CA2372393A1 - Nouvelles proteines a action insulinoide utilisees dans le traitement du diabete - Google Patents

Nouvelles proteines a action insulinoide utilisees dans le traitement du diabete Download PDF

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Publication number
CA2372393A1
CA2372393A1 CA002372393A CA2372393A CA2372393A1 CA 2372393 A1 CA2372393 A1 CA 2372393A1 CA 002372393 A CA002372393 A CA 002372393A CA 2372393 A CA2372393 A CA 2372393A CA 2372393 A1 CA2372393 A1 CA 2372393A1
Authority
CA
Canada
Prior art keywords
protein
insulin
sequence
amino acid
residues
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002372393A
Other languages
English (en)
Inventor
Bassil I. Dahiyat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Xencor Inc
Original Assignee
Xencor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xencor Inc filed Critical Xencor Inc
Publication of CA2372393A1 publication Critical patent/CA2372393A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
CA002372393A 1999-05-19 2000-05-19 Nouvelles proteines a action insulinoide utilisees dans le traitement du diabete Abandoned CA2372393A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13493099P 1999-05-19 1999-05-19
US60/134,930 1999-05-19
PCT/US2000/013764 WO2000069901A2 (fr) 1999-05-19 2000-05-19 Nouvelles proteines a action insulinoide utilisees dans le traitement du diabete

Publications (1)

Publication Number Publication Date
CA2372393A1 true CA2372393A1 (fr) 2000-11-23

Family

ID=22465651

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002372393A Abandoned CA2372393A1 (fr) 1999-05-19 2000-05-19 Nouvelles proteines a action insulinoide utilisees dans le traitement du diabete

Country Status (4)

Country Link
JP (1) JP2003518917A (fr)
AU (1) AU5144400A (fr)
CA (1) CA2372393A1 (fr)
WO (1) WO2000069901A2 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1141014E (pt) 1999-01-06 2005-04-29 Genentech Inc Variante mutante do factor de crescimento semelhante a insulina (igf-i)
PT1141015E (pt) 1999-01-06 2009-10-13 Genentech Inc Variantes mutantes do factor de crescimento do tipo insulina (igf)i
ES2301547T3 (es) 2000-05-16 2008-07-01 Genentech, Inc. Tratamiento de trastornos del cartilago.
EP1644411A2 (fr) * 2003-07-11 2006-04-12 Novo Nordisk A/S Compositions d'insuline stabilisee
BRPI0717098B8 (pt) 2006-09-22 2021-05-25 Novo Nordisk As análogos de insulina humana resistentes à protease, composição farmacêutica e processo para sua preparação
EP2254905B1 (fr) 2008-03-14 2016-12-14 Novo Nordisk A/S Analogues de l insuline stabilisés une protéase
BRPI0910348B1 (pt) 2008-03-18 2021-06-29 Novo Nordisk A/S Insulina estabilizada em protease acilada, composição farmacêutica compreendendo a mesma e seus usos
JP2012511506A (ja) * 2008-12-09 2012-05-24 ノヴォ・ノルディスク・アー／エス 新規インスリンアナログ
EP2686003A2 (fr) * 2011-03-15 2014-01-22 Novo Nordisk A/S Analogues de l'insuline humaine et dérivés comprenant des substitutions de cystéine
ES2676065T3 (es) 2013-10-07 2018-07-16 Novo Nordisk A/S Nuevo derivado de un análogo de la insulina
IL300839B2 (en) 2016-12-16 2024-04-01 Novo Nordisk As Pharmaceutical preparations containing insulin
MA49896A (fr) * 2017-08-17 2020-06-24 Novo Nordisk As Nouveaux analogues d'insuline acylés et leurs utilisations
CN112843081B (zh) * 2021-02-02 2022-07-05 四川大学 一种dna四面体-白藜芦醇复合物及其制备方法和用途
CN112843082B (zh) * 2021-02-02 2022-07-05 四川大学 Dna四面体在制备治疗糖尿病的药物中的用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5268453A (en) * 1991-08-08 1993-12-07 Scios Inc. Tissue-selective insulin analogs

Also Published As

Publication number Publication date
WO2000069901A3 (fr) 2002-09-12
AU5144400A (en) 2000-12-05
WO2000069901A2 (fr) 2000-11-23
JP2003518917A (ja) 2003-06-17

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead