CA2392090A1 - G-protein coupled receptor - Google Patents

G-protein coupled receptor Download PDF

Info

Publication number
CA2392090A1
CA2392090A1 CA002392090A CA2392090A CA2392090A1 CA 2392090 A1 CA2392090 A1 CA 2392090A1 CA 002392090 A CA002392090 A CA 002392090A CA 2392090 A CA2392090 A CA 2392090A CA 2392090 A1 CA2392090 A1 CA 2392090A1
Authority
CA
Canada
Prior art keywords
seq
polypeptide
mch
nucleic acid
expression vector
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002392090A
Other languages
English (en)
French (fr)
Inventor
Qingyun Liu
Terrence P. Mcdonald
Andrew D. Howard
Hisashi Iwaasa
Hideki Sano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MSD KK
Merck and Co Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2392090A1 publication Critical patent/CA2392090A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA002392090A 1999-11-16 2000-11-14 G-protein coupled receptor Abandoned CA2392090A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US16587199P 1999-11-16 1999-11-16
US60/165,871 1999-11-16
US18897700P 2000-03-13 2000-03-13
US60/188,977 2000-03-13
US19802900P 2000-04-18 2000-04-18
US60/198,029 2000-04-18
PCT/US2000/031240 WO2001036479A1 (en) 1999-11-16 2000-11-14 G-protein coupled receptor

Publications (1)

Publication Number Publication Date
CA2392090A1 true CA2392090A1 (en) 2001-05-25

Family

ID=27389191

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002392090A Abandoned CA2392090A1 (en) 1999-11-16 2000-11-14 G-protein coupled receptor

Country Status (5)

Country Link
US (1) US6593108B1 (enExample)
EP (1) EP1233981A4 (enExample)
JP (1) JP2003514549A (enExample)
CA (1) CA2392090A1 (enExample)
WO (1) WO2001036479A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001062797A2 (en) * 2000-02-23 2001-08-30 Pharmacia & Upjohn Company G protein-coupled receptors
JP4780365B2 (ja) * 2000-07-05 2011-09-28 武田薬品工業株式会社 Mch受容体アンタゴニスト・アゴニストのスクリーニング方法
DE60143525D1 (de) 2000-07-05 2011-01-05 Takeda Pharmaceutical Verfahren zum screenen von mhc-rezeptorantagonisten oder -agonisten
US6809104B2 (en) 2001-05-04 2004-10-26 Tularik Inc. Fused heterocyclic compounds
US7208282B2 (en) * 2001-05-31 2007-04-24 Merck & Co., Inc. Rhesus monkey, dog and ferret melanin-concentrating hormone type 2 receptor
US7141391B2 (en) 2001-11-13 2006-11-28 Neurogen Corporation Monkey and canine melanin concentrating hormone receptors
PL376659A1 (pl) 2002-11-06 2006-01-09 Tularik Inc. Skondensowane związki heterocykliczne
KR100820095B1 (ko) 2006-12-14 2008-04-07 부경대학교 산학협력단 양식 넙치의 멜라닌 농축 호르몬 수용체

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9214857D0 (en) * 1992-07-13 1992-08-26 Medical Res Council Human nucleic acid fragments and their use
US5686597A (en) 1995-06-06 1997-11-11 Incyte Pharmaceuticals, Inc. Thrombin receptor homolog
EP0848060A3 (en) 1996-12-11 2000-02-02 Smithkline Beecham Corporation Novel human 11CB splice variant
EP1153932A1 (en) * 1999-02-19 2001-11-14 Takeda Chemical Industries, Ltd. Novel g protein-coupled receptor protein and dna thereof
CA2296792A1 (en) 1999-02-26 2000-08-26 Genset S.A. Expressed sequence tags and encoded human proteins
WO2001007611A2 (en) 1999-07-26 2001-02-01 Genentech, Inc. Novel polynucleotides and method for the use thereof
WO2001007606A1 (en) 1999-07-27 2001-02-01 Smithkline Beecham Plc Axor21, a g-protein coupled receptor
IL149569A0 (en) * 1999-11-17 2002-11-10 Arena Pharm Inc Endogenous and non-endogenous versions of human g protein-coupled receptors
WO2001062797A2 (en) * 2000-02-23 2001-08-30 Pharmacia & Upjohn Company G protein-coupled receptors
JP2005229804A (ja) 2000-03-24 2005-09-02 Astellas Pharma Inc 新規なメラニンコンセントレーティングホルモン受容体

Also Published As

Publication number Publication date
WO2001036479A1 (en) 2001-05-25
EP1233981A4 (en) 2003-02-12
EP1233981A1 (en) 2002-08-28
US6593108B1 (en) 2003-07-15
JP2003514549A (ja) 2003-04-22

Similar Documents

Publication Publication Date Title
US6599718B1 (en) Growth hormone secretagogue related receptors and nucleic acids
US7198910B1 (en) Nucleic acid encoding melanin-concentrating hormone receptor
US6593108B1 (en) Nucleic acid molecule encoding a melanin-concentrating hormone receptor 2 polypeptide
JPH10295376A (ja) ヒトgpr14レセプターのクローニング
EP0897980A2 (en) CXCR4B: A human splice variant of CXCR4 chemokine receptor
WO2000050563A9 (en) G protein-coupled receptor resembling galanin receptors
US6344342B1 (en) Human G protein coupled lysophosphatidic acid receptor
US7208282B2 (en) Rhesus monkey, dog and ferret melanin-concentrating hormone type 2 receptor
US7148026B2 (en) Dog melanin-concentrating hormone receptor
US7074594B2 (en) Guanosine triphosphate (GTP) binding protein-coupled receptor proteins
US20040248129A1 (en) Rhesus monkey, dog and feeret melanin-concentrating hormone type 1 receptor
EP1095275B1 (en) Endogenous constitutively activated g protein-coupled orphan receptors
WO2001068706A1 (en) Melanin concentrating hormone receptor chimeric and fusion proteins
US20050069883A1 (en) Melanin-concentrating hormone receptor antagonist binding protein
US20020150901A1 (en) Novel nucleic acids, polypeptides, methods of making, and uses thereof
EP1012281B1 (en) Human leukocyte calcium activated potassium channel polypeptide
CA2427763A1 (en) Cell lines expressing a mch receptor
US7029878B2 (en) Melanin concentrating hormone receptor chimeric and fusion proteins
CA2389329A1 (en) Dog and rabbit motilin receptor orthologs
JP2004522422A (ja) Mch受容体を発現する細胞系

Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead