CA2353616A1 - Assays for compounds which increase phospholipase a2 activity - Google Patents
Assays for compounds which increase phospholipase a2 activity Download PDFInfo
- Publication number
- CA2353616A1 CA2353616A1 CA002353616A CA2353616A CA2353616A1 CA 2353616 A1 CA2353616 A1 CA 2353616A1 CA 002353616 A CA002353616 A CA 002353616A CA 2353616 A CA2353616 A CA 2353616A CA 2353616 A1 CA2353616 A1 CA 2353616A1
- Authority
- CA
- Canada
- Prior art keywords
- compound
- phospholipase
- docosahexaenoic acid
- expression
- dha
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/44—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/743—Steroid hormones
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
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- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
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- Public Health (AREA)
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- Neurosurgery (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
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- Chemical Kinetics & Catalysis (AREA)
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- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Psychiatry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- General Engineering & Computer Science (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9826899.8A GB9826899D0 (en) | 1998-12-08 | 1998-12-08 | Methods to treat depression and other psychiatric disorders and assays for compounds |
GB9826899.8 | 1998-12-08 | ||
PCT/EP1999/009546 WO2000034791A1 (en) | 1998-12-08 | 1999-12-07 | Assays for compounds which increase phospholipase a2 activity |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2353616A1 true CA2353616A1 (en) | 2000-06-15 |
Family
ID=10843783
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002353616A Abandoned CA2353616A1 (en) | 1998-12-08 | 1999-12-07 | Assays for compounds which increase phospholipase a2 activity |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1137949A1 (ja) |
JP (1) | JP2002532687A (ja) |
AU (1) | AU1971200A (ja) |
CA (1) | CA2353616A1 (ja) |
GB (1) | GB9826899D0 (ja) |
WO (1) | WO2000034791A1 (ja) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0001703D0 (en) * | 2000-01-25 | 2000-03-15 | Glaxo Group Ltd | Assay |
KR20030046896A (ko) * | 2001-12-07 | 2003-06-18 | 학교법인 포항공과대학교 | 당질코르티코이드에 의해 발현이 조절되는 재조합 리포터유전자를 가지는 형질전환 세포주 및 이를 이용한당질코르티코이드 유사물질 및 저해물질의 생물학적검색방법 |
WO2003071271A1 (fr) * | 2002-02-21 | 2003-08-28 | Tokyo Gas Company Limited | Agents de tests pour evaluer l'effet pharmacologique de medicaments, et procede et reactifs pour selectionner des medicaments ayant un excellent effet d'administration et/ou peu d'effets secondaires parmi des medicaments avec enzymes, inhibiteurs d'enzymes ou ligands de recepteurs et/ou promedicaments de ceux-ci |
CN104777314B (zh) * | 2009-08-12 | 2017-01-04 | 福满代谢组技术有限公司 | 抑郁症的生物标记物、抑郁症的生物标记物的测定方法、计算机程序及记录介质 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9224809D0 (en) * | 1992-11-26 | 1993-01-13 | Scotia Holdings Plc | Schizophrenia |
US5464754A (en) * | 1993-08-17 | 1995-11-07 | The Regents Of The University Of California | Assay and substrate for arachidonoyl-specific phospholipase A2 |
-
1998
- 1998-12-08 GB GBGB9826899.8A patent/GB9826899D0/en not_active Ceased
-
1999
- 1999-12-07 EP EP99963400A patent/EP1137949A1/en not_active Withdrawn
- 1999-12-07 AU AU19712/00A patent/AU1971200A/en not_active Abandoned
- 1999-12-07 CA CA002353616A patent/CA2353616A1/en not_active Abandoned
- 1999-12-07 JP JP2000587194A patent/JP2002532687A/ja active Pending
- 1999-12-07 WO PCT/EP1999/009546 patent/WO2000034791A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2000034791A1 (en) | 2000-06-15 |
EP1137949A1 (en) | 2001-10-04 |
AU1971200A (en) | 2000-06-26 |
JP2002532687A (ja) | 2002-10-02 |
GB9826899D0 (en) | 1999-01-27 |
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