CA2358567A1 - Adhesif tissulaire permettant de traiter des surfaces saignant abondamment - Google Patents

Adhesif tissulaire permettant de traiter des surfaces saignant abondamment Download PDF

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Publication number
CA2358567A1
CA2358567A1 CA002358567A CA2358567A CA2358567A1 CA 2358567 A1 CA2358567 A1 CA 2358567A1 CA 002358567 A CA002358567 A CA 002358567A CA 2358567 A CA2358567 A CA 2358567A CA 2358567 A1 CA2358567 A1 CA 2358567A1
Authority
CA
Canada
Prior art keywords
adhesive
collagen
albumin
tissue
tissue adhesive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002358567A
Other languages
English (en)
Inventor
David A. Browdie
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2358567A1 publication Critical patent/CA2358567A1/fr
Abandoned legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
    • A61L24/043—Mixtures of macromolecular materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Materials For Medical Uses (AREA)

Abstract

L'invention concerne une nouvelle technologie d'adhésif tissulaire consistant en une combinaison de protéines traitées par ultrasons et comprenant du collagène et de l'albumine formant une matière visqueuse qui développe des propriétés adhésives lorsqu'elle est réticulée chimiquement. L'invention concerne également un nouvel agent de réticulation développée en association avec ledit adhésif tissulaire et doté de propriétés étonnamment stables obtenu en faisant réagir du glutaraldéhyde avec des peptides ou des acides aminés et en laissant cette réaction arriver à terme. On mélange ensuite cet agent de réticulation chimique à ces protéines traitées par ultrasons, on le fait réagir pendant une durée prédéterminée, puis on l'utilise pour fermer hermétiquement de larges surfaces de tissus saignant abondamment, y compris notamment le foie, les poumons et les systèmes vasculaires majeurs, chez des sujets souffrant ou ne souffrant pas des troubles de saignement. Il a été avéré que ledit adhésif tissulaire convient pour fermer des sites de suture et permet d'empêcher toute fuite.
CA002358567A 1999-01-08 1999-01-08 Adhesif tissulaire permettant de traiter des surfaces saignant abondamment Abandoned CA2358567A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1999/000504 WO2000040277A1 (fr) 1999-01-08 1999-01-08 Adhesif tissulaire permettant de traiter des surfaces saignant abondamment

Publications (1)

Publication Number Publication Date
CA2358567A1 true CA2358567A1 (fr) 2000-07-13

Family

ID=22271962

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002358567A Abandoned CA2358567A1 (fr) 1999-01-08 1999-01-08 Adhesif tissulaire permettant de traiter des surfaces saignant abondamment

Country Status (4)

Country Link
EP (1) EP1140233A1 (fr)
AU (1) AU2314799A (fr)
CA (1) CA2358567A1 (fr)
WO (1) WO2000040277A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7129210B2 (en) * 2003-07-23 2006-10-31 Covalent Medical, Inc. Tissue adhesive sealant
GB0420888D0 (en) 2004-09-20 2004-10-20 Photopharmica Ltd Compounds and uses
WO2010146582A2 (fr) 2009-06-15 2010-12-23 Technion- Research And Development Foundation Ltd. Adhésifs chirurgicaux renforcés et colles et leur application in situ
CN113876997B (zh) * 2021-09-27 2022-09-20 广东省科学院健康医学研究所 一种白蛋白复合粘合剂及其制备方法
WO2023191176A1 (fr) * 2022-03-28 2023-10-05 주식회사 덴하우스 Composition de régénération osseuse et forme galénique
CN117860953A (zh) * 2023-02-03 2024-04-12 福建吉特瑞生物科技有限公司 一种组织粘合剂及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5292362A (en) * 1990-07-27 1994-03-08 The Trustees Of Columbia University In The City Of New York Tissue bonding and sealing composition and method of using the same
US5859077A (en) * 1995-12-19 1999-01-12 Nova-Sorb Ltd. Novel Absorbents Apparatus and method for producing porous superabsorbent materials

Also Published As

Publication number Publication date
WO2000040277A1 (fr) 2000-07-13
EP1140233A1 (fr) 2001-10-10
AU2314799A (en) 2000-07-24

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Legal Events

Date Code Title Description
FZDE Discontinued