CA2385879A1 - Proteines du cycle cellulaire associees a la traf4, compositions et modalites d'utilisation - Google Patents

Proteines du cycle cellulaire associees a la traf4, compositions et modalites d'utilisation Download PDF

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Publication number
CA2385879A1
CA2385879A1 CA002385879A CA2385879A CA2385879A1 CA 2385879 A1 CA2385879 A1 CA 2385879A1 CA 002385879 A CA002385879 A CA 002385879A CA 2385879 A CA2385879 A CA 2385879A CA 2385879 A1 CA2385879 A1 CA 2385879A1
Authority
CA
Canada
Prior art keywords
protein
cell cycle
mkinase
cell
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002385879A
Other languages
English (en)
Inventor
Ying Luo
Xiang Xu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rigel Pharmaceuticals Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2385879A1 publication Critical patent/CA2385879A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4738—Cell cycle regulated proteins, e.g. cyclin, CDC, INK-CCR
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

La présente invention concerne des polypeptides, des acides nucléiques et des molécules s'y rapportant et agissant sur le cycle cellulaire ou s'y rapportant. L'invention concerne également des vecteurs et cellules hôtes comprenant ces séquences d'acides nucléiques, des séquences de polypeptides chimériques comprenant les polypeptides de l'invention fusionnés avec des séquences de polypeptides hétérologues, des anticorps qui se lient aux polypeptides de l'invention, et des procédés permettant la production des polypeptides de l'invention. L'invention concerne enfin des procédés d'identification de compositions de l'invention médiatrices de la bioactivité du cycle cellulaire, et l'utilisation de ces compositions pour le diagnostic et le traitement de maladies.
CA002385879A 1999-09-23 2000-09-25 Proteines du cycle cellulaire associees a la traf4, compositions et modalites d'utilisation Abandoned CA2385879A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US40401099A 1999-09-23 1999-09-23
US09/404,010 1999-09-23
PCT/US2000/040987 WO2001021799A1 (fr) 1999-09-23 2000-09-25 Proteines du cycle cellulaire associees a la traf4, compositions et modalites d'utilisation

Publications (1)

Publication Number Publication Date
CA2385879A1 true CA2385879A1 (fr) 2001-03-29

Family

ID=23597764

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002385879A Abandoned CA2385879A1 (fr) 1999-09-23 2000-09-25 Proteines du cycle cellulaire associees a la traf4, compositions et modalites d'utilisation

Country Status (5)

Country Link
EP (1) EP1218506A1 (fr)
JP (1) JP2003510049A (fr)
AU (1) AU1366901A (fr)
CA (1) CA2385879A1 (fr)
WO (1) WO2001021799A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6562591B1 (en) 1999-10-21 2003-05-13 Rigel Pharmaceuticals, Inc. Germinal center kinase cell cycle proteins, compositions and methods of use
KR101542301B1 (ko) 2013-06-21 2015-08-06 영남대학교 산학협력단 Ｔｒａｆ４ ｔｒａｆ 도메인의 ３차 구조
CN111214647B (zh) * 2020-01-08 2023-02-14 中山大学附属第八医院（深圳福田） 一种治疗强直性脊柱炎的药物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69233399T2 (de) * 1991-09-20 2005-08-04 Fred Hutchinson Cancer Research Center, Seattle Menschliches cyclin e
ZA966663B (en) * 1995-08-17 1998-02-06 Genentech Inc Traf Inhibitors.
ATE297983T1 (de) * 1997-07-21 2005-07-15 Arpi Matossian-Rogers Diagnose und behandlung von krankheiten mittels anti-t-zell rezeptor-vbeta-antikörper oder peptide, an denen diese antikörper spezifisch binden, und esrp1
US6143507A (en) * 1998-10-29 2000-11-07 Boehringer Ingelheim Pharmaceuticals, Inc. High throughput compatible assay for receptor-TRAF interactions

Also Published As

Publication number Publication date
WO2001021799A9 (fr) 2002-08-08
WO2001021799B1 (fr) 2001-10-11
JP2003510049A (ja) 2003-03-18
WO2001021799A1 (fr) 2001-03-29
EP1218506A1 (fr) 2002-07-03
AU1366901A (en) 2001-04-24

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Legal Events

Date Code Title Description
FZDE Dead