CA2401388C - Dispositif servant a mesurer un volume de medicament - Google Patents

Dispositif servant a mesurer un volume de medicament Download PDF

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Publication number
CA2401388C
CA2401388C CA002401388A CA2401388A CA2401388C CA 2401388 C CA2401388 C CA 2401388C CA 002401388 A CA002401388 A CA 002401388A CA 2401388 A CA2401388 A CA 2401388A CA 2401388 C CA2401388 C CA 2401388C
Authority
CA
Canada
Prior art keywords
drug
chamber
piston
vial
volume
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002401388A
Other languages
English (en)
Other versions
CA2401388A1 (fr
Inventor
Gilad Lavi
Gil Yigal
Izrail Tsals
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Elan Pharma International Ltd
Original Assignee
Elan Pharma International Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elan Pharma International Ltd filed Critical Elan Pharma International Ltd
Publication of CA2401388A1 publication Critical patent/CA2401388A1/fr
Application granted granted Critical
Publication of CA2401388C publication Critical patent/CA2401388C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/19—Syringes having more than one chamber, e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/21—General characteristics of the apparatus insensitive to tilting or inclination, e.g. spill-over prevention
    • A61M2205/215—Tilt detection, e.g. for warning or shut-off
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/1782—Devices aiding filling of syringes in situ
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M5/2422—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule
    • A61M5/2425—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule by compression of deformable ampoule or carpule wall
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M5/2448—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic comprising means for injection of two or more media, e.g. by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • A61M5/31553—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe without axial movement of dose setting member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533—Dosing mechanisms, i.e. setting a dose
    • A61M5/31545—Setting modes for dosing
    • A61M5/31548—Mechanically operated dose setting member
    • A61M5/31561—Mechanically operated dose setting member using freely adjustable volume steps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
    • A61M5/31586—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by rotationally moving or pivoted actuator, e.g. an injection lever or handle

Abstract

L'invention concerne des dispositifs et des procédés destinés à des systèmes d'administration de médicament. Ces procédés comprennent les étapes consistant à : premièrement prélever et mesurer un volume prédéterminé de médicament liquide à partir d'un contenant (933) de médicament liquide dans une chambre (950) de mesure de volume ; et deuxièmement chasser le volume prédéterminé vers l'élément d'administration tel qu'une aiguille d'injection. La chambre (950) de mesure de volume peut fonctionner à la manière d'un ensemble piston et cylindre, dans lequel un contact fileté entre un bouton (966) de commande et une tige (934) de piston filetée permet de retirer progressivement le piston dans une mesure prédéterminée, ce qui permet de déterminer le volume de médicament. Une pression sur le même bouton (966) de commande entraîne un dégagement des filetages et une poussée du piston (952) vers l'avant produite par un ressort (960) pour chasser le volume prédéterminé de médicament à travers l'élément d'administration (p. ex. aiguille).
CA002401388A 2000-03-28 2001-03-28 Dispositif servant a mesurer un volume de medicament Expired - Fee Related CA2401388C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19274300P 2000-03-28 2000-03-28
US60/192,743 2000-03-28
PCT/GB2001/001374 WO2001072354A2 (fr) 2000-03-28 2001-03-28 Dispositif servant a mesurer un volume de medicament

Publications (2)

Publication Number Publication Date
CA2401388A1 CA2401388A1 (fr) 2001-10-04
CA2401388C true CA2401388C (fr) 2009-09-08

Family

ID=22710877

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002401388A Expired - Fee Related CA2401388C (fr) 2000-03-28 2001-03-28 Dispositif servant a mesurer un volume de medicament

Country Status (5)

Country Link
EP (1) EP1267961A2 (fr)
JP (1) JP2003527933A (fr)
AU (1) AU2001242610A1 (fr)
CA (1) CA2401388C (fr)
WO (1) WO2001072354A2 (fr)

Families Citing this family (53)

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US6719719B2 (en) * 1998-11-13 2004-04-13 Elan Pharma International Limited Spike for liquid transfer device, liquid transfer device including spike, and method of transferring liquids using the same
US7252651B2 (en) 2003-01-07 2007-08-07 Becton, Dickinson And Company Disposable injection device
EP2412359A1 (fr) * 2006-09-29 2012-02-01 Infa S.A. Système d'emballage pour compositions pharmaceutiques et kit d'administration intraveineuse
EP1992374A1 (fr) 2007-05-16 2008-11-19 Boehringer Ingelheim Pharma GmbH & Co. KG Dispositif distributeur
EP1992380A1 (fr) 2007-05-16 2008-11-19 Boehringer Ingelheim Pharma GmbH & Co. KG Dispositif distributeur
EP1992372A1 (fr) 2007-05-16 2008-11-19 Boehringer Ingelheim Pharma GmbH & Co. KG Dispositif de distribution
EP1992377A1 (fr) 2007-05-16 2008-11-19 Boehringer Ingelheim Pharma GmbH & Co. KG Dispositif distributeur
EP1992376A1 (fr) 2007-05-16 2008-11-19 Boehringer Ingelheim Pharma GmbH & Co. KG Dispositif distributeur
EP1992379A1 (fr) * 2007-05-16 2008-11-19 Boehringer Ingelheim Pharma GmbH & Co. KG Dispositif distributeur
EP1992373A1 (fr) 2007-05-16 2008-11-19 Boehringer Ingelheim Pharma GmbH & Co. KG Dispositif distributeur
US7959598B2 (en) 2008-08-20 2011-06-14 Asante Solutions, Inc. Infusion pump systems and methods
US8118777B2 (en) * 2009-05-29 2012-02-21 Cook Medical Technologies Llc Systems and methods for delivering therapeutic agents
JP2012528692A (ja) * 2009-06-02 2012-11-15 ユーコン・メディカル，リミテッド・ライアビリティ・カンパニー 多容器移送・送達装置
CA2797795A1 (fr) 2010-04-29 2011-11-10 Yukon Medical, Llc Dispositif de distribution et de transfert de fluide dans plusieurs recipients
DK2646077T3 (en) * 2010-11-29 2015-09-28 Sanofi Aventis Deutschland DISPENSE INTERFACE COMPONENT FOR A MEDICINE DELIVERY DEVICE
EP3549524B1 (fr) 2012-03-30 2023-01-25 Insulet Corporation Dispositif d'administration de fluide avec outil d'accès transcutané, mécanisme d'insertion et contrôle de glycémie destine à être utilisé avec le dispositif
HUE059908T2 (hu) * 2013-06-18 2023-01-28 Enable Injections Inc Fiolaátviteli és injektáló készülék és eljárás
GB2523989B (en) 2014-01-30 2020-07-29 Insulet Netherlands B V Therapeutic product delivery system and method of pairing
JP6413780B2 (ja) * 2015-01-19 2018-10-31 株式会社島津製作所 カラムとニードルの相互接続機構
CN111905188B (zh) 2015-02-18 2022-07-22 英赛罗公司 流体输送和输注装置及其使用方法
CN107580489B (zh) 2015-03-26 2020-10-16 因内博注射剂公司 加压气体驱动的药剂转移和再悬浮设备和方法
WO2017091584A1 (fr) 2015-11-25 2017-06-01 Insulet Corporation Dispositif portable de distribution de médicament
EP3389592A1 (fr) * 2015-12-14 2018-10-24 H. Hoffnabb-La Roche Ag Dispositif d'administration médical
EP3374905A1 (fr) 2016-01-13 2018-09-19 Bigfoot Biomedical, Inc. Interface utilisateur pour système de gestion du diabète
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TWI746569B (zh) 2016-06-08 2021-11-21 瑞士商瑞健醫療股份有限公司 計量器具、注射裝置、及其應用
US10765807B2 (en) 2016-09-23 2020-09-08 Insulet Corporation Fluid delivery device with sensor
WO2018096149A1 (fr) 2016-11-28 2018-05-31 Idorsia Pharmaceuticals Ltd Dispositif de distribution d'une substance
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CN111132649A (zh) * 2017-07-20 2020-05-08 詹森生物科技公司 药物混合装置
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Also Published As

Publication number Publication date
CA2401388A1 (fr) 2001-10-04
AU2001242610A1 (en) 2001-10-08
WO2001072354A3 (fr) 2001-12-20
JP2003527933A (ja) 2003-09-24
WO2001072354A2 (fr) 2001-10-04
EP1267961A2 (fr) 2003-01-02

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