CA2389117A1 - Procedes et compositions ameliorant le potentiel de developpement d'oocytes et de zygotes - Google Patents

Procedes et compositions ameliorant le potentiel de developpement d'oocytes et de zygotes Download PDF

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Publication number
CA2389117A1
CA2389117A1 CA002389117A CA2389117A CA2389117A1 CA 2389117 A1 CA2389117 A1 CA 2389117A1 CA 002389117 A CA002389117 A CA 002389117A CA 2389117 A CA2389117 A CA 2389117A CA 2389117 A1 CA2389117 A1 CA 2389117A1
Authority
CA
Canada
Prior art keywords
mitochondria
replicative
oocytes
donor cell
derived
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002389117A
Other languages
English (en)
Inventor
Robert F. Casper
Ian Rogers
Jonathan Tilly
Andrea Jurisicova
Gloria I. Perez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mount Sinai Hospital Corp
General Hospital Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2389117A1 publication Critical patent/CA2389117A1/fr
Abandoned legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027New or modified breeds of vertebrates
    • A01K67/0271Chimeric vertebrates, e.g. comprising exogenous cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2517/00Cells related to new breeds of animals
    • C12N2517/10Conditioning of cells for in vitro fecondation or nuclear transfer

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne des compositions et des procédés améliorant le potentiel de développement d'oocytes ou de zygotes par augmentation des niveaux intracellulaires de mitochondries réplicatives dans les oocytes ou les zygotes. Selon un aspect de l'invention, les niveaux intracellulaires de mitochondries réplicatives sont augmentés par introduction de mitochondries réplicatives dans les oocytes ou les zygotes. Les oocytes peuvent être fécondés afin d'obtenir un zygote à niveaux intracellulaires augmentés de mitochondries réplicatives. On peut utiliser les procédés et compositions selon l'invention pour améliorer les procédés de fécondation in vitro et de transfert d'embryon, ainsi que les techniques de transfert de matériel nucléaire.
CA002389117A 1999-10-27 2000-10-27 Procedes et compositions ameliorant le potentiel de developpement d'oocytes et de zygotes Abandoned CA2389117A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16179799P 1999-10-27 1999-10-27
US60/161,797 1999-10-27
PCT/CA2000/001283 WO2001030980A2 (fr) 1999-10-27 2000-10-27 Procedes et compositions ameliorant le potentiel de developpement d'oocytes et de zygotes

Publications (1)

Publication Number Publication Date
CA2389117A1 true CA2389117A1 (fr) 2001-05-03

Family

ID=22582774

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002389117A Abandoned CA2389117A1 (fr) 1999-10-27 2000-10-27 Procedes et compositions ameliorant le potentiel de developpement d'oocytes et de zygotes

Country Status (5)

Country Link
EP (1) EP1234021A2 (fr)
JP (1) JP2003512833A (fr)
AU (1) AU1123301A (fr)
CA (1) CA2389117A1 (fr)
WO (1) WO2001030980A2 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1442115B9 (fr) 2001-11-15 2009-12-16 Children's Medical Center Corporation Techniques d'isolation, de developpement et de differenciation de cellules souches provenant de villosites choriales, de liquide amniotique ainsi que de placenta et applications therapeutiques
GB0200804D0 (en) 2002-01-14 2002-03-06 Univ Birmingham Cloning methods and other methods of producing cells
US7955846B2 (en) 2004-05-17 2011-06-07 The General Hospital Corporation Compositions comprising female germline stem cells and methods of use thereof
CA2897658A1 (fr) 2004-05-17 2005-12-22 The General Hospital Corporation Compositions comprenant des cellules souches germinales femelles et leurs procedes d'utilisation
EP2697365A4 (fr) * 2011-04-14 2014-07-23 Gen Hospital Corp Compositions et méthodes de transfert d'énergie autologue des mitochondries dans les cellules germinales
AU2014202447B2 (en) * 2011-04-14 2015-05-07 The General Hospital Corporation Compositions and methods for autologous germline mitochondrial energy transfer
EA201490050A1 (ru) 2011-06-29 2014-07-30 Зе Дженерэл Хоспитэл Корпорейшн Композиции и способы повышения биоэнергетического состояния женских зародышевых клеток
WO2019113743A1 (fr) * 2017-12-11 2019-06-20 清华大学 Procédé de modification génétique
CN114214270B (zh) * 2021-12-17 2023-11-24 中国农业科学院北京畜牧兽医研究所 一种调控冷冻牛卵母细胞的发育能力的方法及其应用

Also Published As

Publication number Publication date
EP1234021A2 (fr) 2002-08-28
WO2001030980A2 (fr) 2001-05-03
WO2001030980A3 (fr) 2001-11-29
AU1123301A (en) 2001-05-08
JP2003512833A (ja) 2003-04-08

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