CA2353531A1 - Nitric oxide-producing hydrogel materials - Google Patents

Nitric oxide-producing hydrogel materials Download PDF

Info

Publication number
CA2353531A1
CA2353531A1 CA002353531A CA2353531A CA2353531A1 CA 2353531 A1 CA2353531 A1 CA 2353531A1 CA 002353531 A CA002353531 A CA 002353531A CA 2353531 A CA2353531 A CA 2353531A CA 2353531 A1 CA2353531 A1 CA 2353531A1
Authority
CA
Canada
Prior art keywords
macromer
regions
region
tissue
macromer composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002353531A
Other languages
English (en)
French (fr)
Inventor
Jennifer L. West
Kristyn Simcha Masters
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
William Marsh Rice University
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2353531A1 publication Critical patent/CA2353531A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6903—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being semi-solid, e.g. an ointment, a gel, a hydrogel or a solidifying gel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Colloid Chemistry (AREA)
CA002353531A 1999-09-02 2000-09-01 Nitric oxide-producing hydrogel materials Abandoned CA2353531A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15205499P 1999-09-02 1999-09-02
US60/152,054 1999-09-02
PCT/US2000/024058 WO2001015738A2 (en) 1999-09-02 2000-09-01 Nitric oxide-producing hydrogel materials

Publications (1)

Publication Number Publication Date
CA2353531A1 true CA2353531A1 (en) 2001-03-08

Family

ID=22541347

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002353531A Abandoned CA2353531A1 (en) 1999-09-02 2000-09-01 Nitric oxide-producing hydrogel materials

Country Status (7)

Country Link
EP (1) EP1194171A2 (es)
AU (1) AU7101600A (es)
CA (1) CA2353531A1 (es)
CZ (1) CZ20011899A3 (es)
IL (1) IL143305A0 (es)
MX (1) MXPA01005338A (es)
WO (1) WO2001015738A2 (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7279176B1 (en) 1999-09-02 2007-10-09 Rice University Nitric oxide-producing hydrogel materials
US7052711B2 (en) 1999-09-02 2006-05-30 Rice University Nitric oxide-producing hydrogel materials
US20020013261A1 (en) * 2000-05-18 2002-01-31 Robert Pawliuk Methods and compositions for promoting angiogenesis using polyethylene glycol (PEG) polymers
JP4841066B2 (ja) * 2000-09-01 2011-12-21 ライスユニバーシティ 酸化窒素生成ヒドロゲル物質
US8066904B2 (en) 2001-09-05 2011-11-29 Geno Llc Controlled generation of nitric oxide
US7084115B2 (en) 2002-04-29 2006-08-01 Oxyplus, Inc. Inositol pyrophosphates, and methods of use thereof
AU2003273272A1 (en) * 2002-06-03 2003-12-19 Alinis Biosciences, Inc. Therapeutic agent-containing polymeric nanoarticles
US7618594B2 (en) 2004-08-18 2009-11-17 Geno Llc Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
CA2576957C (en) 2004-08-18 2013-04-02 Geno Llc Conversion of nitrogen dioxide (no2) to nitric oxide (no)
CA2606565C (en) 2005-05-27 2016-05-10 The University Of North Carolina At Chapel Hill Nitric oxide-releasing particles for nitric oxide therapeutics and biomedical applications
AU2008232413B2 (en) 2007-03-23 2013-09-19 VERO Biotech LLC. Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
EP2247381B1 (en) 2008-01-28 2016-11-30 Geno LLC Conversion of nitrogen dioxide (no2) to nitric oxide (no)
US8607785B2 (en) 2008-08-21 2013-12-17 Geno Llc Systems and devices for generating nitric oxide
AU2010263098B2 (en) 2009-06-22 2016-01-07 VERO Biotech LLC. Nitric oxide therapies
ES2958410T3 (es) 2009-08-21 2024-02-08 Novan Inc Geles tópicos
CN102695528B (zh) 2009-08-21 2016-07-13 诺万公司 创伤敷料、其使用方法及其形成方法
EP2501427B1 (en) 2009-11-20 2018-03-21 Geno LLC Nitric oxide delivery system
US8591876B2 (en) 2010-12-15 2013-11-26 Novan, Inc. Methods of decreasing sebum production in the skin
WO2012118819A2 (en) 2011-02-28 2012-09-07 Novan, Inc. Nitric oxide-releasing s-nitrosothiol-modified silica particles and methods of making the same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5691423A (en) * 1992-08-24 1997-11-25 The United States Of America As Represented By The Department Of Health And Human Services Polysaccharide-bound nitric oxide-nucleophile adducts
US5910316A (en) * 1992-08-24 1999-06-08 The United States Of America, As Represented By The Department Of Health And Human Services Use of nitric oxide-releasing agents to treat impotency
US5797887A (en) * 1996-08-27 1998-08-25 Novovasc Llc Medical device with a surface adapted for exposure to a blood stream which is coated with a polymer containing a nitrosyl-containing organo-metallic compound which releases nitric oxide from the coating to mediate platelet aggregation
HUP9801673A1 (hu) * 1998-07-24 2000-08-28 CYCLOLAB, Ciklodextrin Kutató-Fejlesztő Kft. Helyi vérbőséget fokozó gyógyszerkészítmények előállítása és alkalmazása

Also Published As

Publication number Publication date
WO2001015738A3 (en) 2002-01-31
CZ20011899A3 (cs) 2001-11-14
WO2001015738A2 (en) 2001-03-08
IL143305A0 (en) 2002-04-21
AU7101600A (en) 2001-03-26
EP1194171A2 (en) 2002-04-10
MXPA01005338A (es) 2003-07-14

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued