CA2369078A1 - Medicaments containing inhibitors of cell-volume regulated human kinase h-sgk - Google Patents
Medicaments containing inhibitors of cell-volume regulated human kinase h-sgk Download PDFInfo
- Publication number
- CA2369078A1 CA2369078A1 CA002369078A CA2369078A CA2369078A1 CA 2369078 A1 CA2369078 A1 CA 2369078A1 CA 002369078 A CA002369078 A CA 002369078A CA 2369078 A CA2369078 A CA 2369078A CA 2369078 A1 CA2369078 A1 CA 2369078A1
- Authority
- CA
- Canada
- Prior art keywords
- sgk
- inhibitor
- human cell
- medicament
- cell volume
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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Classifications
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
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Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Emergency Medicine (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Obesity (AREA)
- Gastroenterology & Hepatology (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19917990A DE19917990A1 (de) | 1999-04-20 | 1999-04-20 | Arzneimittel enthaltend Hemmstoffe der zellvolumenregulierten humanen Kinase h-sgk |
| DE19917990.5 | 1999-04-20 | ||
| PCT/EP2000/003578 WO2000062781A1 (de) | 1999-04-20 | 2000-04-19 | Arzneimittel enthaltend hemmstoffe der zellvolumenregulierten humanen kinase h-sgk |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2369078A1 true CA2369078A1 (en) | 2000-10-26 |
Family
ID=7905297
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002369078A Abandoned CA2369078A1 (en) | 1999-04-20 | 2000-04-19 | Medicaments containing inhibitors of cell-volume regulated human kinase h-sgk |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP1171131A1 (es) |
| JP (1) | JP2002542196A (es) |
| KR (1) | KR100718900B1 (es) |
| CN (1) | CN1351496A (es) |
| AU (1) | AU779941B2 (es) |
| BR (1) | BR0009914A (es) |
| CA (1) | CA2369078A1 (es) |
| CZ (1) | CZ20013778A3 (es) |
| DE (1) | DE19917990A1 (es) |
| HU (1) | HUP0200819A3 (es) |
| MX (1) | MXPA01010588A (es) |
| NO (1) | NO20015054L (es) |
| PL (1) | PL198427B1 (es) |
| RU (1) | RU2288718C9 (es) |
| SK (1) | SK14972001A3 (es) |
| UA (1) | UA79066C2 (es) |
| WO (1) | WO2000062781A1 (es) |
| ZA (1) | ZA200108610B (es) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10042137A1 (de) * | 2000-08-28 | 2002-03-14 | Florian Lang | sgk2 und sgk3 als diagnostische und therapeutische Targets |
| DE10113876A1 (de) * | 2001-03-21 | 2002-09-26 | Eberhard Karls Uni Medizinisch | Quantitative diagnostische Analyse der Hypertonie |
| CA2449794A1 (en) | 2001-04-27 | 2002-11-07 | Cold Spring Harbor Laboratory | Alleviation of the memory deficits and memory components of psychiatric dysfunctions by altering atypical pkm activity |
| DE10149393A1 (de) * | 2001-09-28 | 2003-04-24 | Florian Lang | sgk1 als diagnostisches und therapeutisches target |
| DE10225844A1 (de) * | 2002-06-04 | 2003-12-18 | Lang Florian | sgk und nedd als diagnostische und therapeutische targets |
| DE10305212A1 (de) * | 2003-02-07 | 2004-08-19 | Florian Prof. Dr.med. Lang | Verwendung der sgk-Genfamilie zur Diagnose und zur Therapie von Katarakt und Glaukom |
| WO2004079003A1 (de) * | 2003-03-03 | 2004-09-16 | Florian Lang | Sgk1 als diagnostisches und therapeutisches target |
| WO2004084889A1 (en) * | 2003-03-28 | 2004-10-07 | Pfizer Inc. | Use of protein kinase c inhibitor for suppressing sustained slow postsynaptic excitation (sspe) of enteric neurons |
| DE10346913A1 (de) * | 2003-10-09 | 2005-05-04 | Merck Patent Gmbh | Acylhydrazonderivate |
| WO2005084702A1 (ja) * | 2004-03-02 | 2005-09-15 | Hokkaido Technology Licensing Office Co., Ltd. | 臓器線維症予防・治療剤 |
| WO2005094796A2 (en) * | 2004-03-11 | 2005-10-13 | Merck Patent Gmbh | Methods for interfering with fibrosis |
| US20070191326A1 (en) * | 2004-03-11 | 2007-08-16 | Florian Lang | Methods for modulating glutamate receptors for treating neuropsychiatric disorders comprising the use of modulators of serum and glucocorticoid inducible kinases |
| US20090136920A1 (en) * | 2004-04-30 | 2009-05-28 | Stefan Golz | Diagnostics and therapeutics for diseases associated with serum/glucocorticoid regulated kinase 1 (sgk1) |
| WO2005118832A2 (en) * | 2004-06-01 | 2005-12-15 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with serum/glucocorticoid regulated kinase-like protein (sgkl) |
| DE102004030987A1 (de) * | 2004-06-26 | 2006-01-12 | Merck Patent Gmbh | Ortho-substituierte (3-Hydroxyphenyl)-essigsäure-benzyliden-hydrazide |
| MX2007001155A (es) * | 2004-07-29 | 2007-08-14 | Creabilis Therapeutics Spa | Uso de inhibidores de k-252a y de quinasa para la prevencion o el tratamiento de patologias asociadas con hmgb1. |
| DE102005001053A1 (de) * | 2005-01-07 | 2006-07-20 | Merck Patent Gmbh | Quadratsäurederivate |
| DE102005015255A1 (de) * | 2005-04-04 | 2006-10-05 | Merck Patent Gmbh | Acylhydrazide |
| DE102005035742A1 (de) * | 2005-07-29 | 2007-02-01 | Merck Patent Gmbh | Quadratsäurederivate II |
| DE102005039541A1 (de) * | 2005-08-22 | 2007-03-22 | Merck Patent Gmbh | 3-Oxo-indazol-quadratsäurederivate |
| DE102007002717A1 (de) | 2007-01-18 | 2008-07-24 | Merck Patent Gmbh | Heterocyclische Indazolderivate |
| DE102007022565A1 (de) | 2007-05-14 | 2008-11-20 | Merck Patent Gmbh | Heterocyclische Indazolderivate |
| EP2014651A1 (en) * | 2007-07-12 | 2009-01-14 | Exonhit Therapeutics SA | Compounds and methods for modulating Rho GTPases |
| DE102008010363A1 (de) | 2008-02-18 | 2009-08-20 | Lang, Florian, Prof. Dr.med. | Sgk1 als therapeutisches und diagnostisches Target für karzinomatöse Erkrankungen |
| DE102008010362A1 (de) | 2008-02-18 | 2009-08-20 | Florian Prof. Dr. Lang | Sgk1 als therapeutisches und diagnostisches Target für virale Erkrankungen |
| DE102008010361A1 (de) | 2008-02-18 | 2009-08-20 | Merck Patent Gmbh | sgk1-Inhibitoren zur Prophylaxe und/oder Therapie von viralen Erkrankungen und/oder Karzinomen |
| DE102008029072A1 (de) * | 2008-06-10 | 2009-12-17 | Lang, Florian, Prof. Dr.med. | Sgk3 als therapeutisches und diagnostisches Target für Alterserkrankungen |
| DE102008038222A1 (de) | 2008-08-18 | 2010-02-25 | Merck Patent Gmbh | Indazol-5-carbonsäurehydrazid-derivate |
| DE102008038220A1 (de) | 2008-08-18 | 2010-02-25 | Merck Patent Gmbh | Oxadiazolderivate |
| DE102008038221A1 (de) | 2008-08-18 | 2010-02-25 | Merck Patent Gmbh | 7-Azaindolderivate |
| DE102008059133A1 (de) | 2008-11-26 | 2010-05-27 | Merck Patent Gmbh | Difluorphenyl-diacylhydrazid-derivate |
| WO2012064981A2 (en) * | 2010-11-10 | 2012-05-18 | National Jewish Health | Methods to test allergic conditions |
| CN107875153A (zh) * | 2017-11-16 | 2018-04-06 | 上海壹志医药科技有限公司 | 去甲白屈菜红碱的药物用途 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5373501A (en) * | 1976-12-11 | 1978-06-30 | Kitasato Inst | Novel antibiotics amm2282 and process for preparing same |
| US5242397A (en) * | 1989-06-20 | 1993-09-07 | Cedars-Sinai Medical Center | Catheter device and method of use for intramural delivery of protein kinase C and tyrosine protein kinase inhibitors to prevent restenosis after balloon angioplasty |
| US5137912A (en) * | 1991-01-28 | 1992-08-11 | National Science Council Of Republic Of China | Chelerythrine inhibits platelet aggregation--a potential anti-aggregation drug |
| GB9325395D0 (en) * | 1993-12-11 | 1994-02-16 | Ciba Geigy Ag | Compositions |
| US5874464A (en) * | 1995-01-13 | 1999-02-23 | The United States Of America As Represented By The Department Of Health And Human Services | Conformationally constrained diacylglycerol analogues |
| AU6888196A (en) * | 1995-08-11 | 1997-03-12 | Yale University | Glycosylated indolocarbazole synthesis |
| PT906268E (pt) * | 1996-05-30 | 2002-05-31 | Aventis Pharma Inc | Fluorenonas com substituicao alquiloxiamino e sua utilizacao como inibidores da proteina quinase c |
| EP0887081B1 (en) * | 1997-06-27 | 2003-04-23 | Smithkline Beecham Corporation | Human serum glucocorticoid regulated kinase, a target for chronic renal disease and diabetic nephropathy |
| EP0889127A1 (en) * | 1997-07-01 | 1999-01-07 | Smithkline Beecham Corporation | Serine/threonine protein kinase (H-SGK2) |
| CO4940430A1 (es) * | 1997-07-07 | 2000-07-24 | Novartis Ag | Compuestos policiclicos que contienen estaurosporina hidrogenada con propiedades farmacologicas convenientes y un efecto inhibidor sobre el crecimiento de las celulas tumorales |
-
1999
- 1999-04-20 DE DE19917990A patent/DE19917990A1/de not_active Ceased
-
2000
- 2000-04-19 JP JP2000611917A patent/JP2002542196A/ja active Pending
- 2000-04-19 CZ CZ20013778A patent/CZ20013778A3/cs unknown
- 2000-04-19 PL PL352547A patent/PL198427B1/pl unknown
- 2000-04-19 WO PCT/EP2000/003578 patent/WO2000062781A1/de not_active Application Discontinuation
- 2000-04-19 CN CN00807959A patent/CN1351496A/zh active Pending
- 2000-04-19 HU HU0200819A patent/HUP0200819A3/hu unknown
- 2000-04-19 KR KR1020017013336A patent/KR100718900B1/ko not_active IP Right Cessation
- 2000-04-19 UA UA2001117896A patent/UA79066C2/uk unknown
- 2000-04-19 MX MXPA01010588A patent/MXPA01010588A/es not_active Application Discontinuation
- 2000-04-19 AU AU42972/00A patent/AU779941B2/en not_active Ceased
- 2000-04-19 SK SK1497-2001A patent/SK14972001A3/sk unknown
- 2000-04-19 RU RU2001131351/15A patent/RU2288718C9/ru not_active IP Right Cessation
- 2000-04-19 BR BR0009914-7A patent/BR0009914A/pt not_active Application Discontinuation
- 2000-04-19 CA CA002369078A patent/CA2369078A1/en not_active Abandoned
- 2000-04-19 EP EP00922655A patent/EP1171131A1/de not_active Withdrawn
-
2001
- 2001-10-17 NO NO20015054A patent/NO20015054L/no not_active Application Discontinuation
- 2001-10-19 ZA ZA200108610A patent/ZA200108610B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2002542196A (ja) | 2002-12-10 |
| WO2000062781A1 (de) | 2000-10-26 |
| HUP0200819A3 (en) | 2009-08-28 |
| DE19917990A1 (de) | 2000-11-02 |
| PL198427B1 (pl) | 2008-06-30 |
| UA79066C2 (en) | 2007-05-25 |
| PL352547A1 (en) | 2003-08-25 |
| CN1351496A (zh) | 2002-05-29 |
| NO20015054D0 (no) | 2001-10-17 |
| RU2288718C2 (ru) | 2006-12-10 |
| KR20020012172A (ko) | 2002-02-15 |
| SK14972001A3 (sk) | 2002-06-04 |
| KR100718900B1 (ko) | 2007-05-17 |
| HUP0200819A2 (hu) | 2002-07-29 |
| AU4297200A (en) | 2000-11-02 |
| ZA200108610B (en) | 2002-01-02 |
| NO20015054L (no) | 2001-12-14 |
| EP1171131A1 (de) | 2002-01-16 |
| CZ20013778A3 (cs) | 2002-06-12 |
| MXPA01010588A (es) | 2004-09-06 |
| BR0009914A (pt) | 2002-01-08 |
| AU779941B2 (en) | 2005-02-17 |
| RU2288718C9 (ru) | 2008-04-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |