CA2371022A1 - Vaccins a base d'organismes commensaux oraux genetiquement modifies - Google Patents

Vaccins a base d'organismes commensaux oraux genetiquement modifies Download PDF

Info

Publication number
CA2371022A1
CA2371022A1 CA002371022A CA2371022A CA2371022A1 CA 2371022 A1 CA2371022 A1 CA 2371022A1 CA 002371022 A CA002371022 A CA 002371022A CA 2371022 A CA2371022 A CA 2371022A CA 2371022 A1 CA2371022 A1 CA 2371022A1
Authority
CA
Canada
Prior art keywords
pathogen
pertussis
oral
organism
host
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002371022A
Other languages
English (en)
Inventor
Song F. Lee
Scott A. Halperin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dalhousie University
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2371022A1 publication Critical patent/CA2371022A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/099Bordetella
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/235Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bordetella (G)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/46Streptococcus ; Enterococcus; Lactococcus
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA002371022A 1999-04-23 2000-04-21 Vaccins a base d'organismes commensaux oraux genetiquement modifies Abandoned CA2371022A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29813599A 1999-04-23 1999-04-23
US09/298,135 1999-04-23
PCT/US2000/010954 WO2000064457A1 (fr) 1999-04-23 2000-04-21 Vaccins a base d'organismes commensaux oraux genetiquement modifies

Publications (1)

Publication Number Publication Date
CA2371022A1 true CA2371022A1 (fr) 2000-11-02

Family

ID=23149202

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002371022A Abandoned CA2371022A1 (fr) 1999-04-23 2000-04-21 Vaccins a base d'organismes commensaux oraux genetiquement modifies

Country Status (3)

Country Link
AU (1) AU4485300A (fr)
CA (1) CA2371022A1 (fr)
WO (1) WO2000064457A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104892755B (zh) * 2014-04-08 2018-02-16 北京天成新脉生物技术有限公司 百日咳prn 蛋白单克隆抗体及其应用

Also Published As

Publication number Publication date
AU4485300A (en) 2000-11-10
WO2000064457A1 (fr) 2000-11-02

Similar Documents

Publication Publication Date Title
Confer et al. Mannheimia haemolytica in bovine respiratory disease: immunogens, potential immunogens, and vaccines
Haesebrouck et al. Actinobacillus pleuropneumoniae infections in pigs: the role of virulence factors in pathogenesis and protection
Hensel et al. Intramuscular immunization with genetically inactivated (ghosts) Actinobacillus pleuropneumoniae serotype 9 protects pigs against homologous aerosol challenge and prevents carrier state
JP5931724B2 (ja) StreptococcusPneumoniaeに対するワクチンおよび組成物
JP6084631B2 (ja) Clostridiumdifficile毒素ベースのワクチン
Wei et al. Immunogenicity and protective efficacy of orally or intranasally administered recombinant Lactobacillus casei expressing ETEC K99
Harokopakis et al. Mucosal immunogenicity of a recombinant Salmonella typhimurium-cloned heterologous antigen in the absence or presence of coexpressed cholera toxin A2 and B subunits
Dubreuil Pig vaccination strategies based on enterotoxigenic Escherichia coli toxins
JP4516210B2 (ja) ワクチンに使用する弱毒化細菌
Van Beek et al. Intranasal vaccination with protein bodies elicit strong protection against Streptococcus pneumoniae colonization
Angelos Moraxella
CN108025053A (zh) 百日咳杆菌免疫原性的疫苗组合物
US5798260A (en) Escherichia coli O157:H7 epithelial adhesin
EP0682950B1 (fr) Administration mucosale d'antigènes de pneumococcus
CN113329766A (zh) 艰难梭菌多组分疫苗
Richardson Animal models in cholera research
WO2019025517A1 (fr) Vaccin pour la protection contre streptococcus suis
Dale et al. Group A and group B streptococcal vaccine development: a round table presentation
WO1993010815A1 (fr) Mutants non encapsules de bacteries utiles comme vaccins
WO2021185680A1 (fr) Vaccin de protection contre streptococcus suis sérotype 9, séquence de type 16
CA2371022A1 (fr) Vaccins a base d'organismes commensaux oraux genetiquement modifies
Pérez et al. Passive protection of serum from volunteers inoculated with attenuated strain 638 of Vibrio cholerae O1 in animal models
Hur et al. Immunological study of an attenuated Salmonella Typhimurium expressing ApxIA, ApxIIA, ApxIIIA and OmpA of Actinobacillus pleuropneumoniae in a mouse model
Hara et al. Outer membrane proteins as potential candidate vaccine targets
CN101400783B9 (zh) 包特氏菌减毒活菌株作为抗百日咳的单剂量疫苗

Legal Events

Date Code Title Description
FZDE Dead