CA2365460A1 - Copolymeres fluores pour revetement de dispositifs biomedicaux et procede de fabrication correspondant - Google Patents
Copolymeres fluores pour revetement de dispositifs biomedicaux et procede de fabrication correspondant Download PDFInfo
- Publication number
- CA2365460A1 CA2365460A1 CA002365460A CA2365460A CA2365460A1 CA 2365460 A1 CA2365460 A1 CA 2365460A1 CA 002365460 A CA002365460 A CA 002365460A CA 2365460 A CA2365460 A CA 2365460A CA 2365460 A1 CA2365460 A1 CA 2365460A1
- Authority
- CA
- Canada
- Prior art keywords
- comonomer
- fluorinated
- copolymer
- formula
- moieties derived
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
- C09D153/00—Coating compositions based on block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Coating compositions based on derivatives of such polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/08—Materials for coatings
- A61L29/085—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L29/00—Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
- A61L29/14—Materials characterised by their function or physical properties, e.g. lubricating compositions
- A61L29/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/10—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
- C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
- C08F220/10—Esters
- C08F220/22—Esters containing halogen
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F293/00—Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule
- C08F293/005—Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule using free radical "living" or "controlled" polymerisation, e.g. using a complexing agent
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F297/00—Macromolecular compounds obtained by successively polymerising different monomer systems using a catalyst of the ionic or coordination type without deactivating the intermediate polymer
- C08F297/02—Macromolecular compounds obtained by successively polymerising different monomer systems using a catalyst of the ionic or coordination type without deactivating the intermediate polymer using a catalyst of the anionic type
- C08F297/026—Macromolecular compounds obtained by successively polymerising different monomer systems using a catalyst of the ionic or coordination type without deactivating the intermediate polymer using a catalyst of the anionic type polymerising acrylic acid, methacrylic acid or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L53/00—Compositions of block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/606—Coatings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Transplantation (AREA)
- Dermatology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Surgery (AREA)
- Vascular Medicine (AREA)
- Materials Engineering (AREA)
- Wood Science & Technology (AREA)
- Inorganic Chemistry (AREA)
- Materials For Medical Uses (AREA)
Abstract
La présente invention concerne des copolymères dont des premiers fragments sont dérivés d'au moins un premier comonomère fluoré représenté par la formule générale (I). Dans cette formule, X est hydrogène ou méthyle, Y est une liaison simple ou un radical représenté par la formule CH¿2?NRSO¿2? ou NRSO¿2?, dans laquelle R est un groupe alkyle en C¿1?-C¿6?, Z est hydrogène ou fluor, et n vaut de 0 à 12. D'autres fragments de ces copolymères sont dérivés d'au moins un second copolymère non fluoré. En l'occurrence, la température de transition vitreuse de l'homopolymère du second comonomère est inférieure à la température de tansition vitreuse de l'homopolymère du premier comonomère. Une couche d'un tel copolymère, comprenant en outre éventuellement une quantité biologiquement efficace d'au moins un ingrédient biologiquement actif, convient particulièrement au revêtement d'un dispositif biomédical tel qu'un cathéter ou un stent.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP99870063 | 1999-03-31 | ||
EP99870063.7 | 1999-03-31 | ||
PCT/EP2000/002733 WO2000059963A1 (fr) | 1999-03-31 | 2000-03-29 | Copolymeres fluores pour revetement de dispositifs biomedicaux et procede de fabrication correspondant |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2365460A1 true CA2365460A1 (fr) | 2000-10-12 |
Family
ID=8243815
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002365460A Abandoned CA2365460A1 (fr) | 1999-03-31 | 2000-03-29 | Copolymeres fluores pour revetement de dispositifs biomedicaux et procede de fabrication correspondant |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP1171490A1 (fr) |
AU (1) | AU4112600A (fr) |
CA (1) | CA2365460A1 (fr) |
WO (1) | WO2000059963A1 (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009043174A1 (fr) * | 2007-10-05 | 2009-04-09 | Interface Biologics Inc. | Polymères réticulés oligofluorés et leurs utilisations |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030195610A1 (en) | 2002-04-04 | 2003-10-16 | Herrmann Robert A. | Processes for producing polymer coatings through surface polymerization |
US7041308B2 (en) | 2002-04-18 | 2006-05-09 | Poly-Med, Inc. | Drug-polymer coated stents with segmented homochain copolyesters |
US7261946B2 (en) | 2003-11-14 | 2007-08-28 | Advanced Cardiovascular Systems, Inc. | Block copolymers of acrylates and methacrylates with fluoroalkenes |
DE102004025130A1 (de) * | 2004-05-18 | 2005-12-08 | Universitätsklinikum Hamburg-Eppendorf Körperschaft des Öffentlichen Rechts | Verfahren und Vorrichtung zur Untersuchung von Sludgeablagerungen auf Materialien für Endoprothesen sowie Endoprothese |
US8034874B2 (en) * | 2005-11-23 | 2011-10-11 | Boston Scientific Scimed, Inc. | Medical devices having polymeric regions that contain fluorocarbon-containing block copolymers |
EP2468305B1 (fr) * | 2010-12-03 | 2016-06-15 | Xeltis B.V. | Utilisation d'un polymère fluoré en tant qu'agent de contraste dans une imagerie à résonnance magnétique (IRM) 19F à l'état solide, support comprenant ce polymère et utilisation associée |
US10238776B2 (en) | 2010-12-29 | 2019-03-26 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Hydrophobic catheter and composition |
US9913933B2 (en) | 2013-03-15 | 2018-03-13 | St. Jude Medical, Cardiology Division, Inc. | Multilayered catheter shaft containing polyvinylidene fluoride polymers |
KR102128282B1 (ko) * | 2014-01-09 | 2020-06-30 | 삼성전자주식회사 | 항균방오 코팅 조성물, 그 피막, 그 제조 방법 및 그 코팅이 적용된 제품 |
EP3357946A1 (fr) * | 2017-02-07 | 2018-08-08 | Daikin Industries, Ltd. | Composition de résine hydrofuge et oléofuge |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4663409A (en) * | 1984-12-24 | 1987-05-05 | Bausch & Lomb Incorporated | Alpha, beta-unsaturated carbonyl modified amino acid monomer and polymers for biomedical uses |
US4931279A (en) * | 1985-08-16 | 1990-06-05 | Bausch & Lomb Incorporated | Sustained release formulation containing an ion-exchange resin |
JPH0539444A (ja) * | 1990-11-30 | 1993-02-19 | Hitachi Chem Co Ltd | ポジ型感光性アニオン電着塗料樹脂組成物、これを用いた電着塗装浴、電着塗装法及びプリント回路板の製造方法 |
US5212229A (en) * | 1991-03-28 | 1993-05-18 | Union Carbide Chemicals & Plastics Technology Corporation | Monodispersed acrylic polymers in supercritical, near supercritical and subcritical fluids |
FR2725721B1 (fr) * | 1994-10-18 | 1998-12-04 | Atochem Elf Sa | Latex et melanges de latex acryliques et methacyliques fluores, leurs procedes de fabrication et leurs applications dans le domaine des revetements hydrophobes |
-
2000
- 2000-03-29 EP EP00920607A patent/EP1171490A1/fr not_active Withdrawn
- 2000-03-29 AU AU41126/00A patent/AU4112600A/en not_active Abandoned
- 2000-03-29 WO PCT/EP2000/002733 patent/WO2000059963A1/fr not_active Application Discontinuation
- 2000-03-29 CA CA002365460A patent/CA2365460A1/fr not_active Abandoned
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2009043174A1 (fr) * | 2007-10-05 | 2009-04-09 | Interface Biologics Inc. | Polymères réticulés oligofluorés et leurs utilisations |
US10039864B2 (en) | 2007-10-05 | 2018-08-07 | Interface Biologics, Inc. | Oligofluorinated cross-linked polymers and uses thereof |
Also Published As
Publication number | Publication date |
---|---|
AU4112600A (en) | 2000-10-23 |
EP1171490A1 (fr) | 2002-01-16 |
WO2000059963A1 (fr) | 2000-10-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Discontinued |