CA2395811A1 - Acides nucleiques, proteines, et anticorps - Google Patents

Acides nucleiques, proteines, et anticorps Download PDF

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Publication number
CA2395811A1
CA2395811A1 CA002395811A CA2395811A CA2395811A1 CA 2395811 A1 CA2395811 A1 CA 2395811A1 CA 002395811 A CA002395811 A CA 002395811A CA 2395811 A CA2395811 A CA 2395811A CA 2395811 A1 CA2395811 A1 CA 2395811A1
Authority
CA
Canada
Prior art keywords
polypeptide
seq
sequence
polypeptides
polynucleotide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CA002395811A
Other languages
English (en)
Inventor
Craig A. Rosen
Steven C. Barash
Steven M. Ruben
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Human Genome Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Human Genome Sciences Inc filed Critical Human Genome Sciences Inc
Publication of CA2395811A1 publication Critical patent/CA2395811A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4723—Cationic antimicrobial peptides, e.g. defensins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

La présente invention concerne de nouvelles protéines, notamment des molécules d'acide nucléique isolées codant de nouveaux polypeptides. Elle concerne de nouveaux polypeptides, et des anticorps qui se lient à ces polypeptides. L'invention concerne également des vecteurs, des cellules hôtes, et des méthodes recombinantes et synthétiques de production de polynucléotides et/ou de polypeptides humains et des anticorps. Elle concerne des méthodes diagnostiques et thérapeutiques servant à diagnostiquer, traiter, prévenir et/ou pronostiquer des troubles liés à ces nouveaux polypeptides. Elle concerne en outre des méthodes de criblage permettant d'identifier des agonistes et des antagonistes des polynucléotides et polypeptides de l'invention. L'invention concerne enfin des méthodes et/ou des compositions pouvant inhiber ou améliorer la production et la fonction des polypeptides de l'invention.
CA002395811A 2000-01-31 2001-01-17 Acides nucleiques, proteines, et anticorps Withdrawn CA2395811A1 (fr)

Applications Claiming Priority (235)

Application Number Priority Date Filing Date Title
US17906500P 2000-01-31 2000-01-31
US60/179,065 2000-01-31
US18062800P 2000-02-04 2000-02-04
US60/180,628 2000-02-04
US18466400P 2000-02-24 2000-02-24
US60/184,664 2000-02-24
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US18987400P 2000-03-16 2000-03-16
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US19007600P 2000-03-17 2000-03-17
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US19812300P 2000-04-18 2000-04-18
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US20551500P 2000-05-19 2000-05-19
US60/205,515 2000-05-19
US20946700P 2000-06-07 2000-06-07
US60/209,467 2000-06-07
US21488600P 2000-06-28 2000-06-28
US60/214,886 2000-06-28
US21513500P 2000-06-30 2000-06-30
US60/215,135 2000-06-30
US21664700P 2000-07-07 2000-07-07
US21688000P 2000-07-07 2000-07-07
US60/216,647 2000-07-07
US60/216,880 2000-07-07
US21749600P 2000-07-11 2000-07-11
US21748700P 2000-07-11 2000-07-11
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US21829000P 2000-07-14 2000-07-14
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US22096400P 2000-07-26 2000-07-26
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US60/220,963 2000-07-26
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US22544700P 2000-08-14 2000-08-14
US22575800P 2000-08-14 2000-08-14
US22526700P 2000-08-14 2000-08-14
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US60/224,518 2000-08-14
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US60/225,270 2000-08-14
US60/224,519 2000-08-14
US60/225,267 2000-08-14
US60/225,266 2000-08-14
US60/225,757 2000-08-14
US60/225,447 2000-08-14
US60/225,758 2000-08-14
US60/225,759 2000-08-14
US60/225,213 2000-08-14
US22627900P 2000-08-18 2000-08-18
US60/226,279 2000-08-18
US22686800P 2000-08-22 2000-08-22
US22668100P 2000-08-22 2000-08-22
US22718200P 2000-08-22 2000-08-22
US60/227,182 2000-08-22
US60/226,868 2000-08-22
US60/226,681 2000-08-22
US22700900P 2000-08-23 2000-08-23
US60/227,009 2000-08-23
US22892400P 2000-08-30 2000-08-30
US60/228,924 2000-08-30
US22928700P 2000-09-01 2000-09-01
US22934500P 2000-09-01 2000-09-01
US22934300P 2000-09-01 2000-09-01
US22934400P 2000-09-01 2000-09-01
US60/229,343 2000-09-01
US60/229,344 2000-09-01
US60/229,345 2000-09-01
US60/229,287 2000-09-01
US22950900P 2000-09-05 2000-09-05
US22951300P 2000-09-05 2000-09-05
US60/229,513 2000-09-05
US60/229,509 2000-09-05
US23043800P 2000-09-06 2000-09-06
US23043700P 2000-09-06 2000-09-06
US60/230,437 2000-09-06
US60/230,438 2000-09-06
US23124400P 2000-09-08 2000-09-08
US23208000P 2000-09-08 2000-09-08
US23141300P 2000-09-08 2000-09-08
US23141400P 2000-09-08 2000-09-08
US23124300P 2000-09-08 2000-09-08
US23124200P 2000-09-08 2000-09-08
US23208100P 2000-09-08 2000-09-08
US60/231,414 2000-09-08
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US23196800P 2000-09-12 2000-09-12
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US23240000P 2000-09-14 2000-09-14
US23239800P 2000-09-14 2000-09-14
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US23240100P 2000-09-14 2000-09-14
US23306500P 2000-09-14 2000-09-14
US60/233,063 2000-09-14
US60/232,401 2000-09-14
US60/232,398 2000-09-14
US60/232,397 2000-09-14
US60/233,064 2000-09-14
US60/232,400 2000-09-14
US60/233,065 2000-09-14
US60/232,399 2000-09-14
US23422300P 2000-09-21 2000-09-21
US23427400P 2000-09-21 2000-09-21
US60/234,274 2000-09-21
US60/234,223 2000-09-21
US23499800P 2000-09-25 2000-09-25
US23499700P 2000-09-25 2000-09-25
US60/234,997 2000-09-25
US60/234,998 2000-09-25
US23548400P 2000-09-26 2000-09-26
US60/235,484 2000-09-26
US23583600P 2000-09-27 2000-09-27
US23583400P 2000-09-27 2000-09-27
US60/235,834 2000-09-27
US60/235,836 2000-09-27
US23637000P 2000-09-29 2000-09-29
US23636700P 2000-09-29 2000-09-29
US23636800P 2000-09-29 2000-09-29
US23636900P 2000-09-29 2000-09-29
US23632700P 2000-09-29 2000-09-29
US60/236,327 2000-09-29
US60/236,367 2000-09-29
US60/236,369 2000-09-29
US60/236,370 2000-09-29
US60/236,368 2000-09-29
US23703800P 2000-10-02 2000-10-02
US23703900P 2000-10-02 2000-10-02
US23704000P 2000-10-02 2000-10-02
US23703700P 2000-10-02 2000-10-02
US23680200P 2000-10-02 2000-10-02
US60/237,040 2000-10-02
US60/236,802 2000-10-02
US60/237,037 2000-10-02
US60/237,039 2000-10-02
US60/237,038 2000-10-02
US23993500P 2000-10-13 2000-10-13
US23993700P 2000-10-13 2000-10-13
US60/239,937 2000-10-13
US60/239,935 2000-10-13
US24096000P 2000-10-20 2000-10-20
US24178500P 2000-10-20 2000-10-20
US24178600P 2000-10-20 2000-10-20
US24180900P 2000-10-20 2000-10-20
US24182600P 2000-10-20 2000-10-20
US24180800P 2000-10-20 2000-10-20
US24178700P 2000-10-20 2000-10-20
US24122100P 2000-10-20 2000-10-20
US60/241,809 2000-10-20
US60/241,787 2000-10-20
US60/241,221 2000-10-20
US60/241,826 2000-10-20
US60/241,785 2000-10-20
US60/241,786 2000-10-20
US60/241,808 2000-10-20
US60/240,960 2000-10-20
US24461700P 2000-11-01 2000-11-01
US60/244,617 2000-11-01
US24652700P 2000-11-08 2000-11-08
US24652400P 2000-11-08 2000-11-08
US24652500P 2000-11-08 2000-11-08
US24653200P 2000-11-08 2000-11-08
US24652300P 2000-11-08 2000-11-08
US24647600P 2000-11-08 2000-11-08
US24647400P 2000-11-08 2000-11-08
US24647500P 2000-11-08 2000-11-08
US24647700P 2000-11-08 2000-11-08
US24652800P 2000-11-08 2000-11-08
US24652600P 2000-11-08 2000-11-08
US60/246,611 2000-11-08
US60/246,474 2000-11-08
US60/246,523 2000-11-08
US60/246,526 2000-11-08
US60/246,525 2000-11-08
US60/246,477 2000-11-08
US60/246,532 2000-11-08
US60/246,610 2000-11-08
US60/246,524 2000-11-08
US60/246,609 2000-11-08
US60/246,476 2000-11-08
US60/246,613 2000-11-08
US60/246,527 2000-11-08
US60/246,475 2000-11-08
US60/246,528 2000-11-08
US60/246,478 2000-11-08
US60/249,207 2000-11-17
US60/249,213 2000-11-17
US60/249,215 2000-11-17
US60/249,218 2000-11-17
US60/249,297 2000-11-17
US60/249,265 2000-11-17
US60/249,217 2000-11-17
US60/249,300 2000-11-17
US60/249,299 2000-11-17
US60/249,208 2000-11-17
US60/249,264 2000-11-17
US60/249,216 2000-11-17
US60/249,212 2000-11-17
US60/249,210 2000-11-17
US60/249,245 2000-11-17
US60/249,211 2000-11-17
US60/249,214 2000-11-17
US60/249,244 2000-11-17
US60/249,209 2000-11-17
US60/250,391 2000-12-01
US60/250,160 2000-12-01
US60/251,030 2000-12-05
US60/256,719 2000-12-05
US60/251,988 2000-12-05
US60/251,479 2000-12-06
US60/251,869 2000-12-08
US60/251,989 2000-12-08
US60/251,990 2000-12-08
US60/251,868 2000-12-08
US60/251,856 2000-12-08
US60/254,097 2000-12-11
US60/259,678 2001-01-05

Publications (1)

Publication Number Publication Date
CA2395811A1 true CA2395811A1 (fr) 2001-08-02

Family

ID=27587114

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002395811A Withdrawn CA2395811A1 (fr) 2000-01-31 2001-01-17 Acides nucleiques, proteines, et anticorps

Country Status (2)

Country Link
CA (1) CA2395811A1 (fr)
WO (1) WO2001055306A2 (fr)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2807552A1 (fr) 2010-08-06 2012-02-09 Moderna Therapeutics, Inc. Acides nucleiques modifies et leurs procedes d'utilisation
DK3590949T3 (da) 2010-10-01 2022-07-11 Modernatx Inc Ribonukleinsyrer indeholdende n1-methyl-pseudouracil og anvendelse heraf
CA2831613A1 (fr) 2011-03-31 2012-10-04 Moderna Therapeutics, Inc. Administration et formulation d'acides nucleiques genetiquement modifies
US9464124B2 (en) 2011-09-12 2016-10-11 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
SG10201602654SA (en) 2011-10-03 2016-05-30 Moderna Therapeutics Inc Modified nucleosides,nucleotides,and nucleic acids,and uses thereof
WO2013090648A1 (fr) 2011-12-16 2013-06-20 modeRNA Therapeutics Nucléoside, nucléotide, et compositions d'acide nucléique modifiés
US9283287B2 (en) 2012-04-02 2016-03-15 Moderna Therapeutics, Inc. Modified polynucleotides for the production of nuclear proteins
US10501513B2 (en) 2012-04-02 2019-12-10 Modernatx, Inc. Modified polynucleotides for the production of oncology-related proteins and peptides
US9572897B2 (en) 2012-04-02 2017-02-21 Modernatx, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
JP2015516143A (ja) 2012-04-02 2015-06-08 モデルナ セラピューティクス インコーポレイテッドＭｏｄｅｒｎａ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． ヒト疾患に関連するタンパク質の産生のための修飾ポリヌクレオチド
US9303079B2 (en) 2012-04-02 2016-04-05 Moderna Therapeutics, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
LT2922554T (lt) 2012-11-26 2022-06-27 Modernatx, Inc. Terminaliai modifikuota rnr
WO2014152031A1 (fr) 2013-03-15 2014-09-25 Moderna Therapeutics, Inc. Purification d'acide ribonucléique
US8980864B2 (en) 2013-03-15 2015-03-17 Moderna Therapeutics, Inc. Compositions and methods of altering cholesterol levels
US10077439B2 (en) 2013-03-15 2018-09-18 Modernatx, Inc. Removal of DNA fragments in mRNA production process
WO2014152027A1 (fr) 2013-03-15 2014-09-25 Moderna Therapeutics, Inc. Procédés de fabrication pour la production de transcrits d'arn
WO2014144767A1 (fr) 2013-03-15 2014-09-18 Moderna Therapeutics, Inc. Purification d'arnm par échange d'ions
RS62529B1 (sr) 2013-07-11 2021-11-30 Modernatx Inc Kompozicije koje sadrže sintetičke polinukleotide koji kodiraju proteine povezane sa crispr i sintetičke sgrnk i postupci upotrebe
WO2015048744A2 (fr) 2013-09-30 2015-04-02 Moderna Therapeutics, Inc. Polynucléotides codant des polypeptides de modulation immunitaire
EP3052511A4 (fr) 2013-10-02 2017-05-31 Moderna Therapeutics, Inc. Molécules de polynucléotides et leurs utilisations
AU2014329452B2 (en) 2013-10-03 2019-06-20 Moderna Therapeutics, Inc. Polynucleotides encoding low density lipoprotein receptor
EP3157573A4 (fr) 2014-06-19 2018-02-21 Moderna Therapeutics, Inc. Molécules d'acide nucléique alternatives et leurs utilisations
EP3169335B8 (fr) 2014-07-16 2019-10-09 ModernaTX, Inc. Polynucléotides circulaires
US11434486B2 (en) 2015-09-17 2022-09-06 Modernatx, Inc. Polynucleotides containing a morpholino linker
CN108438819B (zh) * 2018-04-19 2024-03-26 海盐明盛塑业有限公司 一种塑料瓶定位输送封口装置

Also Published As

Publication number Publication date
WO2001055306A2 (fr) 2001-08-02
WO2001055306A8 (fr) 2001-09-07
WO2001055306A3 (fr) 2001-12-20

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AZWI Withdrawn application
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Effective date: 20021120

AZWI Withdrawn application

Effective date: 20021120