CA2390548A1 - Ing2, an iaps associated cell cycle protein, compositions and methods of use - Google Patents
Ing2, an iaps associated cell cycle protein, compositions and methods of use Download PDFInfo
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- CA2390548A1 CA2390548A1 CA002390548A CA2390548A CA2390548A1 CA 2390548 A1 CA2390548 A1 CA 2390548A1 CA 002390548 A CA002390548 A CA 002390548A CA 2390548 A CA2390548 A CA 2390548A CA 2390548 A1 CA2390548 A1 CA 2390548A1
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- cell cycle
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- 230000006916 protein interaction Effects 0.000 description 1
- 108060006633 protein kinase Proteins 0.000 description 1
- 229940076155 protein modulator Drugs 0.000 description 1
- 238000001742 protein purification Methods 0.000 description 1
- 230000002797 proteolythic effect Effects 0.000 description 1
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- 238000011002 quantification Methods 0.000 description 1
- IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 description 1
- 230000002285 radioactive effect Effects 0.000 description 1
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- 230000009711 regulatory function Effects 0.000 description 1
- 238000004007 reversed phase HPLC Methods 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- PYWVYCXTNDRMGF-UHFFFAOYSA-N rhodamine B Chemical compound [Cl-].C=12C=CC(=[N+](CC)CC)C=C2OC2=CC(N(CC)CC)=CC=C2C=1C1=CC=CC=C1C(O)=O PYWVYCXTNDRMGF-UHFFFAOYSA-N 0.000 description 1
- 150000003290 ribose derivatives Chemical group 0.000 description 1
- 210000003705 ribosome Anatomy 0.000 description 1
- 229960004889 salicylic acid Drugs 0.000 description 1
- 238000013391 scatchard analysis Methods 0.000 description 1
- 150000003335 secondary amines Chemical class 0.000 description 1
- 238000005204 segregation Methods 0.000 description 1
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- 210000002966 serum Anatomy 0.000 description 1
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- 125000001424 substituent group Chemical group 0.000 description 1
- 125000000547 substituted alkyl group Chemical group 0.000 description 1
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- 208000024891 symptom Diseases 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
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- 235000002906 tartaric acid Nutrition 0.000 description 1
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 description 1
- 230000002123 temporal effect Effects 0.000 description 1
- 208000001608 teratocarcinoma Diseases 0.000 description 1
- ISXSCDLOGDJUNJ-UHFFFAOYSA-N tert-butyl prop-2-enoate Chemical compound CC(C)(C)OC(=O)C=C ISXSCDLOGDJUNJ-UHFFFAOYSA-N 0.000 description 1
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- 229960002180 tetracycline Drugs 0.000 description 1
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- 235000019364 tetracycline Nutrition 0.000 description 1
- 150000003522 tetracyclines Chemical class 0.000 description 1
- JGVWCANSWKRBCS-UHFFFAOYSA-N tetramethylrhodamine thiocyanate Chemical compound [Cl-].C=12C=CC(N(C)C)=CC2=[O+]C2=CC(N(C)C)=CC=C2C=1C1=CC=C(SC#N)C=C1C(O)=O JGVWCANSWKRBCS-UHFFFAOYSA-N 0.000 description 1
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- 235000008521 threonine Nutrition 0.000 description 1
- 229940104230 thymidine Drugs 0.000 description 1
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- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
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- 108010044292 tryptophyltyrosine Proteins 0.000 description 1
- MEYZYGMYMLNUHJ-UHFFFAOYSA-N tunicamycin Natural products CC(C)CCCCCCCCCC=CC(=O)NC1C(O)C(O)C(CC(O)C2OC(C(O)C2O)N3C=CC(=O)NC3=O)OC1OC4OC(CO)C(O)C(O)C4NC(=O)C MEYZYGMYMLNUHJ-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4747—Apoptosis related proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/442,013 | 1999-11-17 | ||
| US09/442,013 US6737232B1 (en) | 1999-11-17 | 1999-11-17 | IAPs associated cell cycle proteins, compositions and methods of use |
| PCT/US2000/031698 WO2001036476A2 (en) | 1999-11-17 | 2000-11-17 | Ing2, an iaps associated cell cycle protein, compositions and methods of use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2390548A1 true CA2390548A1 (en) | 2001-05-25 |
Family
ID=23755177
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002390548A Abandoned CA2390548A1 (en) | 1999-11-17 | 2000-11-17 | Ing2, an iaps associated cell cycle protein, compositions and methods of use |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US6737232B1 (enExample) |
| EP (1) | EP1237916B1 (enExample) |
| JP (1) | JP2003514548A (enExample) |
| AT (1) | ATE290549T1 (enExample) |
| AU (1) | AU1660501A (enExample) |
| CA (1) | CA2390548A1 (enExample) |
| DE (1) | DE60018605T2 (enExample) |
| WO (1) | WO2001036476A2 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5640237B2 (ja) * | 1999-11-30 | 2014-12-17 | ルードヴィッヒ インスティテュート フォー キャンサー リサーチ リミテッド | 癌関連抗原をコードする単離された核酸分子、その抗原そのものおよびその使用 |
| US7172880B2 (en) * | 2001-01-08 | 2007-02-06 | The Burnham Institute For Medical Research | Inhibitor of apoptosis proteins and nucleic acids and methods for making and using them |
| US6902902B2 (en) | 2001-11-27 | 2005-06-07 | Arena Pharmaceuticals, Inc. | Human G protein-coupled receptors and modulators thereof for the treatment of metabolic-related disorders |
| WO2003062398A2 (en) * | 2002-01-23 | 2003-07-31 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | NEW TUMOR SUPPRESSOR GENE, p28ING5 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH08510325A (ja) * | 1993-05-28 | 1996-10-29 | カイロン コーポレイション | 生物学的に活性なペプチド配列の選択方法 |
| US6117633A (en) | 1995-12-08 | 2000-09-12 | University Technologies International Inc. | DNA sequence encoding the tumor suppressor gene ING1 |
| EP0970210A1 (en) | 1997-03-27 | 2000-01-12 | University Technologies International Inc. | Methods of modulating p33ing1 mediated apoptosis |
| US6066474A (en) | 1998-11-18 | 2000-05-23 | The Research Foundation Of State University Of New York | Y2H56 A strong IKK binding protein |
-
1999
- 1999-11-17 US US09/442,013 patent/US6737232B1/en not_active Expired - Lifetime
-
2000
- 2000-11-16 US US09/715,725 patent/US7423118B1/en not_active Expired - Fee Related
- 2000-11-17 AU AU16605/01A patent/AU1660501A/en not_active Abandoned
- 2000-11-17 JP JP2001538965A patent/JP2003514548A/ja active Pending
- 2000-11-17 CA CA002390548A patent/CA2390548A1/en not_active Abandoned
- 2000-11-17 US US10/130,555 patent/US7420045B1/en not_active Expired - Fee Related
- 2000-11-17 DE DE60018605T patent/DE60018605T2/de not_active Expired - Fee Related
- 2000-11-17 WO PCT/US2000/031698 patent/WO2001036476A2/en not_active Ceased
- 2000-11-17 EP EP00979200A patent/EP1237916B1/en not_active Expired - Lifetime
- 2000-11-17 AT AT00979200T patent/ATE290549T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU1660501A (en) | 2001-05-30 |
| WO2001036476A2 (en) | 2001-05-25 |
| US7423118B1 (en) | 2008-09-09 |
| WO2001036476A3 (en) | 2001-11-22 |
| DE60018605T2 (de) | 2006-01-19 |
| EP1237916A2 (en) | 2002-09-11 |
| DE60018605D1 (de) | 2005-04-14 |
| EP1237916B1 (en) | 2005-03-09 |
| US7420045B1 (en) | 2008-09-02 |
| JP2003514548A (ja) | 2003-04-22 |
| US6737232B1 (en) | 2004-05-18 |
| ATE290549T1 (de) | 2005-03-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |