CA2352066A1 - Process for the preparation of derivatized polymers - Google Patents
Process for the preparation of derivatized polymers Download PDFInfo
- Publication number
- CA2352066A1 CA2352066A1 CA002352066A CA2352066A CA2352066A1 CA 2352066 A1 CA2352066 A1 CA 2352066A1 CA 002352066 A CA002352066 A CA 002352066A CA 2352066 A CA2352066 A CA 2352066A CA 2352066 A1 CA2352066 A1 CA 2352066A1
- Authority
- CA
- Canada
- Prior art keywords
- group
- derivative
- polymer
- functional group
- activating reagent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups
Landscapes
- Chemical & Material Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyrrole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Indole Compounds (AREA)
Abstract
The invention relates to a method of producing a derivative of a polymer having at least one functional group. Said method is characterized in that i t comprises step (i): reacting the polymer having at least one functional grou p with at least one activating reagent or at least one derivative of an activating reagent in the homogeneous phase.
Claims (10)
1. Process for the preparation of a derivative of a polymer having at least one functional group, characterized in that the process comprises the following step (i):
(i) reaction of the polymer having at least one functional group, with at least one activating reagent or at least one derivative of an activating reagent in homogeneous phase.
(i) reaction of the polymer having at least one functional group, with at least one activating reagent or at least one derivative of an activating reagent in homogeneous phase.
2. Process according to Claim 1, characterized in that it comprises the further step (ii):
(ii) reaction of the reaction product from the polymer having at least one functional group and the activating reagent, with a derivatizing reagent.
(ii) reaction of the reaction product from the polymer having at least one functional group and the activating reagent, with a derivatizing reagent.
3. Process according to Claim 1, characterized in that the at least one derivative of the activating reagent is obtained by prior reaction of the activating reagent with a derivatizing reagent.
4. Process according to one of Claims 1 to 3, characterized in that the activating reagent is derived from a compound of the following structure (I) where R1 and R2 are identical or different and can be straight-chain, branched-chain or bridged to give a carbocycle or a heterocycle and are selected such that the activating reagent or the derivative of the activating reagent can be reacted in homogeneous phase with the polymer having at least one functional group.
5. Process according to one of Claims 1 to 4, characterized in that the functional group of the polymer having at least one functional group is an OH group, an NHR11 group, an SH group, an OSO3H group, an SO3H group, an OPO3H2 group, an OPO3HR11 group, a PO3H2 group, a PO3HR11 group, a COOH group or a mixture of two or more of these groups, where R11 is in each case selected such that the activating reagent or the derivative of the activating reagent can be reacted in homogeneous phase with the polymer having at least one functional group.
6. Derivative of a polymer having at least one functional group, preparable by a process which comprises the following step (i):
(i) reaction of the polymer having at least one functional group, with an activating reagent or a derivative of an activating reagent in homogeneous phase.
(i) reaction of the polymer having at least one functional group, with an activating reagent or a derivative of an activating reagent in homogeneous phase.
7. Derivative of a polymer having at least three functional groups, obtainable by a process as claimed in any of claims 1 to 5, where at least two of the functional groups are derivatized in such a way that they interact with a suitable substrate as receptor groups and at least one functional group having non-substrate-specific action and/or a monomer unit without a functional group lies between two of these derivatized groups.
8. Derivative of a polymer having at least one functional group, obtainable by a process as claimed in any of claims 1 to 5, which acts as a receptor for the binding of at least one substrate via non-covalent receptor-substrate interaction, characterized in that the binding of the at least one substrate can take place via at least two different types of interactions on account of the chemical constitution of the receptor groups.
9. Process for the bonding of at least one substrate to at least one receptor group via non-covalent receptor-substrate interaction, characterized in that the compound employed having at least one receptor group is a derivative of a polymer having at least one functional group, prepared by a process according to one of Claims 1 to 5, or a derivative according to one of Claims 6 to 8.
10. Compound of the general structure (X) characterized in that R0 is a halogen atom or a radical of the structure(X') and R1', R2', R1" and R2" are identical or different and are hydrogen, straight-chain or branched-chain alkyl, aryl, cycloalkyl, heterocyclic or aralkyl radicals having up to 30 C atoms, or either R1' and R2' or R1" and R2" or both R1' and R2' and R1" and R2" are linked to at least one carbocycle or to at least one heterocycle or to at least one carbocycle and to at least one heterocycle, compounds of the following structures (X1) to (X7) being excluded:
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19855173.8 | 1998-11-30 | ||
| DE19855173A DE19855173C2 (en) | 1998-11-30 | 1998-11-30 | Process for the preparation of derivatized polymers and derivatives of functional group-containing polymers and process for substrate binding |
| PCT/EP1999/009200 WO2000032649A1 (en) | 1998-11-30 | 1999-11-26 | Method of producing derivatized polymers |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2352066A1 true CA2352066A1 (en) | 2000-06-08 |
| CA2352066C CA2352066C (en) | 2010-07-13 |
Family
ID=7889484
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2352066A Expired - Fee Related CA2352066C (en) | 1998-11-30 | 1999-11-26 | Process for the preparation of derivatized polymers |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1149118B1 (en) |
| JP (2) | JP4737832B2 (en) |
| AT (1) | ATE349471T1 (en) |
| AU (1) | AU1655900A (en) |
| CA (1) | CA2352066C (en) |
| DE (2) | DE19860972A1 (en) |
| ES (1) | ES2280127T3 (en) |
| WO (1) | WO2000032649A1 (en) |
| ZA (1) | ZA200104298B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19957018A1 (en) * | 1999-11-26 | 2001-06-13 | Gottschall Instruction Ges Fue | Process for applying a polymer to a support |
| ES2545069T3 (en) * | 2003-03-25 | 2015-09-08 | Instraction Gmbh | Procedure for selective binding of a substrate to sorbents by at least bivalent binding |
| US7361767B2 (en) * | 2003-11-14 | 2008-04-22 | 3M Innovative Properties Company | N-sulfonyldicarboximide containing tethering compounds |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH606196A5 (en) * | 1975-06-18 | 1978-10-31 | Ciba Geigy Ag | Polymers crosslinkable by electromagnetic radiation |
| US4076916A (en) * | 1975-11-03 | 1978-02-28 | Massachusetts Institute Of Technology | Fluorinated functionalized polymers |
| SE431758B (en) * | 1977-03-04 | 1984-02-27 | Pharmacia Fine Chemicals Ab | AS THE USE OF THE TIOLATION REAGENT OR BERRY MATRIX FOR ENZYMERS DERIVATIVE OF A SH GROUPING POLYMER |
| CH652729A5 (en) * | 1982-04-28 | 1985-11-29 | Ciba Geigy Ag | LIGHT CROSSLINKABLE POLYMERS WITH SIDE-SIDED THIOAETHERIMIDYL GROUPS. |
| DE4322884A1 (en) * | 1992-10-09 | 1994-04-14 | Bayer Ag | Biologically active polymers |
| JPH0782489A (en) * | 1993-09-17 | 1995-03-28 | Dai Ichi Kogyo Seiyaku Co Ltd | Thermoplastic resin composition |
| DE4341524C2 (en) * | 1993-12-06 | 1997-01-16 | Gluesenkamp Karl Heinz Dr | Process for immobilizing biomolecules and affinity ligands on polymeric supports |
| US5582955A (en) * | 1994-06-23 | 1996-12-10 | State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of The University Of Oregon | Chemical functionalization of surfaces |
| TW318861B (en) * | 1994-08-16 | 1997-11-01 | Mitsui Toatsu Chemicals | |
| FR2724461B1 (en) * | 1994-09-09 | 1996-12-20 | Prolabo Sa | BIOTINYLATED LATEX MICROSPHERE, PROCESS FOR PREPARING SUCH MICROSPHERE, AND USE AS A BIOLOGICAL DETECTION AGENT |
-
1998
- 1998-11-30 DE DE19860972A patent/DE19860972A1/en not_active Ceased
-
1999
- 1999-11-26 ES ES99959351T patent/ES2280127T3/en not_active Expired - Lifetime
- 1999-11-26 AU AU16559/00A patent/AU1655900A/en not_active Abandoned
- 1999-11-26 EP EP99959351A patent/EP1149118B1/en not_active Expired - Lifetime
- 1999-11-26 JP JP2000585289A patent/JP4737832B2/en not_active Expired - Fee Related
- 1999-11-26 AT AT99959351T patent/ATE349471T1/en active
- 1999-11-26 WO PCT/EP1999/009200 patent/WO2000032649A1/en active IP Right Grant
- 1999-11-26 CA CA2352066A patent/CA2352066C/en not_active Expired - Fee Related
- 1999-11-26 DE DE59914107T patent/DE59914107D1/en not_active Expired - Lifetime
-
2001
- 2001-05-25 ZA ZA200104298A patent/ZA200104298B/en unknown
-
2009
- 2009-10-30 JP JP2009251039A patent/JP2010059433A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ES2280127T3 (en) | 2007-09-01 |
| AU1655900A (en) | 2000-06-19 |
| JP2010059433A (en) | 2010-03-18 |
| CA2352066C (en) | 2010-07-13 |
| EP1149118A1 (en) | 2001-10-31 |
| DE19860972A1 (en) | 2001-04-26 |
| JP2002531599A (en) | 2002-09-24 |
| WO2000032649A1 (en) | 2000-06-08 |
| JP4737832B2 (en) | 2011-08-03 |
| EP1149118B1 (en) | 2006-12-27 |
| ZA200104298B (en) | 2002-05-23 |
| ATE349471T1 (en) | 2007-01-15 |
| DE59914107D1 (en) | 2007-02-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20181126 |