CA2366087A1 - Gene de la lectine du type immunoglobuline de liaison de l'acide sialique (siglec) ; proteine du type proteine de liaison de ob - Google Patents

Gene de la lectine du type immunoglobuline de liaison de l'acide sialique (siglec) ; proteine du type proteine de liaison de ob Download PDF

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Publication number
CA2366087A1
CA2366087A1 CA002366087A CA2366087A CA2366087A1 CA 2366087 A1 CA2366087 A1 CA 2366087A1 CA 002366087 A CA002366087 A CA 002366087A CA 2366087 A CA2366087 A CA 2366087A CA 2366087 A1 CA2366087 A1 CA 2366087A1
Authority
CA
Canada
Prior art keywords
protein
nucleic acid
bpl
substance
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002366087A
Other languages
English (en)
Inventor
George Foussias
George M. Yousef
Eleftherios P. Diamandis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mount Sinai Hospital Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2366087A1 publication Critical patent/CA2366087A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6445—Kallikreins (3.4.21.34; 3.4.21.35)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne des molécules d'acide nucléique, des protéines codées par ces molécules d'acide nucléique ainsi que l'utilisation de ces protéines et de ces molécules d'acide nucléique.
CA002366087A 1999-03-11 2000-03-09 Gene de la lectine du type immunoglobuline de liaison de l'acide sialique (siglec) ; proteine du type proteine de liaison de ob Abandoned CA2366087A1 (fr)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US12426099P 1999-03-11 1999-03-11
US60/124,260 1999-03-11
US12738699P 1999-04-01 1999-04-01
US60/127,386 1999-04-01
US14491999P 1999-07-21 1999-07-21
US60/144,919 1999-07-21
PCT/CA2000/000259 WO2000053747A1 (fr) 1999-03-11 2000-03-09 Gene de la lectine du type immunoglobuline de liaison de l'acide sialique (siglec) ; proteine du type proteine de liaison de ob

Publications (1)

Publication Number Publication Date
CA2366087A1 true CA2366087A1 (fr) 2000-09-14

Family

ID=27383080

Family Applications (2)

Application Number Title Priority Date Filing Date
CA002362885A Abandoned CA2362885A1 (fr) 1999-03-11 2000-03-09 Nouveaux genes humains du type kallikreine
CA002366087A Abandoned CA2366087A1 (fr) 1999-03-11 2000-03-09 Gene de la lectine du type immunoglobuline de liaison de l'acide sialique (siglec) ; proteine du type proteine de liaison de ob

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CA002362885A Abandoned CA2362885A1 (fr) 1999-03-11 2000-03-09 Nouveaux genes humains du type kallikreine

Country Status (5)

Country Link
EP (1) EP1159431A2 (fr)
JP (1) JP2002538789A (fr)
AU (2) AU3139900A (fr)
CA (2) CA2362885A1 (fr)
WO (2) WO2000053776A2 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6943236B2 (en) 1997-02-25 2005-09-13 Corixa Corporation Compositions and methods for the therapy and diagnosis of prostate cancer
EP1734051A3 (fr) * 1998-12-01 2007-09-12 Genetech, Inc. Composition et procédés de diagnostic de tumeurs
CA2360073C (fr) 1999-01-28 2011-01-18 Gen-Probe Incorporated Sondes et amorces pour la detection d'antigene prostatique specifique (psa) dans un echantillon biologique
US7034132B2 (en) 2001-06-04 2006-04-25 Anderson David W Therapeutic polypeptides, nucleic acids encoding same, and methods of use
WO2001025446A1 (fr) * 1999-10-07 2001-04-12 Schering Aktiengesellschaft Adn codant le polypeptide prost 07
JP2004512540A (ja) 2000-11-01 2004-04-22 マウント・サイナイ・ホスピタル 卵巣癌の検出
AU2002246502A1 (en) * 2000-11-17 2002-08-06 Hyseq, Inc. Nucleic acids and polypeptides
AUPR402201A0 (en) * 2001-03-27 2001-04-26 Queensland University Of Technology Polynucleotides and polypeptides linked to cancer and/or benign tumours
WO2003039475A2 (fr) * 2001-11-07 2003-05-15 Millennium Pharmaceuticals, Inc. Methodes et compositions de traitement de troubles urologiques utilisant 313, 333, 5464, 18817 ou 33524
US20060159616A1 (en) * 2002-08-28 2006-07-20 Mount Sinai Hospital Methods for detecting endocrine cancer
EP1664331A2 (fr) * 2003-08-30 2006-06-07 Bayer HealthCare AG Diagnostic et traitement de maladies associees a la kallicreine 9 (klk9)
WO2005078123A1 (fr) * 2004-02-18 2005-08-25 Bayer Healthcare Ag Diagnostic et therapeutique de maladies associees a la kallikreine 5 (klk5)
US20130315891A1 (en) * 2012-05-25 2013-11-28 Matthew Charles Formulations of human tissue kallikrein-1 for parenteral delivery and related methods
HUE032613T2 (en) 2012-06-04 2017-10-30 Diamedica Therapeutics Inc Human tissue kallikrein 1 is glycosylated isoforms
CA3011092A1 (fr) * 2016-01-12 2017-07-20 Palleon Pharmaceuticals Inc. Utilisation d'anticorps diriges contre siglec-7 ou siglec-9 dans le traitement du cancer
US11857608B2 (en) 2017-03-09 2024-01-02 Diamedica Inc. Dosage forms of tissue kallikrein 1
CN112480237B (zh) * 2019-09-12 2023-10-17 上海津曼特生物科技有限公司 一种融合蛋白及其制备方法和应用
CN114414812B (zh) * 2020-12-21 2022-09-20 华中科技大学同济医学院附属同济医院 生物标志物组合在制备暴发性心肌炎诊断试剂及暴发性心肌炎药物方面的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5786148A (en) * 1996-11-05 1998-07-28 Incyte Pharmaceuticals, Inc. Polynucleotides encoding a novel prostate-specific kallikrein
WO2000012708A2 (fr) * 1998-09-01 2000-03-09 Genentech, Inc. Nouveaux pro-polypeptides et sequences correspondantes
US6146845A (en) * 1997-04-02 2000-11-14 Smithkline Beecham Corporation Polynucleotides encoding a sialoadhesin family member-2 (SAF-2)
EP0869178A1 (fr) * 1997-04-02 1998-10-07 Smithkline Beecham Corporation SAF-3, un membre de la famille des sialoadhésines
CA2347835A1 (fr) * 1998-12-01 2000-06-08 Genentech, Inc. Promotion et inhibition de l'angiogenese et de la vascularisation cardiaque

Also Published As

Publication number Publication date
WO2000053776A2 (fr) 2000-09-14
CA2362885A1 (fr) 2000-09-14
JP2002538789A (ja) 2002-11-19
AU3139800A (en) 2000-09-28
WO2000053747A1 (fr) 2000-09-14
WO2000053776A3 (fr) 2000-12-14
AU3139900A (en) 2000-09-28
EP1159431A2 (fr) 2001-12-05

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