CA2373336A1 - Peroxynitrite decomposition catalysts and methods of use thereof - Google Patents

Peroxynitrite decomposition catalysts and methods of use thereof Download PDF

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Publication number
CA2373336A1
CA2373336A1 CA002373336A CA2373336A CA2373336A1 CA 2373336 A1 CA2373336 A1 CA 2373336A1 CA 002373336 A CA002373336 A CA 002373336A CA 2373336 A CA2373336 A CA 2373336A CA 2373336 A1 CA2373336 A1 CA 2373336A1
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CA
Canada
Prior art keywords
complex
formula
moiety
peroxynitrite
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002373336A
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English (en)
French (fr)
Inventor
Suzanne M. Moeller
John T. Groves
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Princeton University
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2373336A1 publication Critical patent/CA2373336A1/en
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic System
    • C07F13/005—Compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
    • C07F15/02—Iron compounds
    • C07F15/025—Iron compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
    • C07F15/04—Nickel compounds
    • C07F15/045—Nickel compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/005—Compounds of elements of Group 5 of the Periodic System without metal-carbon linkages
CA002373336A 1999-06-03 2000-06-02 Peroxynitrite decomposition catalysts and methods of use thereof Abandoned CA2373336A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US13730899P 1999-06-03 1999-06-03
US60/137,308 1999-06-03
US09/587,382 US6448239B1 (en) 1999-06-03 2000-06-01 Peroxynitrite decomposition catalysts and methods of use thereof
US09/587,382 2000-06-01
PCT/US2000/015269 WO2000075144A2 (en) 1999-06-03 2000-06-02 Peroxynitrite decomposition catalysts and methods of use thereof

Publications (1)

Publication Number Publication Date
CA2373336A1 true CA2373336A1 (en) 2000-12-14

Family

ID=26835128

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002373336A Abandoned CA2373336A1 (en) 1999-06-03 2000-06-02 Peroxynitrite decomposition catalysts and methods of use thereof

Country Status (6)

Country Link
US (3) US6448239B1 (US06448239-20020910-C00006.png)
EP (1) EP1185532A1 (US06448239-20020910-C00006.png)
JP (1) JP2003501432A (US06448239-20020910-C00006.png)
AU (1) AU780118B2 (US06448239-20020910-C00006.png)
CA (1) CA2373336A1 (US06448239-20020910-C00006.png)
WO (1) WO2000075144A2 (US06448239-20020910-C00006.png)

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Publication number Priority date Publication date Assignee Title
US7432369B2 (en) 2004-03-29 2008-10-07 Inotek Pharmaceuticals Corporation Pyridyl-substituted porphyrin compounds and methods of use thereof

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JP2005508864A (ja) 2001-06-01 2005-04-07 ナショナル・ジュウィッシュ・メディカル・アンド・リサーチ・センター 糖尿病の治療、または移植術における使用、または免疫寛容の誘導のためのオキシダントスカベンジャー
DE10240343A1 (de) * 2002-08-27 2004-03-11 Schering Ag Peroxynitrit-Umlagerungskatalysatoren
US20040127479A1 (en) * 2002-08-27 2004-07-01 Merck Patent Gmbh Peroxynitrite rearrangement catalysts
GB2397067B (en) * 2002-12-23 2005-05-11 Destiny Pharma Ltd Porphin & azaporphin derivatives with at least one cationic-nitrogen-containing meso-substituent for use in photodynamic therapy & in vitro sterilisation
US20050025804A1 (en) * 2003-07-28 2005-02-03 Adam Heller Reduction of adverse inflammation
US7299082B2 (en) 2003-10-31 2007-11-20 Abbott Diabetes Care, Inc. Method of calibrating an analyte-measurement device, and associated methods, devices and systems
US7699964B2 (en) 2004-02-09 2010-04-20 Abbott Diabetes Care Inc. Membrane suitable for use in an analyte sensor, analyte sensor, and associated method
US8165651B2 (en) 2004-02-09 2012-04-24 Abbott Diabetes Care Inc. Analyte sensor, and associated system and method employing a catalytic agent
EP1718201B1 (en) * 2004-02-09 2016-09-14 Duke University Substituted porphyrins
GB2415372A (en) 2004-06-23 2005-12-28 Destiny Pharma Ltd Non photodynamical or sonodynamical antimicrobial use of porphyrins and azaporphyrins containing at least one cationic-nitrogen-containing substituent
CA2595236A1 (en) * 2005-01-19 2006-07-27 Pharmacyclics, Inc. A method for treating neurologic diseases
JP2006224318A (ja) * 2005-02-15 2006-08-31 Brother Ind Ltd インクジェット記録装置
EP1928467A4 (en) 2005-09-28 2009-11-04 Inotek Pharmaceuticals Corp N-BENZYL SUBSTITUTED PORPHYRIN PYRIDYL COMPOUNDS AND METHODS OF USE
US7885698B2 (en) 2006-02-28 2011-02-08 Abbott Diabetes Care Inc. Method and system for providing continuous calibration of implantable analyte sensors
WO2008094222A2 (en) * 2006-10-06 2008-08-07 Trustees Of Princeton Porphyrin catalysts and methods of use thereof
WO2008045358A1 (en) * 2006-10-06 2008-04-17 Trustees Of Princeton Porphyrin catalysts and methods of use thereof
SI2056675T1 (sl) 2006-10-12 2019-08-30 Galera Labs, Llc Postopki za zdravljenje oralnega mukozitisa
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US20120065181A1 (en) * 2009-05-26 2012-03-15 Warner David S Method of providing neuroprotection using substituted porphyrins
US20120135973A1 (en) * 2010-09-08 2012-05-31 Southern Illinois University Edwardsville Method for treating chronic pain
JP5823988B2 (ja) * 2011-01-31 2015-11-25 国立大学法人宇都宮大学 ポルフィリン型骨格を有する化合物の金属錯体の製造方法
US20140227184A1 (en) 2011-08-19 2014-08-14 The Trustees Of Princeton University C-halogen bond formation
CN103906756B (zh) 2011-09-26 2020-03-03 加莱拉实验室有限责任公司 用于治疗疾病的方法
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JP2016509016A (ja) 2013-02-13 2016-03-24 カリフォルニア インスティチュート オブ テクノロジー 金属酸化物のスルホン酸エステル及びその使用の方法
JP6154231B2 (ja) * 2013-07-22 2017-06-28 学校法人同志社 抗癌剤
US20160264512A1 (en) 2013-10-09 2016-09-15 The Trustees Of Princeton University C-halogen bond formation
CA2933166C (en) 2013-12-31 2020-10-27 Abbott Diabetes Care Inc. Self-powered analyte sensor and devices using the same
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WO2015153863A1 (en) * 2014-04-03 2015-10-08 John Wayne Kennedy Copper/zinc superoxide dismutase (sod) formulation for the treatment of traumas including amyotropic lateral sclerosis
US9364537B2 (en) 2014-08-22 2016-06-14 University Of Dayton Transition metal porphyrin complexes and methods of treatment using same
RS60558B1 (sr) 2015-08-11 2020-08-31 Galera Labs Llc Pentaaza makrociklični prstenasti kompleksi koji poseduju oralnu bioraspoloživost
KR20190130654A (ko) 2017-04-04 2019-11-22 바이오미매틱스 제이브이, 엘엘씨 방사선 요법 및/또는 화학요법 노출과 연관된 부작용의 치료 및/또는 예방을 위한 방법, 조성물, 및 키트
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7432369B2 (en) 2004-03-29 2008-10-07 Inotek Pharmaceuticals Corporation Pyridyl-substituted porphyrin compounds and methods of use thereof

Also Published As

Publication number Publication date
WO2000075144A2 (en) 2000-12-14
US6969707B2 (en) 2005-11-29
US6448239B1 (en) 2002-09-10
EP1185532A1 (en) 2002-03-13
WO2000075144A3 (en) 2001-06-28
US20030055032A1 (en) 2003-03-20
WO2000075144A9 (en) 2002-07-11
AU5460300A (en) 2000-12-28
AU780118B2 (en) 2005-03-03
US20060199792A1 (en) 2006-09-07
WO2000075144A8 (en) 2001-08-09
JP2003501432A (ja) 2003-01-14

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FZDE Discontinued