imidazolone derivatives as jak inhibitors
EP2441755A1 (en) 2010-09-30 2012-04-18 Almirall, S.A. Pyridine- and isoquinoline-derivatives as Syk and JAK kinase inhibitors
EP2510928A1 (en) 2011-04-15 2012-10-17 Almirall, S.A. Aclidinium for use in improving the quality of sleep in respiratory patients
EP2578570A1 (en) 2011-10-07 2013-04-10 Almirall, S.A. Novel process for preparing 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1(r)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one via novel intermediates of synthesis.
EP2641900A1 (en) 2012-03-20 2013-09-25 Almirall, S.A. Novel polymorphic Crystal forms of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-(R)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one, heminapadisylate as agonist of the ß2 adrenergic receptor.
EP2647627A1 (en) 2012-04-02 2013-10-09 Almirall, S.A. Salts of 5-[(1r)-2-({2-[4-(2,2-difluoro-2-phenylethoxy)phenyl] ethyl}amino)-1-hydroxyethyl]-8-hydroxyquinolin-2(1h)-one.
EP2666465A1 (en) 2012-05-25 2013-11-27 Almirall, S.A. Novel dosage and formulation
MX354384B (en) * 2012-11-12 2018-03-02 Sanofi Sa Assembly for an inhalation device and use of a sealing member.
SG11201507286QA (en) 2013-03-15 2015-10-29 Pearl Therapeutics Inc Methods and systems for conditioning of particulate crystalline materials
WO2019191628A1 (en) * 2018-03-30 2019-10-03 Mariani Nick Inhaler and method

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE483136A (en) 1947-09-04 1942-06-30
US2587215A (en) * 1949-04-27 1952-02-26 Frank P Priestly Inhalator
US4274403A (en) 1979-08-29 1981-06-23 Struve Roger L Inhaler
FI69963C (en) 1984-10-04 1986-09-12 Orion Yhtymae Oy DOSERINGSANORDNING
ATE92762T1 (en) 1989-09-08 1993-08-15 Glaxo Group Ltd MEDICATION.
IL95590A (en) 1989-09-08 1996-06-18 Glaxo Group Ltd Pharmaceutical compositions comprising salmeterol and fluticasone propionate
DE4004904A1 (en) 1990-02-16 1990-09-13 Gerhard Brendel DRUM APPLICATOR
ATE164525T1 (en) 1990-09-26 1998-04-15 Pharmachemie Bv INHALER WITH A RESERVOIR FOR SEVERAL DOSED INHALATION AGENTS, WITH TRANSPORT DEVICE AND WITH VOLTAGE CHAMBER
GB9026025D0 (en) 1990-11-29 1991-01-16 Boehringer Ingelheim Kg Inhalation device
DE4211475A1 (en) 1991-12-14 1993-06-17 Asta Medica Ag POWDER INHALATOR
CZ288032B6 (en) 1991-12-18 2001-04-11 Aktiebolaget Astra Pharmaceutical preparation intended for administration by inhalation
GB9203761D0 (en) 1992-02-21 1992-04-08 Innovata Biomed Ltd Inhaler
DE4239402A1 (en) 1992-11-24 1994-05-26 Bayer Ag Multiple dosage powder inhaler - has acceleration channel and dwell chamber for uniformly high drug dispersion
RU2111020C1 (en) * 1992-12-18 1998-05-20 Шеринг Корпорейшн Powdered drug inhaler
DE4340768A1 (en) 1993-11-30 1995-06-01 Bayer Ag Inhalation device
DE4400084C2 (en) 1994-01-04 2001-08-02 Softec Gmbh & Co Kg Device for administering medication in solid form finely distributed in an air stream
DE4400083C2 (en) 1994-01-04 1997-07-03 Asta Medica Ag Packaging for small pre-dosed quantities of a finely divided solid
FI942196A (en) 1994-05-11 1995-11-12 Orion Yhtymae Oy powder inhaler
FI95441C (en) 1994-05-31 1996-02-12 Leiras Oy Inhaler drug chamber
DE19522415C2 (en) * 1995-06-21 2003-12-04 Sofotec Gmbh & Co Kg Drug powder cartridge with integrated dosing device and powder inhaler with means for actuating the dosing device of the drug powder cartridge
IL122494A (en) 1995-06-21 2001-08-08 Asta Medica Ag Pharmaceutical powder cartridge with integrated metering device and inhaler for powdered medicaments
DE19522416C2 (en) 1995-06-21 2003-11-20 Sofotec Gmbh & Co Kg Device for dispersing powder in an air stream for use with powder inhalers
DE19523516C1 (en) 1995-06-30 1996-10-31 Asta Medica Ag Inhaler for administering medication from blister packs
JPH09301400A (en) * 1996-05-15 1997-11-25 Hiroshi Mitsumori Cap
EP1183061B2 (en) 1999-06-05 2012-10-17 Innovata Biomed Limited Medicament delivery system
AU7290800A (en) 1999-09-17 2001-04-24 Orion Corporation Moisture protected powder inhaler
AU5286201A (en) * 1999-11-22 2001-07-03 Capitol Specialty Plastics, Inc. Heat molded insert consisting of an ethylene-vinyl acetate/desiccant blend
AR026914A1 (en) * 1999-12-11 2003-03-05 Glaxo Group Ltd MEDICINAL DISTRIBUTOR
GB9929486D0 (en) * 1999-12-15 2000-02-09 Glaxo Group Ltd Inhalation delivery apparatus and method
DE19961300A1 (en) * 1999-12-18 2001-06-21 Asta Medica Ag Storage system for medicinal products in powder form and inhaler equipped with them
GB0031176D0 (en) * 2000-12-21 2001-01-31 Glaxo Group Ltd Medicament dispenser

Also Published As

Publication number Publication date
ATE509652T1 (en) 2011-06-15
WO2003061742A3 (en) 2003-12-31
CN1642591A (en) 2005-07-20
DE10202940A1 (en) 2003-07-31
CN100584402C (en) 2010-01-27
ES2366683T3 (en) 2011-10-24
TW200302116A (en) 2003-08-01
WO2003061742A2 (en) 2003-07-31
EP1469900B1 (en) 2011-05-18
NO20043324L (en) 2004-08-10
KR20110009727A (en) 2011-01-28
BR0307094A (en) 2005-03-01
EP2286860A1 (en) 2011-02-23
UA78746C2 (en) 2007-04-25
AU2003236784B2 (en) 2008-01-24
PL374327A1 (en) 2005-10-17
NZ534206A (en) 2007-03-30
IL162996A (en) 2011-06-30
HRP20040762A2 (en) 2004-10-31
JP2005515038A (en) 2005-05-26
HK1078809A1 (en) 2006-03-24
MXPA04007197A (en) 2005-07-05
ZA200405869B (en) 2006-06-28
KR20040096534A (en) 2004-11-16
WO2003061742A8 (en) 2004-10-21
JP4597523B2 (en) 2010-12-15
AR038313A1 (en) 2005-01-12
TW575441B (en) 2004-02-11
CA2415849C (en) 2008-03-18
EP1469900A2 (en) 2004-10-27
RU2004126087A (en) 2005-03-20
PL204871B1 (en) 2010-02-26
RU2319512C2 (en) 2008-03-20

Similar Documents

Publication Publication Date Title
CA2415849A1 (en) Pharmaceutical powder cartridge, and inhaler equipped with same
CA2225396A1 (en) Pharmaceutical powder cartridge with integrated metering device and inhaler for powdered medicaments
CA2578812A1 (en) Powder inhaler
AU2410295A (en) Powder inhaler
EP1322356B1 (en) Device for delivering physiologically active agent in powdered form
WO2004026380A3 (en) Inhaler
US20050155601A1 (en) Sublingual drug delivery device
AU2003212518A1 (en) Medicament delivery and packaging
SG134169A1 (en) Powder inhalator
MX2008011620A (en) Inhalator for powdery substances.
KR20050048687A (en) Medicament inhaler
AU2001270751A1 (en) Valve for aerosol container
DE60120401D1 (en) MULTIPLE DOSE DISPENSER FOR THE ADMINISTRATION OF A POWDERY MEDICAMENT
AU2001276538A1 (en) Device for delivering physiologically active agent in powdered form
WO2001068017A3 (en) Improvements for the storage and delivery of multi-dose, preservative-free pharmaceuticals
WO2005023330A3 (en) Pharmaceutical metered dose inhaler and methods relating thereto
CA2369700A1 (en) Powder inhaler
MY135868A (en) Inhaler cap strap
CA2235005A1 (en) Powder inhaler
AU2002240978A1 (en) Powder inhaler
SE9903824D0 (en) Device for dispensing multiple doses for powder inhalers and the corresponding dispensing procedure

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20130108