CA2351059A1 - Acylated benzylmaltosides as inhibitors of smooth muscle cell proliferation - Google Patents

Acylated benzylmaltosides as inhibitors of smooth muscle cell proliferation Download PDF

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Publication number
CA2351059A1
CA2351059A1 CA002351059A CA2351059A CA2351059A1 CA 2351059 A1 CA2351059 A1 CA 2351059A1 CA 002351059 A CA002351059 A CA 002351059A CA 2351059 A CA2351059 A CA 2351059A CA 2351059 A1 CA2351059 A1 CA 2351059A1
Authority
CA
Canada
Prior art keywords
carbon atoms
substituted
pharmaceutically acceptable
acceptable salt
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002351059A
Other languages
English (en)
French (fr)
Inventor
Scott Christian Mayer
Paul Jeffrey Dollings
Robert Emmett Mcdevitt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2351059A1 publication Critical patent/CA2351059A1/en
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18—Acyclic radicals, substituted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA002351059A 1998-11-24 1999-11-23 Acylated benzylmaltosides as inhibitors of smooth muscle cell proliferation Abandoned CA2351059A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US19880498A 1998-11-24 1998-11-24
US09/198,804 1998-11-24
PCT/US1999/027777 WO2000034295A2 (en) 1998-11-24 1999-11-23 Acylated benzylmaltosides as inhibitors of smooth muscle cell proliferation

Publications (1)

Publication Number Publication Date
CA2351059A1 true CA2351059A1 (en) 2000-06-15

Family

ID=22734932

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002351059A Abandoned CA2351059A1 (en) 1998-11-24 1999-11-23 Acylated benzylmaltosides as inhibitors of smooth muscle cell proliferation

Country Status (7)

Country Link
EP (1) EP1133510A2 (zh)
JP (1) JP2003521460A (zh)
CN (1) CN1329616A (zh)
AU (1) AU3791200A (zh)
BR (1) BR9915632A (zh)
CA (1) CA2351059A1 (zh)
WO (1) WO2000034295A2 (zh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0814440A2 (pt) * 2007-07-19 2014-08-19 Integrated Plant Genetics Inc Uso de proteínas de ruptura de membrana exterior de bacteriófago expressas em plantas para o controle de bactérias gram-negativas
CN118406096B (zh) * 2024-06-28 2024-08-23 成都施贝康生物医药科技有限公司 一种麦芽糖类脂肪酸酯类化合物及其制备方法和应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5565432A (en) * 1994-11-07 1996-10-15 American Home Products Corporation Smooth muscle cell proliferation inhibitors
IL115745A (en) * 1994-11-07 2000-11-21 American Home Prod Acylated benzylglycosides and pharmaceutical compositions containing them
US5498775A (en) * 1994-11-07 1996-03-12 American Home Products Corporation Polyanionic benzylglycosides as inhibitors of smooth muscle cell proliferation
CA2350066A1 (en) * 1998-11-24 2000-06-02 American Home Products Corporation Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation
AU1743800A (en) * 1998-11-24 2000-06-26 American Home Products Corporation Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation
CA2350753A1 (en) * 1998-11-24 2000-06-02 American Home Products Corporation Benzylmaltosides as inhibitors of smooth muscle cell proliferation

Also Published As

Publication number Publication date
BR9915632A (pt) 2001-08-07
EP1133510A2 (en) 2001-09-19
JP2003521460A (ja) 2003-07-15
AU3791200A (en) 2000-06-26
WO2000034295A3 (en) 2000-11-23
CN1329616A (zh) 2002-01-02
WO2000034295A2 (en) 2000-06-15

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