CA2356442C - Nmr spectroscopic in vitro assay using hyperpolarization - Google Patents
Nmr spectroscopic in vitro assay using hyperpolarization Download PDFInfo
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- CA2356442C CA2356442C CA002356442A CA2356442A CA2356442C CA 2356442 C CA2356442 C CA 2356442C CA 002356442 A CA002356442 A CA 002356442A CA 2356442 A CA2356442 A CA 2356442A CA 2356442 C CA2356442 C CA 2356442C
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
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- Medicinal Chemistry (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (5)
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| GB9828852.5 | 1998-12-30 | ||
| GBGB9828852.5A GB9828852D0 (en) | 1998-12-30 | 1998-12-30 | Nmr spectroscopy method |
| GBGB9918096.0A GB9918096D0 (en) | 1999-08-02 | 1999-08-02 | NMR Spectroscopy method |
| GB9918096.0 | 1999-08-02 | ||
| PCT/GB1999/004410 WO2000040988A1 (en) | 1998-12-30 | 1999-12-23 | Nmr spectroscopic in vitro assay using hyperpolarization |
Publications (2)
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| CA2356442A1 CA2356442A1 (en) | 2000-07-13 |
| CA2356442C true CA2356442C (en) | 2009-03-24 |
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| CA002356442A Expired - Fee Related CA2356442C (en) | 1998-12-30 | 1999-12-23 | Nmr spectroscopic in vitro assay using hyperpolarization |
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| US (1) | US7501236B1 (enExample) |
| EP (1) | EP1141738A1 (enExample) |
| JP (1) | JP2002534687A (enExample) |
| AU (1) | AU766923B2 (enExample) |
| CA (1) | CA2356442C (enExample) |
| IL (2) | IL143927A0 (enExample) |
| WO (1) | WO2000040988A1 (enExample) |
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| GB9911681D0 (en) * | 1999-05-19 | 1999-07-21 | Nycomed Imaging As | Process |
| GB0014463D0 (en) | 2000-06-14 | 2000-08-09 | Nycomed Amersham Plc | NMR Method |
| GB0022341D0 (en) | 2000-09-12 | 2000-10-25 | Nycomed Imaging As | Method |
| NO20023357D0 (no) * | 2002-04-19 | 2002-07-11 | Amersham Health As | Blanding |
| NO20023358D0 (no) * | 2002-04-19 | 2002-07-11 | Amersham Health As | Metode |
| GB0219953D0 (en) * | 2002-08-29 | 2002-10-02 | Amersham Health R & D Ab | An arrangement and a method for providing contrast agents |
| NO20025738D0 (no) * | 2002-11-29 | 2002-11-29 | Amersham Health As | Metode |
| GB0308586D0 (en) | 2003-04-14 | 2003-05-21 | Amersham Health R & D Ab | Method and arrangements in NMR spectroscopy |
| NO20035626D0 (no) * | 2003-12-17 | 2003-12-17 | Amersham Health As | Metode |
| EP1555538A1 (en) * | 2004-01-15 | 2005-07-20 | Bruker BioSpin MRI GmbH | Method of fast multidimensional NMR spectroscopy |
| US20100233096A1 (en) * | 2006-03-29 | 2010-09-16 | Lerche Mathilde H | Method to produce hyperpolarised carboxylates and sulphonates |
| EP2117607A4 (en) * | 2007-01-11 | 2012-08-08 | Huntington Medical Res Inst | PICTURES AND METHOD FOR THEIR USE |
| US20100233089A1 (en) * | 2007-10-05 | 2010-09-16 | Huntington Medical Research Institutes | Imaging of genetic material with magnetic resonance |
| EP2902041A1 (en) * | 2007-12-19 | 2015-08-05 | GE Healthcare Limited | Composition and method for generating a metabolic profile using 13C-MR detection |
| WO2009129265A1 (en) * | 2008-04-14 | 2009-10-22 | Huntington Medical Research Institutes | Methods and apparatus for pasadena hyperpolarization |
| US9678185B2 (en) | 2013-03-15 | 2017-06-13 | Pepsico, Inc. | Method and apparatus for measuring physico-chemical properties using a nuclear magnetic resonance spectrometer |
| US10338052B2 (en) | 2015-11-30 | 2019-07-02 | Vanderbilt University | Methods of detecting sulfur-containing compounds |
| US20180230182A1 (en) * | 2017-02-15 | 2018-08-16 | Cedars-Sinai Medical Center | Hyperpolarization of amino acid residues for producing hyperpolarized peptides |
| DE102018203434B4 (de) * | 2018-03-07 | 2019-12-05 | Bernd Willi Karl-Heinz Diehl | Verfahren zur heteronuklearen quantitativen Bestimmung mittels NMR-Spektroskopie, Referenzsubstanzen hierfür und Verfahren zur Bestimmung des Deuterierungsgrades einer deuterierten Verbindung |
| WO2022238350A1 (en) | 2021-05-11 | 2022-11-17 | Ecole Polytechnique Federale De Lausanne (Epfl) | Dnp biosensor |
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| US5834226A (en) * | 1991-01-31 | 1998-11-10 | Xytronyx, Inc. | One-step test for aspartate aminotransferase |
| US5393669A (en) * | 1993-02-05 | 1995-02-28 | Martek Biosciences Corp. | Compositions and methods for protein structural determinations |
| US6103492A (en) * | 1993-03-08 | 2000-08-15 | Indiana University | Polynucleotide encoding mu opioid receptor |
| US5475304A (en) | 1993-10-01 | 1995-12-12 | The United States Of America As Represented By The Secretary Of The Navy | Magnetoresistive linear displacement sensor, angular displacement sensor, and variable resistor using a moving domain wall |
| US5545396A (en) | 1994-04-08 | 1996-08-13 | The Research Foundation Of State University Of New York | Magnetic resonance imaging using hyperpolarized noble gases |
| US5479925A (en) | 1994-06-23 | 1996-01-02 | General Electric Company | Magnetic resonance (MR) angiography in a low-field imaging magnet |
| US5698401A (en) * | 1995-11-14 | 1997-12-16 | Abbott Laboratories | Use of nuclear magnetic resonance to identify ligands to target biomolecules |
| EP0904542B1 (en) * | 1996-03-01 | 2005-06-29 | Beckman Coulter, Inc. | System for simultaneously conducting multiple ligand binding assays |
| FI982069A7 (fi) * | 1996-03-29 | 1998-11-10 | Lawrence Berkeley Nat Laboratory | NMR:n ja MRI:n tehostaminen hyperpolaroitujen jalokaasujen läsnä olles sa |
| US6043024A (en) * | 1997-04-18 | 2000-03-28 | Abbott Laboratories | Use of one-dimensional nuclear magnetic resonance to identify ligands to target biomolecules |
| US6278893B1 (en) * | 1998-01-05 | 2001-08-21 | Nycomed Imaging As | Method of magnetic resonance imaging of a sample with ex vivo polarization of an MR imaging agent |
| US6574496B1 (en) * | 1999-05-19 | 2003-06-03 | Amersham Health As | Magnetic resonance imaging |
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- 1999-12-23 AU AU18803/00A patent/AU766923B2/en not_active Ceased
- 1999-12-23 WO PCT/GB1999/004410 patent/WO2000040988A1/en not_active Ceased
- 1999-12-23 CA CA002356442A patent/CA2356442C/en not_active Expired - Fee Related
- 1999-12-23 US US09/869,629 patent/US7501236B1/en not_active Expired - Fee Related
- 1999-12-23 EP EP99962446A patent/EP1141738A1/en not_active Ceased
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Also Published As
| Publication number | Publication date |
|---|---|
| EP1141738A1 (en) | 2001-10-10 |
| JP2002534687A (ja) | 2002-10-15 |
| IL143927A0 (en) | 2002-04-21 |
| WO2000040988A1 (en) | 2000-07-13 |
| AU1880300A (en) | 2000-07-24 |
| IL143927A (en) | 2007-05-15 |
| US7501236B1 (en) | 2009-03-10 |
| AU766923B2 (en) | 2003-10-23 |
| CA2356442A1 (en) | 2000-07-13 |
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