CA2383615A1 - Procedes de diagnostic et de therapie de malignites hematologiques ou associees aux virus - Google Patents
Procedes de diagnostic et de therapie de malignites hematologiques ou associees aux virus Download PDFInfo
- Publication number
- CA2383615A1 CA2383615A1 CA002383615A CA2383615A CA2383615A1 CA 2383615 A1 CA2383615 A1 CA 2383615A1 CA 002383615 A CA002383615 A CA 002383615A CA 2383615 A CA2383615 A CA 2383615A CA 2383615 A1 CA2383615 A1 CA 2383615A1
- Authority
- CA
- Canada
- Prior art keywords
- patient
- her2
- neu
- cells
- polypeptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Microbiology (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Mycology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
La présente invention concerne des procédés de détection et de traitement de malignités associées aux virus au moyen des séquences Her2/neu. Les Her2/neu peuvent se présenter comme des polypeptides ou des polynucléotides.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US40444399A | 1999-09-22 | 1999-09-22 | |
US09/404,443 | 1999-09-22 | ||
PCT/US2000/026110 WO2001021192A2 (fr) | 1999-09-22 | 2000-09-22 | Procedes de diagnostic et de therapie de malignites hematologiques ou associees aux virus |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2383615A1 true CA2383615A1 (fr) | 2001-03-29 |
Family
ID=23599624
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002383615A Abandoned CA2383615A1 (fr) | 1999-09-22 | 2000-09-22 | Procedes de diagnostic et de therapie de malignites hematologiques ou associees aux virus |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1214595A2 (fr) |
AU (1) | AU7710300A (fr) |
CA (1) | CA2383615A1 (fr) |
WO (1) | WO2001021192A2 (fr) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU1490801A (en) * | 1999-11-15 | 2001-05-30 | University Of Southern California | Targeted delivery of therapeutic and diagnostic moieties |
AU2744201A (en) * | 1999-12-29 | 2001-07-09 | Corixa Corporation | Murine neu sequences and methods of use therefor |
CA2407556C (fr) | 2000-05-19 | 2011-06-21 | Genentech, Inc. | Analyse de detection genique permettant d'ameliorer la probabilite d'une reponse efficace a une therapie du cancer basee sur un antagoniste d'erbb |
WO2002013847A2 (fr) * | 2000-08-14 | 2002-02-21 | Corixa Corporation | Methodes diagnostiques et therapeutiques des tumeurs malignes d'origine hematologiques et virales |
EP1613736A4 (fr) * | 2003-03-11 | 2007-04-11 | Dana Farber Cancer Inst Inc | Inhibition de la pathogenese virale |
BRPI0518104B8 (pt) | 2005-01-21 | 2021-05-25 | Genentech Inc | artigo industrializado e uso de anticorpo her2 |
UA95902C2 (ru) | 2005-02-23 | 2011-09-26 | Дженентек, Инк. | Способ увеличения времени развития заболевания или выживаемости у раковых пациентов |
CA2677108A1 (fr) | 2007-03-02 | 2008-09-12 | Genentech, Inc. | Element de prevision de la reponse a un inhibiteur de her |
US9551033B2 (en) | 2007-06-08 | 2017-01-24 | Genentech, Inc. | Gene expression markers of tumor resistance to HER2 inhibitor treatment |
EP2171090B1 (fr) | 2007-06-08 | 2013-04-03 | Genentech, Inc. | Marqueurs d'expression de gène de résistance tumorale à un traitement par inhibiteur her2 |
BRPI0812682A2 (pt) | 2008-06-16 | 2010-06-22 | Genentech Inc | tratamento de cáncer de mama metastático |
RU2504553C2 (ru) | 2009-03-20 | 2014-01-20 | Дженентек, Инк. | Антитела к her |
WO2010136569A1 (fr) | 2009-05-29 | 2010-12-02 | F. Hoffmann-La Roche Ag | Modulateurs de la signalisation her2 chez des patients exprimant her2 souffrant d'un cancer de l'estomac |
SI2536748T1 (sl) | 2010-02-18 | 2014-12-31 | Genentech, Inc. | Nevrogulinski antagonisti in njihova uporaba pri zdravljenju raka |
WO2011146568A1 (fr) | 2010-05-19 | 2011-11-24 | Genentech, Inc. | Prédiction de réponses à un inhibiteur de her |
CA2798837A1 (fr) | 2010-06-07 | 2011-12-15 | Pfizer Inc. | Peptides her-2 et vaccins |
WO2012069466A1 (fr) | 2010-11-24 | 2012-05-31 | Novartis Ag | Molécules multi-spécifiques |
JP5766296B2 (ja) | 2010-12-23 | 2015-08-19 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | ポリペプチド−ポリヌクレオチド複合体、およびエフェクター成分の標的化された送達におけるその使用 |
KR20140057326A (ko) | 2011-08-17 | 2014-05-12 | 제넨테크, 인크. | 뉴레귤린 항체 및 그의 용도 |
WO2013063229A1 (fr) | 2011-10-25 | 2013-05-02 | The Regents Of The University Of Michigan | Traitement par un agent de ciblage de her2 dans des cancers non amplifiés par her2 ayant des cellules souches cancéreuses exprimant her2 |
KR20140098834A (ko) | 2011-11-30 | 2014-08-08 | 제넨테크, 인크. | 암에서의 erbb3 돌연변이 |
US9376715B2 (en) | 2011-12-09 | 2016-06-28 | Roche Molecular Systems, Inc | Methods for detecting mutations in the catalytic subunit of the phosphoinositol-3 kinase (PIK3CA) gene |
BR112014024017A8 (pt) | 2012-03-27 | 2017-07-25 | Genentech Inc | Métodos de tratamento de um tipo de câncer, de tratamento do carcinoma, para selecionar uma terapia e para quantificação e inibidor de her3 |
KR102291355B1 (ko) | 2012-11-30 | 2021-08-19 | 에프. 호프만-라 로슈 아게 | Pd-l1 억제제 공동치료를 필요로 하는 환자의 식별방법 |
WO2017194554A1 (fr) | 2016-05-10 | 2017-11-16 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Polythérapies pour le traitement du cancer |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5801005A (en) * | 1993-03-17 | 1998-09-01 | University Of Washington | Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated |
US5869445A (en) * | 1993-03-17 | 1999-02-09 | University Of Washington | Methods for eliciting or enhancing reactivity to HER-2/neu protein |
EP0711565B1 (fr) * | 1994-11-10 | 1998-08-26 | Eberhard-Karls-Universität Tübingen Universitätsklinikum | Inhibition de la croissance des cellules leucemiques par ciblage de la protéine HER-2 |
-
2000
- 2000-09-22 EP EP00966815A patent/EP1214595A2/fr not_active Withdrawn
- 2000-09-22 AU AU77103/00A patent/AU7710300A/en not_active Abandoned
- 2000-09-22 CA CA002383615A patent/CA2383615A1/fr not_active Abandoned
- 2000-09-22 WO PCT/US2000/026110 patent/WO2001021192A2/fr not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP1214595A2 (fr) | 2002-06-19 |
AU7710300A (en) | 2001-04-24 |
WO2001021192A2 (fr) | 2001-03-29 |
WO2001021192A3 (fr) | 2001-08-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Discontinued |