CA2366789C - Fatty acid analogs for diagnosis of coronary artery disease - Google Patents
Fatty acid analogs for diagnosis of coronary artery disease Download PDFInfo
- Publication number
- CA2366789C CA2366789C CA2366789A CA2366789A CA2366789C CA 2366789 C CA2366789 C CA 2366789C CA 2366789 A CA2366789 A CA 2366789A CA 2366789 A CA2366789 A CA 2366789A CA 2366789 C CA2366789 C CA 2366789C
- Authority
- CA
- Canada
- Prior art keywords
- fatty acid
- myocardial
- sum
- range
- acid analog
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
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- 238000003745 diagnosis Methods 0.000 title description 3
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- DYIZHKNUQPHNJY-UHFFFAOYSA-N oxorhenium Chemical compound [Re]=O DYIZHKNUQPHNJY-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Fats And Perfumes (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12929899P | 1999-04-14 | 1999-04-14 | |
| US60/129,298 | 1999-04-14 | ||
| PCT/US2000/010096 WO2000061196A2 (en) | 1999-04-14 | 2000-04-14 | Fatty acid analogs for diagnosis of coronary artery disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2366789A1 CA2366789A1 (en) | 2000-10-19 |
| CA2366789C true CA2366789C (en) | 2010-09-28 |
Family
ID=22439338
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2366789A Expired - Fee Related CA2366789C (en) | 1999-04-14 | 2000-04-14 | Fatty acid analogs for diagnosis of coronary artery disease |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6437103B1 (https=) |
| EP (1) | EP1173226B1 (https=) |
| JP (1) | JP2003517457A (https=) |
| AT (1) | ATE337020T1 (https=) |
| AU (1) | AU778834B2 (https=) |
| CA (1) | CA2366789C (https=) |
| DE (1) | DE60030270T2 (https=) |
| ES (1) | ES2269131T3 (https=) |
| WO (1) | WO2000061196A2 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE526995T1 (de) * | 1995-12-01 | 2011-10-15 | Molecular Insight Pharm Inc | Stereoisomers von fettsäureanalogen für diagnostische bildgebung |
| JP4846199B2 (ja) * | 2002-03-11 | 2011-12-28 | モレキュラ インサイト ファーマシューティカルズ インコーポレイテッド | テクネチウム−ジビリジン複合体、およびその使用法 |
| EP1490114A1 (en) * | 2002-04-01 | 2004-12-29 | Biostream, Inc. | Pendant fatty acid imaging agents |
| CA2522737C (en) * | 2003-04-17 | 2017-06-06 | The General Hospital Corporation | Method for monitoring blood flow and metabolic uptake in tissue with radiolabeled alkanoic acid |
| KR100533674B1 (ko) * | 2004-02-25 | 2005-12-06 | 한국원자력연구소 | 수소화붕소 교환수지를 이용한 레늄 착물의 제조방법 |
| WO2006131803A2 (en) * | 2005-06-08 | 2006-12-14 | Ge Healthcare Limited | Method for the use of [11c] carbon monoxide in labeling synthesis of 11c-labelled esters and acids by sensitized photo-induced free radical carbonylation |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4524059A (en) | 1983-01-28 | 1985-06-18 | The General Hospital Corporation | Fatty acid analogs |
| US4615876A (en) | 1983-04-25 | 1986-10-07 | Curators Of The University Of Missouri | Macrocyclic complexes of technetium-99m for use as diagnostic radionuclides |
| US4746505A (en) * | 1985-04-26 | 1988-05-24 | President And Fellows Of Harvard College | Technetium radiodiagnostic fatty acids derived from bisamide bisthiol ligands |
| ATE526995T1 (de) | 1995-12-01 | 2011-10-15 | Molecular Insight Pharm Inc | Stereoisomers von fettsäureanalogen für diagnostische bildgebung |
-
2000
- 2000-04-14 CA CA2366789A patent/CA2366789C/en not_active Expired - Fee Related
- 2000-04-14 EP EP00922209A patent/EP1173226B1/en not_active Expired - Lifetime
- 2000-04-14 JP JP2000610528A patent/JP2003517457A/ja active Pending
- 2000-04-14 DE DE60030270T patent/DE60030270T2/de not_active Expired - Lifetime
- 2000-04-14 AT AT00922209T patent/ATE337020T1/de not_active IP Right Cessation
- 2000-04-14 ES ES00922209T patent/ES2269131T3/es not_active Expired - Lifetime
- 2000-04-14 AU AU42433/00A patent/AU778834B2/en not_active Ceased
- 2000-04-14 US US09/549,732 patent/US6437103B1/en not_active Expired - Fee Related
- 2000-04-14 WO PCT/US2000/010096 patent/WO2000061196A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| ES2269131T3 (es) | 2007-04-01 |
| US6437103B1 (en) | 2002-08-20 |
| AU4243300A (en) | 2000-11-14 |
| CA2366789A1 (en) | 2000-10-19 |
| DE60030270D1 (de) | 2006-10-05 |
| WO2000061196A3 (en) | 2001-07-26 |
| EP1173226B1 (en) | 2006-08-23 |
| WO2000061196A2 (en) | 2000-10-19 |
| AU778834B2 (en) | 2004-12-23 |
| EP1173226A2 (en) | 2002-01-23 |
| JP2003517457A (ja) | 2003-05-27 |
| ATE337020T1 (de) | 2006-09-15 |
| DE60030270T2 (de) | 2007-08-30 |
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