CA2365908A1 - Reactifs et procedes d'identification, et de modulation d'expression, du gene regule par p21 - Google Patents

Reactifs et procedes d'identification, et de modulation d'expression, du gene regule par p21 Download PDF

Info

Publication number
CA2365908A1
CA2365908A1 CA002365908A CA2365908A CA2365908A1 CA 2365908 A1 CA2365908 A1 CA 2365908A1 CA 002365908 A CA002365908 A CA 002365908A CA 2365908 A CA2365908 A CA 2365908A CA 2365908 A1 CA2365908 A1 CA 2365908A1
Authority
CA
Canada
Prior art keywords
cell
expression
gene
compound
mammalian
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002365908A
Other languages
English (en)
Inventor
Bey-Dih Chang
Igor B. Roninson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Illinois
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/449,589 external-priority patent/US6706491B1/en
Application filed by Individual filed Critical Individual
Publication of CA2365908A1 publication Critical patent/CA2365908A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4738Cell cycle regulated proteins, e.g. cyclin, CDC, INK-CCR
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • C12N5/12Fused cells, e.g. hybridomas
    • C12N5/16Animal cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne des procédés et réactifs d'identification de gènes impliqués dans la progression du cycle cellulaire, le développement de la croissance, la modulation de l'apoptose, la sénescence et le vieillissement des cellules; elle concerne également des procédés d'identification de composés inhibant ou potentialisant la sénescence des cellules régulée par p21.
CA002365908A 1999-04-09 2000-04-07 Reactifs et procedes d'identification, et de modulation d'expression, du gene regule par p21 Abandoned CA2365908A1 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US12867699P 1999-04-09 1999-04-09
US60/128,676 1999-04-09
US09/449,589 US6706491B1 (en) 1999-04-09 1999-11-29 Reagents and methods for identifying and modulating expression of genes regulated by p21
US09/449,589 1999-11-29
PCT/US2000/009286 WO2000061751A1 (fr) 1999-04-09 2000-04-07 REACTIFS ET PROCEDES D'IDENTIFICATION, ET DE MODULATION D'EXPRESSION, DU GENE REGULE PAR p21

Publications (1)

Publication Number Publication Date
CA2365908A1 true CA2365908A1 (fr) 2000-10-19

Family

ID=26826820

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002365908A Abandoned CA2365908A1 (fr) 1999-04-09 2000-04-07 Reactifs et procedes d'identification, et de modulation d'expression, du gene regule par p21

Country Status (5)

Country Link
EP (1) EP1169443A1 (fr)
JP (3) JP2003521238A (fr)
KR (1) KR20020013523A (fr)
AU (1) AU4079000A (fr)
CA (1) CA2365908A1 (fr)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6706491B1 (en) * 1999-04-09 2004-03-16 The Board Of Trustees Of The University Of Illinois Reagents and methods for identifying and modulating expression of genes regulated by p21

Also Published As

Publication number Publication date
AU4079000A (en) 2000-11-14
JP2006238884A (ja) 2006-09-14
EP1169443A1 (fr) 2002-01-09
JP2006340722A (ja) 2006-12-21
JP2003521238A (ja) 2003-07-15
KR20020013523A (ko) 2002-02-20

Similar Documents

Publication Publication Date Title
US6706491B1 (en) Reagents and methods for identifying and modulating expression of genes regulated by p21
US20090208935A1 (en) Reagents and methods for identifying and modulating expression of tumor senescence genes
JP2004530422A (ja) 急速なアポトーシスを誘導するjfy1蛋白質
JP2009077705A (ja) Cdk阻害剤によって調節される遺伝子発現を同定及び調節するための試薬及び方法
AU2002248262A1 (en) Reagents and methods for identifying and modulating expression of tumor senescence genes
JP2009077714A (ja) 腫瘍老化遺伝子の発現を同定および調節するための試薬および方法
EP1527171A2 (fr) Reactifs et methodes d'identification et de modulation de l'expression genique regulee par les inhibiteurs de la cdk
AU2004202327B2 (en) Reagents and Methods for Identifying and Modulating Expression of Genes Regulated by p21
Ahmed et al. Gene expression profile of the rat eye iridocorneal angle: NEIBank expressed sequence tag analysis
CA2365908A1 (fr) Reactifs et procedes d'identification, et de modulation d'expression, du gene regule par p21
AU2006200921A1 (en) Reagents and methods for identifying and modulating expression of genes regulated by CDK inhibitors
WO2004048520A2 (fr) Redd1, une cible transcriptionnelle de p63 et p53, et ses procedes d'utilisation
AU2002251842A1 (en) Reagents and methods for identifying and modulating expression of genes regulated by CDK inhibitors
AU2008200727A1 (en) Reagents and methods for identifying and modulating expression of genes regulated by CDK inhibitors

Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued