CA2352592C - Composes quinazolinone - Google Patents

Composes quinazolinone Download PDF

Info

Publication number
CA2352592C
CA2352592C CA002352592A CA2352592A CA2352592C CA 2352592 C CA2352592 C CA 2352592C CA 002352592 A CA002352592 A CA 002352592A CA 2352592 A CA2352592 A CA 2352592A CA 2352592 C CA2352592 C CA 2352592C
Authority
CA
Canada
Prior art keywords
compound
alkyl
parp
compounds
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002352592A
Other languages
English (en)
Other versions
CA2352592A1 (fr
Inventor
Roger John Griffin
Alan Hilary Calvert
Nicola Jane Curtin
David Richard Newell
Bernard Thomas Golding
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Newcastle University Ventures Ltd
Original Assignee
Newcastle University Ventures Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9404485A external-priority patent/GB9404485D0/en
Application filed by Newcastle University Ventures Ltd filed Critical Newcastle University Ventures Ltd
Publication of CA2352592A1 publication Critical patent/CA2352592A1/fr
Application granted granted Critical
Publication of CA2352592C publication Critical patent/CA2352592C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CA002352592A 1994-03-09 1995-03-09 Composes quinazolinone Expired - Fee Related CA2352592C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9404485A GB9404485D0 (en) 1994-03-09 1994-03-09 Benzamide analogues
GB9404485.6 1994-03-09
CA002184747A CA2184747C (fr) 1994-03-09 1995-03-09 Analogues de benzamide, utiles comme inhibiteurs de l'enzyme parp (adp-ribosyltransferase, adprt), reparatrice de l'adn

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA002184747A Division CA2184747C (fr) 1994-03-09 1995-03-09 Analogues de benzamide, utiles comme inhibiteurs de l'enzyme parp (adp-ribosyltransferase, adprt), reparatrice de l'adn

Publications (2)

Publication Number Publication Date
CA2352592A1 CA2352592A1 (fr) 1995-09-14
CA2352592C true CA2352592C (fr) 2006-06-06

Family

ID=25678653

Family Applications (2)

Application Number Title Priority Date Filing Date
CA002352592A Expired - Fee Related CA2352592C (fr) 1994-03-09 1995-03-09 Composes quinazolinone
CA002350941A Abandoned CA2350941A1 (fr) 1994-03-09 1995-03-09 Analogues de benzamide comme inhibiteurs de l'enzyme parp reparatrice de l'adn

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA002350941A Abandoned CA2350941A1 (fr) 1994-03-09 1995-03-09 Analogues de benzamide comme inhibiteurs de l'enzyme parp reparatrice de l'adn

Country Status (1)

Country Link
CA (2) CA2352592C (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012151701A1 (fr) * 2011-05-10 2012-11-15 Université Laval / Vice-Rectorat À La Recherche Et À La Création Procédés pour le traitement et le diagnostic de l'hypertension artérielle pulmonaire

Also Published As

Publication number Publication date
CA2350941A1 (fr) 1995-09-14
CA2352592A1 (fr) 1995-09-14

Similar Documents

Publication Publication Date Title
EP0897915B1 (fr) Composes quinazoliniques comme agents chemotherapeutiques
US6100283A (en) Benzimidazole compounds
RU2671847C2 (ru) Производные 2,3-дигидро-изоиндол-1-она и способы их применения в качестве ингибиторов тирозинкиназы брутона
JPS62265272A (ja) 新規置換2、4−ジアミノ−5−ベンジルピリミジン類、その製法およびそれを含有する抗菌剤
Chan et al. Synthesis, biological evaluation, and quantitative structure-activity relationship analysis of 2-hydroxy-1H-isoindolediones as new cytostatic agents
CN113264949B (zh) 一类螺苯并噁嗪哌啶α,β-不饱和酮类衍生物的设计合成与应用
CA2352592C (fr) Composes quinazolinone
CN112679409B (zh) 一种4-吲哚-取代硫半脲衍生物及其制备方法和应用
Basavarajaiah et al. Synthesis and anti-microbial activity of (Z)-4-(4-substituted-thiazol-2-yl)-1-(2-oxoindolin-3-ylidene) semicarbazide and its derivatives
Panwar et al. Synthesis, characterization and biological activity of some substituted pyrazolyl and pyrazolinyl-1, 3, 4-thiadiazino (6, 5-b) indoles
JPH0733743A (ja) 2−アリール−4−キノリノール誘導体
Sarode et al. Synthesis, Characterization of 2-Methylthio-1, 4-dihydropyrimidines for its Antibacterial potential
Kareem et al. Synthesis, Characterization and Antibacterial Evaluation of Some New Heterocyclic Compounds Derived from 2-(1, 1-Dimethyl-1, 3-Dihydro-2H-Benzo [e] Indol-2-Ylidene) Malonaldehyde
Wang et al. Design, synthesis and antitumor activity of 2-substituted quinazoline-4-amine derivatives
Sonker et al. SYNTHESIS AND BIOLOGICAL EVALUATION OF 1, 3, 5-TRISUBSTITUTED PYRAZOLINES AS ANTIMALARIAL-ANTIMICROBIAL AGENTS.
CN115109050A (zh) 一种基于喹唑啉酮的1,3,4-噁二唑类化合物的制备方法和应用
CN111205303A (zh) 噻吩并[2,3-d]嘧啶基异羟肟酸衍生物及其用途
CS244698B2 (cs) Způsob výroby v poloze 9 substituovaných derivátů 4-oxo-4H- -pyrido[1,2-a]-pyrimidinu

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed